J-GLOBAL ID:200904099613543410  Research Project code:9800015832 Update date:Dec. 13, 2002

Expression and isolation of dihydrofolate reductase of P. falciparum in E. coli for developing novel anti-malarials by computer drug design

Study period:1992 - 1997
Organization (1):
Investigating Researcher (3):
Research overview:
Malaria is one of the major lethal infectious diseases on the people of this world. The objective of the proposed research is to set a new strategy for the development of a practical way for the drug design utilizing the genetic engeneering technology to express malarial enzyme in bacterial cell.
Keywords (8):
antimalarial ,  Plasmodium ,  dihydrofolate ,  drug ,  gene ,  vector(DNA) ,  Escherichia ,  screening(inspection)
Research program: Ordinary Research
Research budget: 1996: \6,000,000

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