Shinsuke Niwa

ニワシンスケ | Shinsuke Niwa

Affiliation and department：
Homepage URL (1)： http://www.fris.tohoku.ac.jp/~niwa/

Research field (1)： Cell biology

Research keywords (5)：微小管 , 分子モーター , 細胞生物学 , 神経細胞 , 細胞骨格

Research theme for competitive and other funds (17)：

2023 - 2026 シナプス小胞の逆行性軸索輸送機構の統合的解析
2022 - 2024 軸索輸送モーターKIF5Aによる長距離輸送機構と疾患のクロススケール解析
2020 - 2023 The molecular mechanism of KIF1A Associated Neurological Disorders
2020 - 2022 In vitro reconstitution of intraflagellar transport by cytoplasmic dynein-2
2019 - 2021 シナプスのスクラップ&ビルドを抑制する新規ARL8サプレッサー遺伝子群の同定

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Papers (49)：

Rei Iguchi, Tomoki Kita, Taisei Watanabe, Kyoko Chiba, Shinsuke Niwa. Characterizing human KIF1Bß motor activity by single-molecule motility assays and Caenorhabtidis elegans genetics. Journal of cell science. 2024
Shinsuke Niwa, Taisei Watanabe, Kyoko Chiba. The FHA domain is essential for the autoinhibition of KIF1A/UNC-104. Journal of cell science. 2024
Xiaojiang Guo, Calvin H Huang, Takashi Akagi, Shinsuke Niwa, Richard J McKenney, Ji-Rui Wang, Yuh-Ru Julie Lee, Bo Liu. An Arabidopsis Kinesin-14D motor is associated with midzone microtubules for spindle morphogenesis. Current biology : CB. 2024. 34. 16. 3747-3762
Shinsuke Niwa, Natsuki Furusaki, Tomoki Kita, Kyoko Chiba. The chromokinesin Kid forms a homodimer and moves processively along microtubules. 2024
Hiroyuki Obinata, Hironori Takahashi, Satoshi Shimo, Toshiyuki Oda, Asako Sugimoto, Shinsuke Niwa. SLC-25A46 Regulates Mitochondrial Fusion through FZO-1/Mitofusin and is Essential for Maintaining Neuronal Morphology. 2024

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MISC (3)：

Kumiko Hayashi, Shin Hasegawa, Shinsuke Niwa. What is the temperature of a cell?. Europhysics News. 2020. 51. 5. 48-50
Kumiko Hayashi, Shiori Matsumoto, Miki G Miyamoto, Shinsuke Niwa. Physical parameters describing neuronal cargo transport by kinesin UNC-104. Biophysical reviews. 2019. 11. 3. 471-482
丹羽伸介, 廣川信隆. KIF19Aは線毛の長さを制御する微小管脱重合キネシンである. ライフサイエンス新着論文レビュー. 2012

Books (1)：

Lectures and oral presentations (24)：

The FHA domain is essential for the autoinhibition of KIF1A
(Cell Bio 2023 2023)
Elucidation of KIF1A Associated Neurological Disorder(KAND) pathogenesis and the search for therapeutic target using C. elegans nerves
(2023)
Modeling the motion of heterodimeric motors uncovers head-head coordination in a KIF1A dimer
(2023)
Activation of KIF1A/UNC-104 motor and its involvement in synaptogenesis and neurological disorders
(Cytoskeleton in Neuron and Glia 2023)
Increased and Decreased axonal transport of synaptic precursors is associated with neurological disorders
(Tohoku Neurotech Symposium 2023 2023)

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Education (3)：

2001 - 2007 東京大学大学院医学系研究科細胞生物学教室
1999 - 2001 The University of Tokyo Faculty of Science Department of Biological Sciences
1997 - 1999 The University of Tokyo

Professional career (1)：

Work history (5)：

2019/04 - 現在 Tohoku University Frontier Research Institute for Interdisciplinary Sciences
2018/06 - 2019/02 カリフォルニア大学デイビス校客員助教授
2015/04 - 2018/03 Tohoku University Frontier Research Institute for Interdisciplinary Sciences
2012/09 - 2015/03 スタンフォード大学 Visiting Scholar (Kang Shen 研究室)
2007/04 - 2012/08 東京大学医学系研究科研究員 (廣川信隆研究室)

Committee career (3)：

Awards (3)：

Association Membership(s) (3)：

American Society for Cell Biology , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , JAPAN SOCIETY FOR CELL BIOLOGY

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