Rchr
J-GLOBAL ID：201001088967371177   Update date: Oct. 23, 2024

MATSUOKA Hiroshi

マツオカ ヒロシ | MATSUOKA Hiroshi
Affiliation and department：
Fukuyama University Faculty of Pharmacy and Pharmaceutical Sciences

About Fukuyama University Faculty of Pharmacy and Pharmaceutical Sciences


Job title： Associate Professor
Other affiliations (1)：
Homepage URL  (2)： https://www.fukuyama-u.ac.jp/pharm/pharmacy/labo-list/genome/ ,  https://www.researchgate.net/profile/Hiroshi_Matsuoka7
Research field  (5)： Metabolism and endocrinology ,  Nutrition and health science ,  Experimental pathology ,  Genomics ,  Molecular biology
Research keywords  (20)： Arteriosclerosis ,  Stroke ,  Inflammation ,  Angiogenesis ,  Cell adhesion ,  Lipid metabolism ,  Hypoxia ,  Transcriptional regulation ,  Nuclear receptor ,  Agonist ,  natural compounds ,  Genetic polymorphism ,  Macrophages ,  Cholesterol ,  Vitamin D ,  flavonoid ,  Transcriptome ,  microRNA ,  Alternative splicing ,  docking simulation
Research theme for competitive and other funds  (4)：
  • 2024 - 2027 Exploration of Agonistic Ligands for Nuclear Receptors and Their Application in Atherosclerosis Treatment
  • 2021 - 2024 Analysis of transcriptional network for nuclear receptor involved in atherosclerosis suppression and its application for drug discovery
  • 2021 - 2022 核内受容体を標的とした血管疾患の新規治療法の確立
  • 2018 - 2020 動脈硬化抑制に寄与する核内受容体の標的因子の網羅的探索
Papers (32)：
  • Akihiro Michihara, Hiroshi Matsuoka, Junichi Fujii, Chiharu Furukawa, Xianting Lin, Jianzhong Yang. Hinokitiol and pyrrolidone carboxylate zinc or corn oligosaccharides: A Synergistic approach to combating scalp microorganisms in seborrheic dermatitis. Fundamental Toxicological Sciences. 2024. 11. 5. 233-241
  • Hiroshi Matsuoka, Akihiro Michihara. Nuclear receptor RORα as a target molecule for the treatment of atherosclerosis. Medical Science Digest (Invited Review). 2024. 50. 6. 32-33
  • Hiroshi Matsuoka, Junichi Fujii, Yuka Nagatsuka, Masaya Ohta, Takashi Sugimoto, Yuhki Sato, Akihiro Michihara. Inhibitory effect of mozuku seaweed-derived ultra-high-molecular-weight fucoidan on the growth of indigenous skin bacteria. Fundamental Toxicological Sciences. 2023. 10. 8. 325-333
  • Hiroshi Matsuoka. Identification of target genes for retinoid-related orphan receptors involved in the suppression of atherosclerosis. Yakugaku Zasshi (Review for Award). 2023. 143. 1. 27-36
  • Akihiro Michihara, Risa Yoshioka, Hiroshi Matsuoka, Marin Kosako, Hinako Fukasaka, Tomomi Nishie. Practice of Test-Linked Illustrative Video Lectures for Genome Education among Elementary School Students in Senior Grades and Evaluation of its Effectiveness. Japanese Journal of social pharmacy. 2022. 41. 2. 125-132
ｍore...
MISC (4)：
  • Education activity on the prevention of disease using genetic analysis. 2018. 36. 45-46
  • The retinoic acid receptor-related orphan receptor α positively regulates tight junction protein claudin domain-containing 1 mRNA expression in human brain endothelial cells. 2018. 36. 43-44
  • Claudin domain containing 1 contributing to endothelial cell adhesion decreases in presence of cerebellar hemorrhage. 2018. 36. 54-55
  • Phosphoenolpyruvate carboxykinase, a key enzyme that controls blood glucose, is a target of retinoic acid receptor-related orphan receptor a. 2017. 35. 55-55
Books (1)：
  • Genetic engineering
    Hirokawa Publishing INC. 2017 ISBN:4567450205
Lectures and oral presentations  (102)：
  • 神経変性疾患に関与するCYP39A1の新規転写調節機構 [28E-09-30]【※学生発表奨励賞受賞】
    (第62回 日本薬学会中国四国学術大会(高知) 2023)
  • ヒドロキシコレステロール代謝調節に係わるRORα核内受容体による作動性リガンドの探索 [28E-09-40]【※学生発表奨励賞受賞】
    (第62回 日本薬学会中国四国学術大会(高知) 2023)
  • 核内受容体を標的とした血管疾患の新規治療法の確立 ~RORα作動性リガンドによる創薬を目指して~
    (2023年度 福山大学研究成果発表会(福山) 2023)
  • レチノイン酸受容体関連オーファン受容体αはマクロファージにおけるコレステロールエステル水解酵素を発現誘導させて脂肪滴形成を縮小させる [27P1-am1-063]
    (第143回日本薬学会年会(札幌) 2023)
  • 脳卒中易発症ラットにおいて量的変化を示すスクワレンエポキシダーゼの新規活性測定法の開発 [6G-10-30]
    (第61回 日本薬学会中国四国学術大会(広島) 2022)
ｍore...
Works (5)：
  • 脂質異常症における細胞接着分子の役割についての研究
    2014 - 現在
  • 動脈硬化抑制に関わる核内受容体RORαの標的遺伝子の探索
    2009 - 現在
  • 福山大学グリーンサイエンス研究センタープロジェクト『生活習慣病の新たな治療方法の開発を目指した脂質輸送と細胞機能の関連性の解明』
    2015 - 2018
  • NEDOプロジェクト『厨房排水処理用油脂分解バイオフィルムの高機能化・安定化のための微生物製剤導入技術の研究開発事業』
    2008 - 2009
  • 枯草菌の脂肪酸分解系レギュロンの機能解析
    2005 - 2008
Professional career (1)：
  • Ph.D.
Work history (5)：
  • 2021/04 - 現在 Fukuyama University Faculty of Pharmacy and Pharmaceutical Sciences Associate professor
  • 2018/04 - 現在 Fukuyama City Medical Association College of Nursing
  • 2013/04 - 2021/03 Fukuyama University Faculty of Pharmacy and Pharmaceutical Sciences
  • 2009/04 - 2013/03 Fukuyama University Faculty of Pharmacy and Pharmaceutical Sciences
  • 2008/05 - 2009/03 Nagoya Institute of Technology
Committee career (1)：
  • 2020/08 - 現在 MDPI journals / Cells - Topical Advisory Panel
Awards (1)：
  • 2021/10 - [The Pharmaceutical Society of Japan, Chugoku-Shikoku Branch] [Award for Young Scientists]
Association Membership(s) (7)：
JAPAN SOCIETY FOR PHARMACEUTICAL EDUCATION ,  JAPAN ATHEROSCLEROSIS SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  JAPAN HEALTH MEDICINE ASSOCIATION ,  SOCIETY OF GENOME MICROBIOLOGY, JAPAN ,  JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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