MURATA Toshihiro

ムラタトシヒロ | MURATA Toshihiro

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://scholar.google.co.jp/citations?user=y6YCE2YAAAAJ&hl=ja

Research field (3)： Clinical pharmacy , Pharmaceuticals - chemistry and drug development , Bioorganic chemistry

Research keywords (15)： Biological Interactions , Plant , Insect , Domestic Animal , Disease Vector , Zoonosis , Infection Control Measures , International Collaboration , Traditional Medicine , Mongolia , Japanese Parsley <i>Oenanthe javanica</i> , Industry-Academia-Government Collaboration , Pharmacognosy , Natural Product Chemistry , Chemical Ecology

Research theme for competitive and other funds (14)：

2021 - 2026 Chemical investigation of traditional medicines for controlling infectious diseases, including zoonosis, oriented to eliminate pathogens and vectors
2024 - 2025 抗トリパノソーマ活性物質の動物生体内動態解析・安全性評価に向けた分析方法の検討
2023 - 2024 Structure-activity relationship of flavonoids from crude drug (ex. Scutellaria Radix and Astragalus Radix) for Kampo preparations against protozoan pathogens.
2019 - 2022 Investigation of compounds for controlling infectious diseases from nomadic traditional useful plants guided by insect assay systems oriented to vectors
2019 - 2020 モンゴル国薬用植物由来抗トリパノソーマ活性化合物をシーズとした派生化合物の合成・探索と構造活性相関及び細胞毒性の検討

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Papers (62)：

Nanami Kurosawa, Yohei Takeda, Yoshimi Ichimaru, Dulamjav Jamsransuren, Sachiko Matsuda, Yoshinobu Ishikawa, Minori Yamaguchi, Haruko Ogawa, Kenroh Sasaki, Toshihiro Murata. Chemical constituents of five Saxifraga species and their virucidal activities. Fitoterapia. 2024. 106215-106215
Nanang R Ariefta, Koichi Narita, Toshihiro Murata, Yoshifumi Nishikawa. Evaluation of the antiplasmodial efficacy of synthetic 2,5-diphenyloxazole analogs of compounds naturally derived from Oxytropis lanata. International journal for parasitology. Drugs and drug resistance. 2024. 25. 100540-100540
Punsantsogvoo Otgonsugar, Buyanmandakh Buyankhishig, Tserendorj Undrakhbayar, Byambajav Bilguun, Kenroh Sasaki, Bekh-Ochir Davaapurev, Javzan Batkhuu, Tseesuren Byambajav, Toshihiro Murata. Phytochemical investigation of aerial parts of Woodsia ilvensis and its plasmin-inhibitory activity in vitro. Phytochemistry. 2023
Toshihiro Murata, Dulamjav Jamsransuren, Sachiko Matsuda, Haruko Ogawa, Yohei Takeda. Rapid Virucidal Activity of Japanese Saxifraga Species-Derived Condensed Tannins against SARS-CoV-2, Influenza A Virus, and Human Norovirus Surrogate Viruses. Applied and environmental microbiology. 2023. 89. 6. e0023723
Stipan Nurbyek, Buyanmandakh Buyankhishig, Keisuke Suganuma, Yoshinobu Ishikawa, Mika Kutsuma, Marie Abe, Kenroh Sasaki, Bekh-Ochir Davaapurev, Javzan Batkhuu, Toshihiro Murata. Phytochemical investigation of Scutellaria scordiifolia and its trypanocidal activity. Phytochemistry. 2023. 209. 113615-113615

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Patents (3)：

植物由来抽出物を有効成分とするウイルス不活化剤
トリパノソーマ症の治療薬及び予防薬
新規E/Z体混合ノルリグナンを含む抗アレルギー剤及びコリンエステラーゼ阻害剤

Lectures and oral presentations (6)：

薬草セミナー身近な野菜(せり)や野草の成分とその機能性
(薬草セミナー(主催: 宮城県保健福祉部薬務課, 日本薬用植物友の会) 2023)
(山形版) 薬草の成分から開発されたくすり
(令和5年度日本薬用植物友の会山形支部公開講演会 2022)
モンゴル国遊牧民の伝承に学ぶ薬草の活用法
(薬草セミナー(主催: 宮城県保健福祉部薬務課, 日本薬用植物友の会) 2020)
モンゴル国薬用植物の成分薬効解析(学術奨励賞受賞講演)
(日本生薬学会第66回年会 2019)
昆虫試験系を活用した植物成分混合系による薬用効果や協奏作用の解明(日本薬学会生薬天然物部会奨励研究受賞講演)
(第20回天然薬物の開発と応用シンポジウム 2016)

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Education (2)：

- 2007 Kyoto University
- 2005 University of Shizuoka School of Pharmaceutical Sciences

Professional career (1)：

Ph.D (University of Shizuoka)

Work history (2)：

2016/04 - 現在 Tohoku Medical and Pharmaceutical University
2007 - - 東北薬科大学

Awards (2)：

2019/09 - The Japanese Society of Pharmacognosy Academic Encouragement Award Chemical and Pharmacological invastigations from Mongolian Medicinal Plants
2014/11 - The Pharmaceutical Society of Japan, Division of Natural Medicines Research Award for Young Scientists by Division of Natural Medicines Biological assays using insects give clues to the solution of combined effects of crude drugs

Association Membership(s) (4)：

JAPANESE SOCIETY OF APPLIED ENTOMOLOGY AND ZOOLOGY , JAPAN SOCIETY FOR BIOSICENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY , THE JAPANESE SOCIETY OF PHARMACOGNOSY , THE PHARMACEUTICAL SOCIETY OF JAPAN

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