ISHIHARA TSUTOMU

イシハラツトム | ISHIHARA TSUTOMU

Affiliation and department：
Job title： Professor

Research field (1)： Nanobioscience

Research keywords (4)：バイオ医薬 , nanoparticle , nanomedicine , DDS

Research theme for competitive and other funds (5)：

2020 - 2023 Treatment of chronic arterial occlusion with biodegradable nanoparticles encapsulating anti-miRNA oligonucleotides
2017 - 2020 Development of lecithin-modified therapeutic proteins as biobetters
2014 - 2017 Development of multifunctional polyplexes without polycations
2010 - 2012 Establishment of novel therapy for hepatitis C by double DDS drugs
1998 - 1999 細胞認識機能を有した新規生分解性ナノ微粒子型遺伝子キャリアーの開発

Papers (59)：

Tsutomu Ishihara, Ken-ichiro Tanaka, Ayaka Takafuji, Keita Miura, Tohru Mizushima. Attenuation of LPS-Induced Lung Injury by Benziodarone via Reactive Oxygen Species Reduction. International Journal of Molecular Sciences. 2023. 24. 12. 10035-10035
Shibata R, Ishihara T, Tsukamoto T, Oishi Y, Fujimori A, Shibasaki Y. Synthesis of tetraazacalixarene triazine-containing poly (dimethylsiloxane) with elastic property induced by pinning effect of the calixarene ring. European Polymer J. 2022. 162. 110890
Kaneko K, Ishihara T. Development of liver-specific ribavirin-loaded nanoparticles with reduced cytotoxicity. Cogent Medicine. 2017. 4. 1. 1418133
Yoshihiko Kihara, Riho Maeda, Azusa Imaizumi, Tsukasa Ichikawa, Nobukatsu Nemoto, Tsutomu Ishihara, Nobutaka Hirano, Mitsuru Haruki. Alkyne-Functionalized Cationic Polysiloxane Polymers Conjugated with Targeting Molecules by Click Reactions for DNA Delivery. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY. 2017. 17. 7. 5081-5089
Tsutomu Ishihara, Misaki Shibui, Takaya Hoshi, Tohru Mizushima. Scavenging of superoxide anions by lecithinized superoxide dismutase in HL-60 cells. MOLECULAR BIOSYSTEMS. 2016. 12. 1. 274-282

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MISC (11)：

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Patents (5)：

Books (3)：

Lectures and oral presentations (38)：

化学修飾によるタンパク質の細胞内デリバリー
(2023年度高分子学会東北支部研究発表会 2023)
骨を標的としたビスホスホネート封入高分子ナノ粒子の開発
(2023年度高分子学会東北支部研究発表会 2023)
Intracellular delivery of proteins by chemical modification
(International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan 2023)
Development of a bone-specific drug delivery system using polymeric nanoparticles modified with peptides on their surfaces
(International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan 2023)
ホスファチジルコリン修飾タンパク質の細胞内デリバリー
(2022年度化学系学協会東北大会 2022)

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Awards (2)：

Association Membership(s) (3)：

Controlled Release Society , The Japan Society of Drug Delivery System , The society of polymer science

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