Proj
J-GLOBAL ID:200904099613543410  Research Project code:9800015832 Update date:Dec. 13, 2002

Expression and isolation of dihydrofolate reductase of P. falciparum in E. coli for developing novel anti-malarials by computer drug design

マラリア病原虫のジヒドロ葉酸還元酵素の単離精製とドラッグデザインによる抗マラリア剤の開発
Study period:1992 - 1997
Organization (1):
Investigating Researcher (3):
Research overview:
Malaria is one of the major lethal infectious diseases on the people of this world. The objective of the proposed research is to set a new strategy for the development of a practical way for the drug design utilizing the genetic engeneering technology to express malarial enzyme in bacterial cell.
Keywords (8):
antimalarial ,  Plasmodium ,  dihydrofolate ,  drug ,  gene ,  vector(DNA) ,  Escherichia ,  screening(inspection)
Research program: Ordinary Research
Research budget: 1996: \6,000,000

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