Rchr
J-GLOBAL ID:201001090802039113   Update date: Sep. 21, 2024

Shinsuke Niwa

ニワシンスケ | Shinsuke Niwa
Affiliation and department:
Homepage URL  (1): http://www.fris.tohoku.ac.jp/~niwa/
Research field  (1): Cell biology
Research keywords  (5): 微小管 ,  分子モーター ,  細胞生物学 ,  神経細胞 ,  細胞骨格
Research theme for competitive and other funds  (17):
  • 2023 - 2026 シナプス小胞の逆行性軸索輸送機構の統合的解析
  • 2022 - 2024 軸索輸送モーターKIF5Aによる長距離輸送機構と疾患のクロススケール解析
  • 2020 - 2023 The molecular mechanism of KIF1A Associated Neurological Disorders
  • 2020 - 2022 In vitro reconstitution of intraflagellar transport by cytoplasmic dynein-2
  • 2019 - 2021 シナプスのスクラップ&ビルドを抑制する新規ARL8サプレッサー遺伝子群の同定
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Papers (49):
  • Rei Iguchi, Tomoki Kita, Taisei Watanabe, Kyoko Chiba, Shinsuke Niwa. Characterizing human KIF1Bß motor activity by single-molecule motility assays and Caenorhabtidis elegans genetics. Journal of cell science. 2024
  • Shinsuke Niwa, Taisei Watanabe, Kyoko Chiba. The FHA domain is essential for the autoinhibition of KIF1A/UNC-104. Journal of cell science. 2024
  • Xiaojiang Guo, Calvin H Huang, Takashi Akagi, Shinsuke Niwa, Richard J McKenney, Ji-Rui Wang, Yuh-Ru Julie Lee, Bo Liu. An Arabidopsis Kinesin-14D motor is associated with midzone microtubules for spindle morphogenesis. Current biology : CB. 2024. 34. 16. 3747-3762
  • Shinsuke Niwa, Natsuki Furusaki, Tomoki Kita, Kyoko Chiba. The chromokinesin Kid forms a homodimer and moves processively along microtubules. 2024
  • Hiroyuki Obinata, Hironori Takahashi, Satoshi Shimo, Toshiyuki Oda, Asako Sugimoto, Shinsuke Niwa. SLC-25A46 Regulates Mitochondrial Fusion through FZO-1/Mitofusin and is Essential for Maintaining Neuronal Morphology. 2024
more...
MISC (3):
Books (1):
  • ブレインサイエンスレビュー2019
    2019
Lectures and oral presentations  (24):
  • The FHA domain is essential for the autoinhibition of KIF1A
    (Cell Bio 2023 2023)
  • Elucidation of KIF1A Associated Neurological Disorder(KAND) pathogenesis and the search for therapeutic target using C. elegans nerves
    (2023)
  • Modeling the motion of heterodimeric motors uncovers head-head coordination in a KIF1A dimer
    (2023)
  • Activation of KIF1A/UNC-104 motor and its involvement in synaptogenesis and neurological disorders
    (Cytoskeleton in Neuron and Glia 2023)
  • Increased and Decreased axonal transport of synaptic precursors is associated with neurological disorders
    (Tohoku Neurotech Symposium 2023 2023)
more...
Education (3):
  • 2001 - 2007 東京大学大学院 医学系研究科 細胞生物学教室
  • 1999 - 2001 The University of Tokyo Faculty of Science Department of Biological Sciences
  • 1997 - 1999 The University of Tokyo
Professional career (1):
  • 博士(医学) (東京大学)
Work history (5):
  • 2019/04 - 現在 Tohoku University Frontier Research Institute for Interdisciplinary Sciences
  • 2018/06 - 2019/02 カリフォルニア大学デイビス校 客員助教授
  • 2015/04 - 2018/03 Tohoku University Frontier Research Institute for Interdisciplinary Sciences
  • 2012/09 - 2015/03 スタンフォード大学 Visiting Scholar (Kang Shen 研究室)
  • 2007/04 - 2012/08 東京大学医学系研究科 研究員 (廣川信隆 研究室)
Committee career (3):
  • 2023 - 2024 EMBO|EMBLシンポジウム「Microtubules: from atoms to complex systems」 オーガナイザー
  • 2023 - 内藤記念科学振興財団 第49回内藤コンファレンス組織委員
  • 2016 - 2017/06 日本細胞生物学会 第68回大会プログラム委員
Awards (3):
  • 2018/04 - 文部科学省 文部科学大臣表彰若手科学者賞
  • 2014/03 - 日本解剖学会 日本解剖学会奨励賞
  • 2013/06 - 日本細胞生物学会 優秀発表賞
Association Membership(s) (3):
American Society for Cell Biology ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  JAPAN SOCIETY FOR CELL BIOLOGY
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