Takahashi Chiaki

タカハシチアキ | Takahashi Chiaki

Affiliation and department：
Homepage URL (2)： http://omb.w3.kanazawa-u.ac.jp/index.html , http://www.kanazawa-u.ac.jp/~ganken/index.html

Research field (2)： Tumor biology , Pathobiochemistry

Research keywords (6)：腫瘍遺伝学 , 分子生物学 , 分子腫瘍学 , Cancer Genetics , Molecular Biology , Molecular Oncology

Research theme for competitive and other funds (21)：

2020 - 2024 RB1 tumor suppressor functions in metabolism
2019 - 2022 Analysis of DIP2C as a novel regulator for epithelial-mesenchymal transition of rheumatoid arthritis synovium and a potential therapeutic target
2019 - 2021 Drug development targeting metabolic vulnerability associated with SUCLA2 loss
2017 - 2020 Metabolic regulation by RB tumor suppressor gene
2017 - 2019 Drug discovery based on collateral lethality

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Papers (94)：

Hai Yu, Susumu Kohno, Dominic Chih-Cheng Voon, Nada Hamdy Hussein, Yuanyuan Zhang, Joji Nakayama, Yujiro Takegami, Chiaki Takahashi. RECK/GPR124-driven WNT signaling in pancreatic and gastric cancer cells. Cancer Science. 2024
Kayo Kayahashi, Mahadi Hasan, Anowara Khatun, Susumu Kohno, Jumpei Terakawa, Shin-Ichi Horike, Natsumi Toyoda, Ayumi Matsuoka, Takashi Iizuka, Takeshi Obata, et al. Androgen-responsive FOXP4 is a target for endometrial carcinoma. Communications biology. 2024. 7. 1. 740-740
Linxiang Gong, Dominic Chih-Cheng Voon, Joji Nakayama, Chiaki Takahashi, Susumu Kohno. RB1 loss induces quiescent state through downregulation of RAS signaling in mammary epithelial cells. Cancer Science. 2024. 115. 5. 1576-1586
上原将大, 竹中哲, 堂本貴寛, 堀家慎一, 高橋智聡, 宮下知治, 源利成. ゲムシタビン耐性膵がんにおけるCyclin D2の過剰発現と治療標的としての可能性(Overexpression of Cyclin D2 in Gemcitabine-Resistant Pancreatic Cancer and its Potential as a Therapeutic Target). 日本癌学会総会記事. 2023. 82回. 336-336
Nobuhiro Okada, Chihiro Ueki, Masahiro Shimazaki, Goki Tsujimoto, Susumu Kohno, Hayato Muranaka, Kiyotsugu Yoshikawa, Chiaki Takahashi. NFYA promotes malignant behavior of triple-negative breast cancer in mice through the regulation of lipid metabolism. Communications biology. 2023. 6. 1. 596-596

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MISC (41)：

岡橋伸幸, 島知輝, 近藤佑哉, 荒木千絵, 辻周真, 澤井茜, 上原ひかる, 河野晋, 清水浩, 高橋智聡, et al. Association of aerobic glycolysis and metabolic heat in cultured cancer cells. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
Which intercellular interaction should be targeted in cancer therapy?. 2020. 274. 5. 469-473
盛金丹, 高橋智聡, 河野晋, 岡田宣宏. キナーゼ阻害剤と組み合わせたCDK4/6阻害剤によるHCCの新しい併用療法. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
Chiaki Takahashi, Susumu Kohno. Control of undifferentiated behavior of cancer cells by RB1. 2020. 273. 5. 410-414
Fengkai Li, Shunsuke Kitajima, Naofumi Mukaida, Chiaki Takahashi. Rb inactivation enhances tumor progression by elevating CCL2 expression. CYTOKINE. 2017. 100. 189-190

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Education (2)：

1992 - 1996 Kyoto University
1984 - 1990 Kyoto University Faculty of Medicine

Professional career (1)：

MD., Ph. D., (Kyoto University)

Work history (9)：

2011/04 - 現在 Kanazawa University Cancer Research Institute
2009/12 - 2011/03 金沢大学がん研究所教授
2008/04 - 2009/11 京都大学医学研究科研究員
2004/01 - 2008/03 Kyoto University Graduate School of Medicine
1996/06 - 2003/12 Kyoto University Graduate School of Medicine

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Committee career (3)：

- 現在日本癌学会評議員
2015 - 2016 AMED プログラムオフィサー
2007 - 2011 日本病態プロテアーゼ学会評議員

Awards (1)：

2004 - 日本癌学会奨励賞

Association Membership(s) (8)：

AACR , 日本癌治療学会 , ASBMB , JAPAN SOCIETY FOR CELL BIOLOGY , THE JAPANESE SOCIETY OF INTERNAL MEDICINE , THE JAPANESE BIOCHEMICAL SOCIETY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE CANCER ASSOCIATION

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