Katsuya Sakai

サカイカツヤ | Katsuya Sakai

Affiliation and department：
Other affiliations (1)：

Research field (4)： Functional biochemistry , Applied biochemistry , Medical biochemistry , Tumor biology

Research keywords (4)： Receptor , Cancer , Chemical biology , Growth factor

Research theme for competitive and other funds (11)：

Show all

Papers (59)：

Nichole Marcela Rojas-Chaverra, Ryu Imamura, Hiroki Sato, Toby Passioura, Emiko Mihara, Tatsunori Nishimura, Junichi Takagi, Hiroaki Suga, Kunio Matsumoto, Katsuya Sakai. A cyclic peptide-grafted Fc with hepatocyte growth factor functionality ameliorates hepatic fibrosis in a non-alcoholic steatohepatitis mouse model. iScience. 2024
Katsuya Sakai, Hiroki Sato, Kunio Matsumoto. Cytokine Mimetics with Various Modalities. Israel Journal of Chemistry. 2024
Ryu Imamura, Hiroki Sato, Dominic Chih-Cheng Voon, Takayoshi Shirasaki, Masao Honda, Makoto Kurachi, Katsuya Sakai, Kunio Matsumoto. Met receptor is essential for MAVS-mediated antiviral innate immunity in epithelial cells independent of its kinase activity. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 40. e2307318120
Junichi Taira, Miho Yamaguchi, Anju Tashiro, Asuka Kida, Ko Suzuki, Katsuya Sakai, Kunio Matsumoto, Shunsuke Aoki. Computer-Assisted Identification of Inhibitor with Novel Pharmacophore Targeting First Kringle Domain of Hepatocyte Growth Factor. ChemistrySelect. 2023. 8. 36
Katsuya Sakai, Nozomi Sugano-Nakamura, Emiko Mihara, Nichole Marcela Rojas-Chaverra, Sayako Watanabe, Hiroki Sato, Ryu Imamura, Dominic Chih-Cheng Voon, Itsuki Sakai, Chihiro Yamasaki, et al. Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions. Nature biomedical engineering. 2023. 7. 2. 164-176

ｍore...

MISC (3)：

Hiroki Sato, Ryu Imamura, Katsuya Sakai, Hiroko Oshima, Masanobu Oshima, Kazuhiro Murakami, Yumi Terakado, Yukinari Kato, Seiji Yano, Kunio Matsumoto. Roles of Mature HGF in Gastric Tissue Regeneration and Tumorigenesis. CANCER SCIENCE. 2021. 112. 422-422
藁科翔太, 佐藤拓輝, 造田真希, 酒井克也, PASSIOURA Toby, 和田康弘, 菅裕明, 松本邦夫, 渡辺恭良, 向井英史, et al. Development of a macrocyclic peptide PET probe for activated HGF molecular imaging aimed at cancer precision diagnosis. JSMI Report. 2021. 14. 1
Michikoshi Hiromitsu, Nakamura Takahiro, Sakai Katsuya, Matsumoto Kunio, Matsugo Seiichi. 4Ha01 Inhibition of Growth and Met/HGF Receptor Activation in Human Lung Cancer Cells by Lipoic Acid. 2012. 64. 229-229

Patents (3)：

Books (3)：

Lectures and oral presentations (6)：

ラッソグラフトを用いた人工成長因子による治療可能性の拡大
(第18回霊長類医科学フォーラム 2022)
Receptor agonists generated by lasso-grafting of peptide pharmacophore on Fc for the treatment of tissue injuries
(2021)
Artificial Met agonists based on macrocyclic peptides and protein engineering
(The 15th International Symposium of the Institute Network for Biomedical Sciences 2020 2020)
Artificial Regulation and Structural Basis of MET Receptor
(2020)
Peptide-grafted Proteins and Nanometorology for Targeting and Understanding of Growth Factor Receptor
(2020)

ｍore...

Education (3)：

Professional career (1)：

Work history (6)：

2020/09 - 現在 Kanazawa University Cancer Research Institute・WPI-NanoLSI Associate Professor
2017/10 - 現在 Kanazawa University
2010/04 - 2020/09 Kanazawa University Cancer Research Institute
2008/04 - 2010/03 Osaka University Center for Advanced Science and Innovation
2003/12 - 2008/03 Osaka University

Show all

Awards (4)：

Association Membership(s) (4)：

THE JAPANESE CANCER ASSOCIATION , THE JAPANESE BIOCHEMICAL SOCIETY , 肝細胞研究会 , 十全医学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page