Research keywords (2):
G protein-coupled receptor
, post-translational modification
Research theme for competitive and other funds (14):
2022 - 2025 蛍光アセチルコリンセンサーによる細胞内コリン伝達系の実証
2019 - 2023 Induction of steroidogenic cells from stem cells based on the regulation of LRH-1 expression
2018 - 2021 Reinforcement of colonic epithelial barrier via mAChR
2019 - 2021 細胞内局在性ムスカリン受容体の生体における機能解析
2016 - 2019 Functional role of intracellular muscarinic receptor for hippocampal adult neurogenesis
2015 - 2018 Induction of ovarian granulosa cells from mesenchymal stem cells for investigating the molecular mechanisms of their development.
2014 - 2016 Evaluation of intracellular GPCR activation by using FRET imaging
2013 - 2016 Maintenance of intestinal barrier function by focal adhesion kinase
2012 - 2015 Novel functions of surface and intracellular muscarinic receptors in central nervous system and stress
2009 - 2011 Analysis for protein SUMOylation in the central synaptic proteins
2009 - 2010 脳スライスからの高感度神経伝達物質遊離測定法の開発と中枢神経薬理学への応用
2008 - 2010 Receptor-operated Ca influx and transmitter release
2010 - α1L型アドレナリン受容体形成の分子機構解明
2010 - Molecular mechanism of a1L adrenoceptor formation
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Papers (51):
Takayoshi Masuoka, Takeshi Kiyoi, Shijie Zheng, Qiang He, Li Liu, Junsuke Uwada, Ikunobu Muramatsu. Corneal acetylcholine regulates sensory nerve activity via nicotinic receptors. The ocular surface. 2024. 32. 60-70
Itsumi Arakawa, Ikunobu Muramatsu, Junsuke Uwada, Kiyonao Sada, Noriyuki Matsukawa, Takayoshi Masuoka. Acetylcholine release from striatal cholinergic interneurons is controlled differently depending on the firing pattern. Journal of neurochemistry. 2023. 167. 1. 38-51
Junsuke Uwada, Hitomi Nakazawa, Ikunobu Muramatsu, Takayoshi Masuoka, Takashi Yazawa. Role of Muscarinic Acetylcholine Receptors in Intestinal Epithelial Homeostasis: Insights for the Treatment of Inflammatory Bowel Disease. International journal of molecular sciences. 2023. 24. 7
Takashi Yazawa, Yoshitaka Imamichi, Takeshi Kitano, Mohammad Sayful Islam, Md Rafiqul Islam Khan, Satoru Takahashi, Toshio Sekiguchi, Nobuo Suzuki, Akihiro Umezawa, Junsuke Uwada. Expression of Chrna9 is regulated by Tbx3 in undifferentiated pluripotent stem cells. Scientific reports. 2023. 13. 1. 1611-1611