Rchr
J-GLOBAL ID：201001060380046905   Update date: Sep. 12, 2024

Hiromoto Takeshi

ヒロモト タケシ | Hiromoto Takeshi
Affiliation and department：
National Institutes for Quantum and Radiological Science and Technology Institute for Quantum Life Science

About National Institutes for Quantum and Radiological Science and Technology Institute for Quantum Life Science


Job title： Senior Researcher
Other affiliations (1)：
Research field  (2)： Structural biochemistry ,  Biophysics
Research keywords  (3)： Neutron Crystallography ,  X-ray Crystallography ,  Structural Biology
Research theme for competitive and other funds  (4)：
  • 2019 - 2022 Elucidation of the catalytic mechanism of hydrogenase based on all-atom structure information for the mitigation of global warming
  • 2019 - 2020 中性子により[NiFe]-ヒドロゲナーゼのプロトン輸送経路を可視化する
  • 2018 - 2019 中性子により[NiFe]ヒドロゲナーゼのプロトン輸送経路を可視化する
  • 2017 - 2018 膜結合型[NiFe]ヒドロゲナーゼの組換え体調製とその構造解析
Papers (26)：
  • Takeshi Hiromoto, Koji Nishikawa, Seiya Inoue, Hideaki Ogata, Yuta Hori, Katsuhiro Kusaka, Yu Hirano, Kazuo Kurihara, Yasuteru Shigeta, Taro Tamada, et al. New insights into the oxidation process from neutron and X-ray crystal structures of an O2-sensitive [NiFe]-hydrogenase. Chemical Science. 2023. 14. 35. 9306-9315
  • Toshiaki Nakano, Ken Akamatsu, Masataka Tsuda, Ayane Tujimoto, Ryoichi Hirayama, Takeshi Hiromoto, Taro Tamada, Hiroshi Ide, Naoya Shikazono. Formation of clustered DNA damage in vivo upon irradiation with ionizing radiation: visualization and analysis with atomic force microscopy. Proceedings of the National Academy of Sciences of the United States of America. 2022. 119. 13. e2119132119
  • Takeshi Hiromoto, Teikichi Ikura, Eijiro Honjo, Michael Blaber, Ryota Kuroki, Taro Tamada. Creation of Cross-Linked Crystals With Intermolecular Disulfide Bonds Connecting Symmetry-Related Molecules Allows Retention of Tertiary Structure in Different Solvent Conditions. Frontiers in molecular biosciences. 2022. 9. 908394-908394
  • Katsushiro Miyamoto, Hiroaki Kawano, Naoko Okai, Takeshi Hiromoto, Nao Miyano, Koji Tomoo, Takahiro Tsuchiya, Jun Komano, Tomotaka Tanabe, Tatsuya Funahashi, et al. Iron-Utilization System in Vibrio vulnificus M2799. MARINE DRUGS. 2021. 19. 12
  • Takeshi Hiromoto, Koji Nishikawa, Taro Tamada, Yoshiki Higuchi. The Challenge of Visualizing the Bridging Hydride at the Active Site and Proton Network of [NiFe]-Hydrogenase by Neutron Crystallography. Topics in Catalysis. 2021. 64. 9-12. 622-630
ｍore...
MISC (41)：
  • Taro Tamada, Takeshi Hiromoto. Elucidation of Enzymatic Catalytic Reaction by Neutron Crystallography. Catalysts and Catalysis. 2024. 66. 4. 216-221
  • 廣本武史, 西川幸志, 樋口芳樹, 玉田太郎. 中性子結晶構造解析を用いたヒドロゲナーゼ酸化型における特徴的な水素結合の観察. 日本結晶学会年会講演要旨集. 2023. 2023
  • 玉田太郎, 平野優, 廣本武史, 栗原和男. 量研で実施している中性子結晶構造解析の現状. 日本結晶学会年会講演要旨集. 2023. 2023
  • 栗原和男, 平野優, 廣本武史, 河野史明, 田村格良, 玉田太郎. Updating of neutron diffractometers for protein crystals, BIX-3 and BIX-4. 日本中性子科学会年会講演概要集. 2022. 22nd
  • 玉田太郎, 平野優, 廣本武史, 栗原和男. 生体高分子用中性子単結晶回折装置BIX-3,4の現状. 日本結晶学会年会講演要旨集. 2022. 2022
ｍore...
Education (1)：
  • 2002 - 2005 Kwansei Gakuin University Graduate School of Science Department of Chemistry
Professional career (1)：
  • Doctor of Science (Kwansei Gakuin University)
Work history (10)：
  • 2019/04 - 現在 National Institutes for Quantum and Radiological Science and Technology Institute for Quantum Life Science Seniro Researcher
  • 2016/04 - 2019/03 University of Hyogo Graduate School of Life Science SA Associate Professor
  • 2016/02 - 2016/04 University of Hyogo Graduate School of Life Science SA Assistant Professor
  • 2013/02 - 2016/01 Japan Atomic Energy Agency Quantum Beam Science Center Resercher
  • 2012/08 - 2016/01 SOSHO, Inc. Crystallization team Researcher
Show all
Association Membership(s) (2)：
THE CRYSTALLOGRAPHIC SOCIETY OF JAPAN ,  PROTEIN SCIENCE SOCIETY OF JAPAN
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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