Rchr
J-GLOBAL ID:201001048017117523   Update date: Apr. 15, 2024

Shinji Miura

ミウラ シンジ | Shinji Miura
Affiliation and department:
Job title: Professor
Homepage URL  (1): https://www.shizuoka-lnb.com/
Research field  (4): Physiology ,  Nutrition and health science ,  Sports science ,  Metabolism and endocrinology
Research keywords  (13): phospholipids ,  lipidomics ,  transgenic mice ,  PGC-1α ,  skeletal muscle fiber ,  mitochondria ,  physical activity ,  exercise ,  muscular atrophy ,  FOXO1 ,  atherosclerosis ,  lifestyle disease ,  metabolic syndrome
Research theme for competitive and other funds  (16):
  • 2024 - 2027 アシル基転移酵素LPLAT7によるリン脂質のアシル基リモデリングが骨格筋機能を制御する
  • 2022 - 2024 小腸吸収上皮細胞を構成する膜リン脂質による栄養素吸収機能の制御
  • 2021 - 2024 リン脂質の脂肪酸リモデリングによる骨格筋機能調節機構の解明
  • 2019 - 2021 Control of muscle fiber properties by diversity of fatty acid species that bind to phospholipids
  • 2018 - 2021 Increased expression of PGC-1alpha in skeletal muscle suppresses the development of atherosclerosis
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Papers (99):
  • Takumi Sugimoto, Chihiro Sakamaki, Tokushi Kimura, Takahiro Eguchi, Shinji Miura, Yasutomi Kamei. Peroxisome proliferator-activated receptor γ coactivator 1α regulates downstream of tyrosine kinase-7 (Dok-7) expression important for neuromuscular junction formation. Scientific Reports. 2024. 14. 1
  • Akika Nagata, Shiori Oishi, Nanako Kirishita, Keita Onoda, Takuma Kobayashi, Yuko Terada, Akira Minami, Nanami Senoo, Yasukiyo Yoshioka, Kunitoshi Uchida, et al. Allyl Isothiocyanate Maintains DHA-Containing Glycerophospholipids and Ameliorates the Cognitive Function Decline in OVX Mice. ACS omega. 2023. 8. 45. 43118-43129
  • Yuta Ozaki, Koji Ohashi, Naoya Otaka, Hiroshi Kawanishi, Tomonobu Takikawa, Lixin Fang, Kunihiko Takahara, Minako Tatsumi, Sohta Ishihama, Mikito Takefuji, et al. Myonectin protects against skeletal muscle dysfunction in male mice through activation of AMPK/PGC1α pathway. Nature communications. 2023. 14. 1. 4675-4675
  • Tomoki Sato, Shuhei Umebayashi, Nanami Senoo, Takumi Akahori, Hiyori Ichida, Noriyuki Miyoshi, Takuya Yoshida, Yuki Sugiura, Naoko Goto-Inoue, Hiroki Kawana, et al. LPGAT1/LPLAT7 regulates acyl chain profiles at the sn-1 position of phospholipids in murine skeletal muscles. The Journal of biological chemistry. 2023. 299. 7. 104848-104848
  • Katsuya Fukui, Miyuki Nomura, Kazuhiro Kishimoto, Nobuhiro Tanuma, Koreyuki Kurosawa, Kosuke Kanazawa, Hiroyuki Kato, Tomoki Sato, Shinji Miura, Koh Miura, et al. PP6 deficiency in mice with KRAS mutation and Trp53 loss promotes early death by PDAC with cachexia-like features. Cancer science. 2022
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MISC (58):
  • 三浦 進司. 【栄養・代謝物シグナルと食品機能 転写、エピゲノムの制御から代謝性疾患の治療・予防に向けて】(第2章)栄養・代謝物シグナルと臓器連関 運動トレーニングとリン脂質のリモデリング リン脂質クオリティと骨格筋の関係. 実験医学. 2022. 40. 7. 1131-1137
  • 三浦進司. Lipid metabolism in skeletal muscle-Energy source and the function of lipids as a building block of skeletal muscle. 実験医学. 2022. 40. 2. 160-166
  • 妹尾奈波, 三好規之, 守田昭仁, 亀井康富, 三浦進司. PGC-1αは骨格筋においてカルジオリピン生合成を調節する. 脂質生化学研究. 2019. 61. 138-139-139
  • 赤堀拓, 梅林脩平, 妹尾奈波, 佐藤友紀, 佐藤友紀, 三好規之, 吉田卓矢, 守田昭仁, 杉浦悠毅, 井上菜穂子, et al. グリセロリン脂質に結合する脂肪酸種の筋線維タイプ依存的制御とPGC-1αの関与. 脂質生化学研究. 2019. 61. 121-123-123
  • 妹尾奈波, 三浦進司. 骨格筋のリポクオリティ制御. 医学のあゆみ. 2019. 269. 13. 1155-1159
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Patents (13):
Education (3):
  • 1993 - 1996 University of Shizuoka Graduate School of Pharmaceutical Sciences
  • 1989 - 1991 Kyoto Pharmaceutical University Graduate School of Pharmaceutical Sciences
  • 1985 - 1989 Kyoto Pharmaceutical University School of Pharmaceutical Sciences
Professional career (1):
  • Ph.D (University of Shizuoka)
Work history (10):
  • 2014/12 - 現在 University of Shizuoka School of Food and Nutritional Sciences Professor
  • 2012/04 - 2014/11 University of Shizuoka School of Food and Nutritional Sciences Associate Professor
  • 2011/04 - 2012/03 National Institute of Health and Nutrition Head
  • 2006/04 - 2011/03 national Institute of Health and Nutrition Project Leader
  • 2004/04 - 2006/03 National Institute of Health and Nutrition Senior Researcher
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Committee career (18):
  • 2024/04 - 現在 消費者庁 食品衛生規準審議会 臨時委員
  • 2024/04 - 現在 Japan Society of Nutrition and Food Science, Chubu President of a branch office (Chubu)
  • 2024/03 - 現在 The Physiological Society of Japan Council member
  • 2023/04 - 現在 The Physiological Society of Japan Member of the editorial board, J Physiol Sci
  • 2022/04 - 現在 Shizuoka City Board of Education School management council member
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Association Membership(s) (7):
The Physiological Society of Japan ,  Japan Muscle Society ,  The Japanse Biochemical Society ,  THE JAPANESE CONFERENCE ON THE BIOCHEMISTRY OF LIPIDS ,  American Society for Biochemistry and Molecular Biology ,  THE JAPANESE SOCIETY OF PHYSICAL FITNESS AND SPORTS MEDICINE ,  JAPAN SOCIETY OF NUTRITION AND FOOD SCIENCE
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