Kobayashi Masato

• 2022 - 2026 細胞内レドックス制御を司るがん幹細胞治療の標的トランスポーター画像診断薬の開発
• 2022 - 2026 原発性アルドステロン症における新治療戦略ー安全かつ高奏功な根本治療の開発
• 2022 - 2025 Development of Mitochondria-Targeted Theranostic Agents for Cancer-Specific Glutaminolysis
• 2021 - 2025 ナトリウム共役能動輸送型糖輸送体を標的としたセラノスティクス薬剤の開発
• 2018 - 2021 Elucidation of renal tubular secretion mechanism of drugs and development of new renal functional methods in nuclear medicine
2017 - 2019 Development of therapeutic effect prediction method and cancer therapy enhancement method for internal radiation therapy (Fostering Joint International Research)
2015 - 2018 Development of high accuracy multidrug resistance prediction method using SPECT imaging for individualized anticancer therapy
2015 - 2017 Development strategy of tumor diagnostic agent by system upregulated functional biomolecule based on expression analysis of tumor associated transporter
2014 - 2017 Development of new radiopharmaceuticals targeting amino acid transporter system ASC, and system N
2013 - 2017 Development of a molecular targeted radiolabeled diagnostic agent useful for personalized drug therapy of psychoneurotic diseases
2012 - 2015 Quantitative measurement of a new small animal SPECT/CT scanner with a semiconductor detector
2010 - 2011 Acceleration of Cerebral Blood Flow and Oxygen Metabolism Measurement with Injectable 15O labeled Radiotracers and Effectiveness of Drug Treatment
2008 - 2011 Development of novel radiopharmaceuticals for diagnosis of cerebral neurodegeneration and functional recovery after intrastriatal grafts/gene therapy
- 2006 急性期虚血性脳疾患におけるPET診断簡略化を目指した自動検出解析システムの開発
- 2006 Development of auto detect and analysis system for PET imageing on acute cerebralvascular diseases

• Yuka Muranaka, Miki Matsue, Asuka Mizutani, Masato Kobayashi, Kakeru Sato, Ami Kondo, Yuri Nishiyama, Shusei Ohata, Kodai Nishi, Kana Yamazaki, et al. Evaluation of L-Alanine Metabolism in Bacteria and Whole-Body Distribution with Bacterial Infection Model Mice. International Journal of Molecular Sciences. 2023. 24. 5. 4775-4775
• Kakeru Sato, Asuka Mizutani, Yuka Muranaka, Jianwei Yao, Masato Kobayashi, Kana Yamazaki, Ryuichi Nishii, Kodai Nishi, Takeo Nakanishi, Ikumi Tamai, et al. Biological Distribution after Oral Administration of Radioiodine-Labeled Acetaminophen to Estimate Gastrointestinal Absorption Function via OATPs, OATs, and/or MRPs. Pharmaceutics. 2023. 15. 2
• Kakeru Sato, Tatsuya Seki, Asuka Mizutani, Yuka Muranaka, Shiho Hirota, Kodai Nishi, Kana Yamazaki, Ryuichi Nishii, Takeo Nakanishi, Ikumi Tamai, et al. A Single High-Dose Irradiation Changes Accumulation of Methotrexate and Gene Expression Levels of SLC and ABC Transporters in Cancer Cells. Frontiers in Pharmacology. 2023. 13. 1069321-1069321
• Asuka Mizutani, Masato Kobayashi, Riku Aibe, Yuka Muranaka, Kodai Nishi, Masanori Kitamura, Chie Suzuki, Ryuichi Nishii, Naoto Shikano, Yasuhiro Magata, et al. Measurement of Hepatic CYP3A4 and 2D6 Activity Using Radioiodine-Labeled O-Desmethylvenlafaxine. International journal of molecular sciences. 2022. 23. 19
• Asuka Mizutani, Masato Kobayashi, Makoto Ohuchi, Keita Sasaki, Yuka Muranaka, Yusuke Torikai, Shota Fukakusa, Chie Suzuki, Ryuichi Nishii, Shunji Haruta, et al. Indirect SPECT Imaging Evaluation for Possible Nose-to-Brain Drug Delivery Using a Compound with Poor Blood-Brain Barrier Permeability in Mice. Pharmaceutics. 2022. 14. 5

ｍore...

• 目代 佑太朗, 西 弘大, 小林 正和, 辻野 耕平, 川井 恵一, 工藤 崇. 99mTc-tetrofosminの肝集積メカニズムと肝集積阻害効果の検証. JSMI Report. 2017. 10. 2. 154-154
• 稲川 耕平, 丹羽 隆博, 西 弘大, 小林 正和, 川井 恵一. 脳腫瘍細胞におけるD-methionineの集積性と集積機序の検討. 核医学. 2016. 53. Suppl. S265-S265
• 小林 正和, 水谷 明日香, 辻内 孝文, 西 弘大, 福地 一樹, 川井 恵一. 99mTc放射性医薬品における腫瘍細胞外排泄機序の違い. JSMI Report. 2016. 9. 2. 203-203
• 高橋浩太郎, 水谷明日香, 佐藤達哉, 外間つづみ, 西弘大, 小林正和, 川井恵一. ¹²³I-IMP代謝物分析による臨床薬剤負荷時のCYP活性定量法. 核医学. 2015. 52. 3. 290
• Masato Kobayashi, Tetsuya Mori, Tetsuya Tsujikawa, Kazuhiro Ogai, Jyunko Sugama, Yasushi Kiyono, Keiichi Kawai, Hidehiko Okazawa. Comparison of image quality with ⁶²Cu and ⁶⁴Cu-labeled radiotracers in positron emission tomography whole-body phantom imaging. Hellenic Journal of Nuclear Medicine. 2015. 18. 2. 103-107

ｍore...

• - 2006 Kanazawa University

• Doctor of health sciences (Kanazawa University)
• Master of health sciences (Kanazawa University)

• 2019/04 - 現在 金沢大学医薬保健研究域保健学系
• 2009/03 - 2019/03 -: 金沢大学 助教
• 2007 - 2009 : 福井大学 助教
• 2006 - 2007 : 福井大学 COE研究員
• 2004 - 2005 : 先端医療振興財団 特別技術員

日本医学放射線学会 ,  日本医学物理学会 ,  日本分子イメージング学会 ,  日本核医学技術学会 ,  日本核医学会 ,  日本放射線技術学会 ,  Japan radiological society ,  Japan society of medical physics ,  Japanese society for molecular imaging ,  The Japanese Society of Nuclear Medicine Technology ,  The Japanese society of nuclear medicine ,  Japanese society of radiological technology