Rchr
J-GLOBAL ID：201001056660960613   Update date: Jun. 11, 2024

Kudo Fumitaka

クドウ フミタカ | Kudo Fumitaka
Affiliation and department：
Tokyo Institute of Technology School of Science

About Tokyo Institute of Technology School of Science


Job title： Associate Professor
Research field  (6)： Applied biochemistry ,  Biochemistry ,  Chemical biology ,  Bioorganic chemistry ,  Structural/physical organic chemistry ,  Molecular biochemistry
Research keywords  (5)： Structural biology ,  Microbiology ,  Enzymology ,  Natural product chemistry ,  Bioorganic chemistry
Research theme for competitive and other funds  (26)：
  • 2021 - 2025 細胞核形成における分子機構についての研究
  • 2019 - 2024 アミノグリコシド系抗生物質の生合成酵素構造解析を基盤とする新規物質生産系の開拓
  • 2017 - 2019 抗腫瘍性マクロライド抗生物質生合成マシナリーのリデザイン
  • 2016 - 2018 Cultivation of Useful Marine Cyanobacteria and Analysis of Biosynthetic genes
  • 2014 - 2017 アミノグリコシド抗生物質の構造多様性の鍵を握るラジカルSAM酵素の精密反応解析
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Papers (110)：
  • Fumitaka Kudo, Kazuma Tsuboi, Mutsumi Ikezaki, Daiki Nagayama, Koichi Kawamura, Taishi Ando, Akimasa Miyanaga, Tadashi Eguchi. The Post-Polyketide Synthase Modification Mechanism in Hitachimycin Biosynthesis. Chembiochem : a European journal of chemical biology. 2024. e202400405
  • Dawei Wang, Akimasa Miyanaga, Taichi Chisuga, Fumitaka Kudo, Tadashi Eguchi. Engineering the Substrate Specificity of (S)-β-Phenylalanine Adenylation Enzyme HitB. Chembiochem : a European journal of chemical biology. 2024. e202400383
  • Akimasa Miyanaga, Kenji Nagata, Joji Nakajima, Taichi Chisuga, Fumitaka Kudo, Tadashi Eguchi. Structural Basis of Amide-Forming Adenylation Enzyme VinM in Vicenistatin Biosynthesis. ACS chemical biology. 2023
  • Taichi Chisuga, Satoshi Murakami, Akimasa Miyanaga, Fumitaka Kudo, Tadashi Eguchi. Structure-Based Analysis of Transient Interactions between Ketosynthase-like Decarboxylase and Acyl Carrier Protein in a Loading Module of Modular Polyketide Synthase. ACS chemical biology. 2023. 18. 6. 1398-1404
  • Fumitaka Kudo, Takuji Chikuma, Mizuki Nambu, Taichi Chisuga, Shimpei Sumimoto, Arihiro Iwasaki, Kiyotake Suenaga, Akimasa Miyanaga, Tadashi Eguchi. Unique Initiation and Termination Mechanisms Involved in the Biosynthesis of a Hybrid Polyketide-Nonribosomal Peptide Lyngbyapeptin B Produced by the Marine Cyanobacterium Moorena bouillonii. ACS chemical biology. 2023. 18. 4. 875-883
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MISC (13)：
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Patents (2)：
  • 酵素法によるD-グルコースから2-デオキシ-scyllo-イノソースの調製法
  • ラクタム及びラクトン合成酵素
Lectures and oral presentations  (65)：
  • Biosynthetic studies of macrocyclic polyketide antibiotics in Actinomycetes
    (The 4th A3 foresight symposium on Chemical & Synthetic Biology of Natural Products 2019)
  • Study on radical SAM C-methyltransferase Fom3 in fosfomycin biosynthesis
    (2nd China-Japan Joint Symposium on Natural Product Biosynthesis 2019)
  • Biosynthesis of macrocyclic polyketide antibiotics
    (RIKEN Center for Sustainable Resource Science Seminar 2018)
  • Biosynthesis of macrocyclic polyketide antibiotics
    ("Department of Life Science and Biochemical Engineering Sun Moon University", Seminar 2018)
  • Biosynthesis of antitumor antibiotic pactamycin
    (The 60th Symposium on the Chemistry of Natural Products 2018)
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Education (2)：
  • 1994 - 1999 Tokyo Institute of Technology Science of Engineering Chemistry
  • 1990 - 1994 Tokyo Institute of Technology School of Science Dept. of Chemistry
Professional career (1)：
  • 理学(博士) (東京工業大学)
Work history (6)：
  • 2016/04 - 現在 Tokyo Institute of Technology School of Science
  • 2010/05 - 2016/03 Tokyo Institute of Technology Graduate School of Science and Engineering, Department of Chemistry
  • 2007/04 - 2010/04 Tokyo Institute of Technology Graduate School of Science and Engineering, Department of Chemistry
  • 2003/03 - 2007/03 Tokyo Institute of Technology Chemistry Research associate
  • 2001/04 - 2003/03 The Johns Hopkins University Chemistry Postdoctoral Fellow
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Awards (8)：
  • 2017 - 東京工業大学 平成27年度 東工大教育賞優秀賞 学部一年生向けのサステイナブルな環境安全教育
  • 2016 - 東京工業大学 2016年度前学期 理学部若手教員教育賞 「学部学生向けの環境安全教育 ~ 安全の化学」
  • 2009 - The 4th Asian Core Program Lectureship Award (from Thailand) (2009) "Biosynthetic Studies of Macrolide Antibiotic FD-891 Produced by Streptomyces graminofaciens A-8890"
  • 2009 - 内藤記念科学振興財団 平成21年度 第25回内藤コンファレンスポスター賞 放線菌由来ポリケチド修飾酵素の機能解析
  • 2008 - The 3rd Asian Core Program Lectureship Award (from Hong Kong) (2008) "Radical SAM Dehydrogenase in the Biosynthesis of Butirosin"
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Association Membership(s) (5)：
The Society of Synthetic Organic Chemistry, Japan ,  The Society for Actinomycetes Japan ,  Japan Society for Bioscience, Biotechnology, and Agrochemistry ,  American Chemical Society ,  The Chemical Society of Japan
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