Susaki Etsuo A

スサキエツオ | Susaki Etsuo A

Affiliation and department：
Job title： Professor
Other affiliations (4)：

Juntendo University Nakatani Biomedical Spatialomics Hub, Graduate School of Medicine Head
National Institutes for Quantum and Radiological Science and Technology Institute for Quantum Life Science Visiting Scientist
RIKEN Center for Biosystems Dynamics Research Visiting Scientist
CUBICStars Co. Executive officer

Homepage URL (1)： http://www.dbsb.science

Research field (6)： Genetics , Cell biology , Molecular biology , Neuroanatomy and physiology , Neuroscience - general , Medical biochemistry

Research keywords (10)： Hydra biology & biotechnology , Aging , Cell Cycle , Three-dimensional histology , Systems biology , Bioimaging , Tissue clearing , 発生生物学 , 合成生物学 , Mouse genetics

Research theme for competitive and other funds (24)：

2023 - 2030 Interdisciplinary research on autophagy: From working principles to pathophysiology
2022 - 2028 Advanced Bioimaging Support
2022 - 2026 早期血管老化部位の網羅的全身探索と医学的介入効果の検証
2020 - 2024 title in Japanese
2022 - 2023 title in Japanese

2018 - 2023 Designing the mammalian biological oscillators

2019 - 2022 Development of whole-organ 3D staining method for the analysis of protein expression, modification, and activity

2017 - 2022 (Investigation of cellular diversity by a comprehensive 3D imaging method)

2018 - 2020 (Detecting Global States and Dynamics in Neural Circuit)

2018 - 2020 Development of basic technology for spatial genomics of in three-dimensional tissues

2020 - title in Japanese

2012 - 2019 (Development of tissue-clearing technology for high-throughput whole-body imaging)

2015 - 2019 (title in Japanese)

2015 - 2019 (Development of next-generation mouse genetics toward comprehensive identification of phenotype-related cells)

2016 - 2018 (Detecting Global Dynamics in Neural Circuit)

2014 - 2018 (Development of a 3D imaging method for temporal and spacial gene expression profiling and circuit analysis)

2017 - 2018 Identifying the brain's circuit for selective attentional centers

2014 - 2017 Developing basic technologies toward comprehensive circuit mapping of the primate brain

2013 - 2017 哺乳類概日振動体の構成的な理解

2014 - 2015 (Identification of brain state transitions by monitoring whole brain activities throughout 24 hours)

2011 - 2013 High-throughput Preparation of Gene-targeted Mice by Controlling the Ratio of Cell Types in Developmental Embryos

2010 - 2011 (Identification and analysis of sleep/wake-regulating neural circuits)

2009 - 2011 (Functional analysis of CDK inhibitors during development)

2009 - 2010 (Analysis of in vivo role of CDK inhibitors regulating developmental process and stem cell function)

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Papers (47)：

Etsuo A Susaki. Unlocking the potential of large-scale 3D imaging with tissue clearing techniques. Microscopy. 2024
Rin Yanai, Tomoki T Mitani, Etsuo A Susaki, Takeharu Minamihisamatsu, Masafumi Shimojo, Yuri Saito, Hiroshi Mizuma, Nobuhiro Nitta, Daita Kaneda, Yoshio Hashizume, et al. A novel tauopathy model mimicking molecular and spatial aspects of human tau pathology. Brain Communications. 2024. 6. 5. fcae326
Tomoki T Mitani, Etsuo A Susaki, Katsuhiko Matsumoto, Hiroki R Ueda. Realization of cellomics to dive into the whole-body or whole-organ cell cloud. Nature methods. 2024. 21. 1138-1142
Kohei Otomo, Takaki Omura, Yuki Nozawa, Steven J Edwards, Yukihiko Sato, Yuri Saito, Shigehiro Yagishita, Hitoshi Uchida, Yuki Watakabe, Kiyotada Naitou, et al. descSPIM: an affordable and easy-to-build light-sheet microscope optimized for tissue clearing techniques. Nature communications. 2024. 15. 1. 4941-4941
Md Nasful Huda Prince, Benjamin Garcia, Cory Henn, Yating Yi, Etsuo A. Susaki, Yuki Watakabe, Tomomi Nemoto, Keith A. Lidke, Hu Zhao, Irene Salinas Remiro, et al. Signal improved ultra-fast light-sheet microscope for large tissue imaging. Communications Engineering. 2024. 3. 1. 59

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MISC (70)：

来栖玲央, 洲崎悦生. Tissue/organ-wide spatial single-cell analysis with advanced microscopy techniques. 生体の科学. 2024. 75. 4. 305-309
Atsushi Takahashi-Kanemitsu, Etsuo A. Susaki. A comprehensive whole cell analysis of organoids by Cell-omics technology. Jikken-Igaku (book title in Japanese). 2024. 42. 5. 176 (810)-182 (816)
Akira L. Yoshikawa, Kohei Otomo, Etsuo A. Susaki. Overview of light-sheet fluorescence microscopy and tissue clearing. OPTRONICS. 2024. 507. 3. 65-69
Etsuo A. Susaki. Development and perspective of cell-omics technology. 生化学. 2022. 94. 1. 26-36
Etsuo A. Susaki. Basics and Applications of Tissue Clearing Technology. TCI mail. 2022. 189. 189. 10-17

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Patents (6)：

BIOLOGICAL TISSUE;STAINING REAGENT;BIOLOGICAL TISSUE;STAINING KIT AND;BIOLOGICAL TISSUE;STAINING METHOD
CUBIC-HV(TM)
Composition for preparing biomaterial with excellent light-transmitting property, and use thereof
光透過性に優れた生物材料を調製するための組成物およびその利用(国内出願)
(A screening method for anti-obesity drugs)

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Books (8)：

Light-sheet imaging guide
Yodosha 2023 ISBN:9784758122689
Handbook of Tissue Optical Clearing - New Prospects in Optical Imaging. Editors: Dan Zhu, Elina A. Genina, Valery V. Tuchin
CRC Press 2022 ISBN:9781000466300
Handbook for Medical Engineering
NTS inc. 2022 ISBN:9784860437350
Cutting-edge Analytical Techniques, 2nd Edition
NTS inc. 2022 ISBN:9784860437374
Bio-innovation - Novel Developments by New Biotechnologies (Japanese)
CMC Publishing 2019 ISBN:9784781314112

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Lectures and oral presentations (166)：

Tissue Clearing Technologies and Their Applications in Cancer Research and Drug Discovery
(9th International Conference on Cancer Research & Drug Development 2024)
(title in Japanese)
(The 63rd Annual Autumn Meeting of The Japanese Society of Clinical Cytology 2024)
(title in Japanese)
(Seminar at Juntendo University Hospital 2024)
Cell-omics technology: dive into the three-dimensional whole cell cloud
(The 97th Annual Meeting of the Japanese Biochemical Society 2024)
(title in Japanese)
(Symposium at Yamaguchi University 2024)

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Professional career (1)：

M.D., Ph.D (Kyushu University)

Work history (14)：

2021/04 - 現在 Department of Biochemistry and Systems Biomedicine, Juntendo University Graduate School of Medicine Professor
2024/04 - 2029/03 Juntendo University Nakatani Biomedical Spatialomics Hub, Graduate School of Medicine Head
2019/11 - 2021/03 Graudate School of Medicine, The University of Tokyo Department of Systems Pharmacology Associate professor
2019/09 - 2020/03 Waseda University Faculty of Science and Engineering
2017/01 - 2019/10 UTokyo Graduate School of Medicine Department of Systems Pharmacology Lecturer/Senior research associate

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Awards (7)：

2021/09 - U.S. National Academy of Medicine International Catalyst Award of Healthy Longevity Global Competition 2021 "Clarifying the origins and very early processes of aging in tissue"
2019/03 - JST さきがけ「1細胞解析」研究領域特別賞
2017/04 - The Minister of Education, Culture, Sports, Science and Technology The Young Scientists’ Prize of The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology "Development of novel technologies toward the organism-level systems biology"
2017/03 - 国立研究開発法人日本医療研究開発機構/ニューヨーク科学アカデミー Interstellar Initiative 選抜参加
2015/03 - The 88th Annual Meeting of the Japanese Pharmacological Society Selected Presentation Award

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Association Membership(s) (4)：

The Japanese Association for Molecular Target Therapy of Cancer , The Japanese Biochemical Society , Japanese Society of Digital Pathology , 日本分子生物学会

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