Research field (6)：
Biomedical engineering
, Fluid engineering
, Medical equipment testing
, Measurement engineering
, Medical systems
, Biomaterials
Research theme for competitive and other funds (32)：
2024 - 2029 Promotion and Multifaceted Development of Clinical Application of Pulmonary Artery Augmentation Using Tissue Engineered Vascular Grafts for Pediatric Heart Diseases
2024 - 2027 Development of short-time decellularization procedure for tissue engineered vascular grafts allotransplantation
2023 - 2026 流体構造練成解析を用いた口腔内装置作成システム
2022 - 2025 Development of a vascular prothesis regenerated in the patient's body using a decellularized xenogeneic cell-free device
2022 - 2025 Attempt to use skin tissue killed by high-pressure treatment technology as autologous regenerative vascular grafts
2020 - 2025 A multifaceted study aiming at expanding the clinical application of autologous in vivo-tissue engineered vascular grafts
2021 - 2024 Development of an Optimal Chemical Processing for Allogeneic In Vivo Tissue Engineered Vascular Grafts
2019 - 2024 Pulmonary artery enlargement for congenital heart disease using connective tissue membrane using in vivo tissue engineering
2020 - 2023 Development of allogeneic in vivo-tissue engineered vascular graft preparation completed in the operating room without using special facilities
2019 - 2022 高圧処理化自家皮膚組織の”自己体内再生型”血管補填材料としての応用
2018 - 2022 Development of an optimal treatment method for using biomaterials as cardiovascular prostheses
2017 - 2021 Development of vascular grafts for auto implantation rapidly formed in patients using xenogeneic decellularized connective tissue tubules as scaffolds
2019 - 2020 下肢動脈バイパス用人工血管作製用の鋳型の仕様決定と事業計画策定
2016 - 2019 Diversified deployment of "self-regenerating" connective tissue vascular grafts "Biotubes" for clinical applications.
2016 - 2019 In vitro experiments on changes of erythrocyte deformability by the blood circulation in the hemodialysis circuit
2015 - 2018 Development of arterial grafts regenerated from the xenogeneic scaffolds
2014 - 2018 Development of cardiovascular grafts constructed by in vivo tissue engineering
2014 - 2017 Development of measurement and evaluation system of erythrocyte deformability embedded into a conventional blood test system
2013 - 2017 Development of Autologous Bitubes for CABG Constructed in the Patients
2013 - 2016 Development of Two-Staged in vivo tissue engineering for xenogeneic implantation of cardiovascular tissues.
2012 - 2015 Development of In vivo tissue engineered autologous tube grafts "Biotubes" for suturess microvascular reconstruction
2012 - 2014 Development of evaluation method for erythrocyte deformability by using micro-TAS(Screening and detection of pathological erythrocytes)
2011 - 2013 Development of prediction and evaluation model of deformability of erythrocyte
2010 - 2012 D.I.Y. Medicine:Development of autologous tissue heart valves constructed in the body of the patient
2007 - 2009 Development of autologous tissue heart valves constructed by in vivo tissue engineering.
2007 - 2008 Multiscale coupled simulation of respiratory system
2007 - 2008 Development of an evaluation methods for the fluid dynamic and the structural dynamic characteristics of human aortic valve and its practical applications
2005 - 2006 Development of blood flow analysis system for total blood through micro-channel in biochip
2003 - 2004 マイクロ流体システムを利用した血液および模擬血液の微小循環特性の解明
2002 - 2004 development of model erythrocyte and creation of artificial erythrocyte by using an electro-hydrodynamic spraying operating in cone-jet mode
2002 - 2004 Research on Optimum Design of Stent Used for Interventional Treatment Apparatus of Aneurysms
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Papers (56)：
Tsutomu Tajikawa, Shimpei Kohri, Taiki Mouri, Takaichi Fujimi, Hiromasa Yamaguchi, Kenkichi Ohba. Development of Miniaturised Fibre-Optic Laser Doppler Velocimetry for Opaque Liquid: Measurement of the Velocity Profile in the Engine Oil Flow of a Lubrication System. Photonics. 2024. 11. 9. 892
Kazuki Mori, Tadashi Umeno, Takayuki Kawashima, Tomoyuki Wada, Takuro Genda, Masanagi Arakura, Yoshifumi Oda, Takayuki Mizoguchi, Ryosuke Iwai, Tsutomu Tajikawa, et al. Breaking the Limit of Cardiovascular Regenerative Medicine: Successful 6-Month Goat Implant in World’s First Ascending Aortic Replacement Using Biotube Blood Vessels. Bioengineering. 2024. 11. 4
Tsutomu Tajikawa, Keita Aoki, Hiroaki Fukuzawa. Mathematical Investigation for the Mechanism of the Pancreatic Juice Reflux in High Confluence of Pancreaticobiliary Ducts and Pancreaticobiliary Maljunction. Biomedical Journal of Scientific & Technical Research. 2024. 55. 5. 47447-47456
Tadashi Umeno, Kazuki Mori, Ryosuke Iwai, Takayuki Kawashima, Takashi Shuto, Yumiko Nakashima, Tsutomu Tajikawa, Yasuhide Nakayama, Shinji Miyamoto. Carotid Artery Bypass Surgery of In-Body Tissue Architecture-Induced Small-Diameter Biotube in a Goat Model: A Pilot Study. Bioengineering. 2024. 11. 3. 203-203
Effect of vascular anastomosis on thrombus and neointima formation during vascular bypass surgery with “Biotube” vascular grafts
(The Proceedings of the JSME Conference on Frontiers in Bioengineering 2022)
Effect of Mechanical Anisotropy of Heart Valves on Hemodynamical Performance: (Evaluation by In Vitro Experimental Simulation)
(The Proceedings of the JSME Conference on Frontiers in Bioengineering 2022)
Effect of mechanical anisotropy in heart valve leaflet on hydrodynamical performance of artificial semilunar valves
(The Proceedings of the Fluids engineering conference 2022)
Development of Artificial Heart Valve with a Membranous Cusp (Influence of Mechanical Anisotropy)
(Transactions of Japanese Society for Medical and Biological Engineering 2021)
2022 - U.S. National Academy of Medicine Healthy Longevity Global Competition, Catalyst Award Development of in-body tissue-engineered autologous vascular grafts (Biotube)
Japanese Society for Laboratory Hematology
, Japanese Society for Biorheology
, Japan Society for Artificial Organs
, Japanese Society for Medical and Biological Engineering
, Visualization society of japan
, Japan society of fluid mechanics
, Japan society of mechanical engineers
