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J-GLOBAL ID:201001013734737597   Update date: Feb. 01, 2024

yao ikuko

ヤオ イクコ | yao ikuko
Affiliation and department:
Research field  (4): Cell biology ,  Molecular biology ,  Neuroscience - general ,  Medical biochemistry
Research keywords  (12): mass spectrometry ,  imaging ,  蛋白質分解 ,  神経可塑性 ,  SCRAPPER ,  神経科学 ,  プロテオーム ,  シナプス ,  老化 ,  蛋白質 ,  包括脳ネットワーク ,  統合脳・分子脳科学
Research theme for competitive and other funds  (16):
  • 2022 - 2024 Development of a new topological data analysis by integration with computational vison theory
  • 2021 - 2024 慢性疼痛が惹起する精神疾患を司る皮質下ー皮質の局所神経回路
  • 2021 - 2024 プロテオームとミネラロームのイメージングを用いたMMP-2による再生骨成熟の解析
  • 2020 - 2023 Regulation of distribution of motor proteins in synapse by ubiquitin ligase
  • 2018 - 2021 Search for matrix proteins that regulate calcification by analyzing degradome for calcified tissues of MMP 2 - deficient mice
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Papers (71):
  • Daisuke Kato, Yuki Aoyama, Kazuki Nishida, Yutaka Takahashi, Takumi Sakamoto, Ikuko Takeda, Tsuyako Tatematsu, Shiori Go, Yutaro Saito, Shiho Kunishima, et al. Regulation of lipid synthesis in myelin modulates neural activity and is required for motor learning. Glia. 2023
  • Yashuang Ping, Kenji Ohata, Kenji Kikushima, Takumi Sakamoto, Ariful Islam, Lili Xu, Hengsen Zhang, Bin Chen, Jing Yan, Fumihiro Eto, et al. Tubulin Polyglutamylation by TTLL1 and TTLL7 Regulate Glutamate Concentration in the Mice Brain. Biomolecules. 2023. 13. 5. 784-784
  • Hidemoto Yamada, Lili Xu, Fumihiro Eto, Rei Takeichi, Ariful Islam, Md Ai Mamun, Chi Zhang, Ikuko Yao, Takumi Sakamoto, Shuhei Aramaki, et al. Changes of Mass Spectra Patterns on a Brain Tissue Section Revealed by Deep Learning with Imaging Mass Spectrometry Data. Journal of the American Society for Mass Spectrometry. 2022. 33. 9. 1607-1614
  • Yasuko Fujisawa, Hiroyuki Ono, Alu Konno, Ikuko Yao, Hiroaki Itoh, Takashi Baba, Kenichirou Morohashi, Yuko Katoh-Fukui, Mami Miyado, Maki Fukami, et al. Intrauterine Hyponutrition Reduces Fetal Testosterone Production and Postnatal Sperm Count in the Mouse. Journal of the Endocrine Society. 2022. 6. 4. bvac022
  • Tomohiko Matsuo, Tomoko Isosaka, Yuichiro Hayashi, Lijun Tang, Akihiro Doi, Aiko Yasuda, Mikio Hayashi, Chia-Ying Lee, Liqin Cao, Natsumaro Kutsuna, et al. Thiazoline-related innate fear stimuli orchestrate hypothermia and anti-hypoxia via sensory TRPA1 activation. Nature Communications. 2021. 12. 1
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MISC (40):
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Books (6):
  • Lipid machinery investigation using MALDI imaging mass spectrometry
    "Bioactive Lipid Mediators: Current Reviews and Protocols" from Springer Japan 2015
  • 質量分析イメージングによる脳内環境の可視化
    遺伝子医学MOOK 26号 2014
  • Imaging Mass Spectrometry (IMS) for Biological Application
    Mass Spectrometry Handbook 2012
  • Role of synapse-localized E3 ubiquitin ligase in regulating neural transmissionpathology「The ubiquitin proteasome system in nervous system: from physiology to pathology」
    NOVA Publishers 2009
  • 「Practical methods and applications of Imaging Mass Spectrometry” Mitsutoshi Setou」
    Springer Japan 2009
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Lectures and oral presentations  (6):
  • Super resolution imaging of synaptic site to analyze the transmission regulation
    (2017)
  • Mass spectrometry imaging for transitional condition of Rivastigmine to the mouse brain
    (2016)
  • 質量顕微鏡法による神経疾患モデル動物解析に向けて
    (第121回日本解剖学会総会・全国学術集会 2016)
  • ユビキチンリガーゼ SCRAPPERによるシナプス可塑性の調節
    (第93回日本生理学会大会 2016)
  • 質量分析イメージングの実際
    (第56回日本組織細胞化学会総会 2015)
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Education (1):
  • Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences
Professional career (1):
  • Ph. D (Tokyo Medical and Dental University)
Work history (3):
  • 2019/04 - 現在 Kwansei Gakuin University Department of Biomedical Chemistry, School of Science and Technology Professor
  • 2013 - 2019 Hamamatsu University School of Medicine Dept of Optical Imaging, Medical Photonics Research Center Associate Professor, PI
  • 2013 - 2013 Kansai Medical University Dept of Med Chem Associate Professor
Awards (6):
  • 2013/09 - 日本医用マススペクトル学会 2013年度日本医用マススペクトル学会奨励賞
  • 2012 - 2012年度武田科学振興財団研究助成 医学系研究奨励
  • 2011 - 第36回医用マススペクトル学会年会優秀ポスター賞
  • 2010 - 関西医科大学 和田喜代子賞
  • 2009 - 第34回医用マススペクトル学会年会優秀ポスター賞
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Association Membership(s) (9):
北米神経科学会 ,  アメリカ細胞生物学会 ,  日本細胞生物学会 ,  日本分子生物学会 ,  日本生化学会 ,  日本神経科学学会 ,  The Mass Spectrometry Society of Japan ,  America Society for Mass Spectrometry ,  Japanese Society for Medical Mass Spectrometry
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