Rchr
J-GLOBAL ID:201001023189960831
Update date: Apr. 25, 2024
KAZUHIKO OCHIAI
オチアイ カズヒコ | KAZUHIKO OCHIAI
Affiliation and department:
Job title:
Associate Professor
Homepage URL (1):
http://www.nvlu.ac.jp/
Research field (2):
Veterinary medicine
, Animal production science
Research keywords (3):
分子生物学
, 基礎獣医学
, 実験動物学
Research theme for competitive and other funds (13):
- 2019 - 2024 細胞骨格ダイナミクスに基づく分子輸送制御システムの解明と革新的癌創薬への新展開
- 2021 - 2024 Study of inhibitory mechanism of feline infectious peritonitis virus proliferation by calcium antagonist
- 2019 - 2022 Basic research of the relationship between histo-blood group and disease
- 2019 - 2022 イヌAR複合体を起点としたホルモン療法抵抗性前立腺がん診断・治療戦略の創出
- 2018 - 2022 腫瘍におけるBRCA2の変異と結合分子群の機能解明を目的とした新規モデルの作出
- 2016 - 2019 Molecular basis of erythrocyte blood group antigen and its application in association study for disease
- 2014 - 2017 Identification and clinical application of cancer stem cells derived from canine refractory cancers
- 2014 - 2017 Comparative analysis of the interaction of Rad51 recombinase and tumor suppressor BRCA2 aimed at drug development
- 2015 - 2017 Establishment of the new strategy with REIC/Dkk-3 against androgen independent prostate cancer.
- 2012 - 2014 Development of the new strategy targeting for the RAD51 overexpression mammary tumor
- 2011 - 2013 Tumorigenic effects of BRCA2 mutation and genomic instability in dogs
- 2010 - 2011 A search for the interaction molecules with REIC/Dkk-3 in prostate gland.
- 2008 - 2010 Development of rat resources for human models of type 2 diabetes accompanied with obesity.
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Papers (107):
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Zida Zhu, Taisuke Kitano, Masami Morimatsu, Kazuhiko Ochiai, Toshina Ishiguro-Oonuma, Kosuke Oosumi, Xianghui Lin, Koichi Orino, Yasunaga Yoshikawa. A Highly Conserved Region in BRCA2 Suppresses the RAD51-Interaction Activity of BRC Repeats. Veterinary sciences. 2023. 10. 2
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Masanori Kobayashi, Moe Onozawa, Shiho Watanabe, Tomokazu Nagashima, Kyoichi Tamura, Yoshiaki Kubo, Akiko Ikeda, Kazuhiko Ochiai, Masaki Michishita, Makoto Bonkobara, et al. Establishment of a BRAF V595E-mutant canine prostate cancer cell line and the antitumor effects of MEK inhibitors against canine prostate cancer. Veterinary and comparative oncology. 2023. 21. 2. 221-230
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Masaki Michishita, Naoki Hanari, Hitomi Oda, Tomokazu Nagashima, Yukino Machida, Yuji Hamamoto, Kyoichi Tamura, Daigo Azakami, Kazuhiko Ochiai, Akihiro Mori. Pulmonary solid adenocarcinoma in a dog. Journal of Comparative Pathology. 2023. 201. 100-104
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Masaki Michishita, Kazuhiko Ochiai, Rei Nakahira, Daigo Azakami, Yukino Machida, Tomokazu Nagashima, Takayuki Nakagawa, Toshiyuki Ishiwata. mTOR pathway as a potential therapeutic target for cancer stem cells in canine mammary carcinoma. Frontiers in Oncology. 2023. 13. 1100602
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Kei Shimakawa, Kazuhiko Ochiai, Sachi Hirose, Eri Tanabe, Masaki Michishita, Motoharu Sakaue, Yasunaga Yoshikawa, Masami Morimatsu, Tsuyoshi Tajima, Masami Watanabe, et al. Canine Mammary Tumor Cell Lines Derived from Metastatic Foci Show Increased RAD51 Expression but Diminished Radioresistance via p21 Inhibition. Veterinary sciences. 2022. 9. 12
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MISC (33):
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林 香慧, 北野 泰佑, 落合 和彦, 酒井 洋樹, 折野 宏一, 吉川 泰永. ANXA2がイヌ血管肉腫細胞の遊走能に及ぼす影響. 日本獣医学会学術集会講演要旨集. 2022. 165回. [I1P-08]
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兵頭あかね, 町田雪乃, 落合和彦, 落合和彦, 小野沢栄里, 呰上大吾, 道下正貴, 道下正貴. 猫の膵外分泌腺癌株化細胞Fpacc-E由来のsphere形成細胞の特性解析. 日本獣医学会学術集会講演要旨集. 2021. 164th (CD-ROM)
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吉村久志, 山本昌美, 岸本拓也, 岸本拓也, 町田雪乃, 道下正貴, 落合和彦, 中川貴之, 松田陽子, 高橋公正, et al. 犬の乳腺腫瘍におけるnestinの発現と悪性挙動への関与. 日本獣医学会学術集会講演要旨集. 2021. 164th (CD-ROM)
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高木 香奈, 呰上 大吾, 町田 雪乃, 落合 和彦, 道下 正貴. 犬の肺腺癌におけるヒトWHO分類に準拠した亜型分類および予後との関連性. 日本獣医学会学術集会講演要旨集. 2019. 162回. 347-347
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高添 夏希, 町田 雪乃, 野上 英, 原田 知享, 落合 和彦, 呰上 大吾, 道下 正貴. 犬のリンパ腫におけるPKM2発現と臨床病理学的および病理組織学的特徴との関連性. 日本獣医学会学術集会講演要旨集. 2019. 162回. 348-348
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Patents (2):
Lectures and oral presentations (76):
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Relationship between Canine Breed Diversity and Mammary Tumor Pathogenesis Mechanisms
(2022)
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ドラッグリポジショニングを利用した猫伝染性腹膜炎の治療戦略
(第165回日本獣医学会学術集会 2022)
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イオノフォア抗生剤によるネココロナウイルス増殖阻害効果の検討
(第165回日本獣医学会学術集会 2022)
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p53四量体形成ドメイン変異イヌ乳腺腫瘍由来細胞株の性状解析
(第165回日本獣医学会学術集会 2022)
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犬の肺癌オルガノイドを用いた in vitro抗癌剤スク リーニング
(第165回日本獣医学会学術集会 2022)
more...
Education (2):
- - 2005 Gifu University The United Graduate School of Veterinary Sciences
- - 2001 Iwate University Faculty of Agriculture
Professional career (1):
Work history (7):
Association Membership(s) (4):
日本比較臨床医学会
, 日本実験動物学会
, 日本分子生物学会
, 日本獣医学会
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