Chem
J-GLOBAL ID:200907083991620926   Nikkaji number:J2.645.513H

SB-497115

SB-497115
Substance type:
Substance type
Substance type classified into 3 categories.
Decided structure: Substances with a clear structure
Undicided Structure: Substances with unknown or undetermined structure
Mixtures: Mixtures, racemic compounds, or compounds with relative structural arrangements
Decided structure
Molecular formula: C25H22N4O4
Molecular formula furigana: C25-H22-N4-O4
Molecular weight: 442.475
InChI: InChI=1S/C25H22N4O4/c1-14-10-11-19(12-15(14)2)29-24(31)22(16(3)28-29)27-26-21-9-5-8-20(23(21)30)17-6-4-7-18(13-17)25(32)33/h4-13,26,30H,1-3H3,(H,32,33)/b27-22-
InChI key: XDXWLKQMMKQXPV-QYQHSDTDSA-N
SMILES: CC1=NN(C(=O)/C/1=N\Nc1cccc(c2cccc(c2)C(=O)O)c1O)c1ccc(C)c(C)c1
Systematic name  (4):
  • 3′-[(Z)-2-[1-(3,4-ジメチルフェニル)-1,5-ジヒドロ-3-メチル-5-オキソ-4H-ピラゾール-4-イリデン]ヒドラジノ]-2′-ヒドロキシビフェニル-3-カルボン酸
  • 3′-[(2Z)-2-[1-(3,4-ジメチルフェニル)-3-メチル-5-オキソ-1H-ピラゾール-4(5H)-イリデン]ヒドラジノ]-2′-ヒドロキシビフェニル-3-カルボン酸
  • 3'-{2-[(4Z)-1-(3,4-ジメチルフェニル)-3-メチル-5-オキソ-4,5-ジヒドロ-1H-ピラゾール-4-イリデン]ヒドラジン-1-イル}-2'-ヒドロキシ-[1,1'-ビフェニル]-3-カルボン酸
  • 3'-{2-[(4Z)-1-(3,4-dimethylphenyl)-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-ylidene]hydrazin-1-yl}-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid
Other name (6):
  • 3′-[(Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazole-4-ylidene]hydrazino]-2′-hydroxybiphenyl-3-carboxylic acid
  • エルトロンボパグ
  • Eltrombopag
  • SB-497115
  • 3′-[(2Z)-2-[1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazole-4(5H)-ylidene]hydrazino]-2′-hydroxybiphenyl-3-carboxylic acid
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CAS registry number: 496775-61-2
Application (3):
hematinic ,  thrombocyte ,  Thrombocytopenia
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