Takata Fuyuko

タカタフユコ | Takata Fuyuko

Affiliation and department：

Research field (3)： Pharmaceuticals - health and biochemistry , Pharmacology , Clinical pharmacy

Research keywords (8)： diabetes mellitus , obesity , brain inflammation , posttraumatic brain epilepsy , パーキンソン病 , traumatic brain injury , blood brain barrier , brain pericyte

Research theme for competitive and other funds (14)：

2023 - 2026 Chronotherapeutic strategy for Parkinson's disease by intranasal administration of human iPS-derived brain pericytes
2022 - 2026 Novel Therapeutic Strategies through Pericyte Modulation and Apoptosis Prevention in Acute Encephalopathy
2021 - 2024 病変型脳ペリサイトのαシヌクレイン処理能障害による頭部外傷後のパーキンソン病発症
2019 - 2022 Involvement of activated brain pericytes induced by inflammatory bowel disease in the increased aggregation of alpha-synuclein in the brain.
2018 - 2021 The role of pericytes in the development of epileptogenesis after traumatic brain injury

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Papers (55)：

Takuro Iwao, Fuyuko Takata, Junichi Matsumoto, Yuki Goto, Hisataka Aridome, Miho Yasunaga, Miki Yokoya, Yasufumi Kataoka, Shinya Dohgu. Senescence in brain pericytes attenuates blood-brain barrier function in vitro: A comparison of serially passaged and isolated pericytes from aged rat brains. Biochemical and biophysical research communications. 2023. 645. 154-163
Takuro Iwao, Fuyuko Takata, Junichi Matsumoto, Hisataka Aridome, Miho Yasunaga, Miki Yokoya, Yasufumi Kataoka, Shinya Dohgu. Aging decreases docosahexaenoic acid transport across the blood-brain barrier in C57BL/6J mice. PloS one. 2023. 18. 2. e0281946
αシヌクレインによる血液脳関門障害. 2022. 40. 12. 1599-1601
頭部外傷後の脳ペリサイト応答異常と血液脳関門障害. CLINICAL NEUROSCIENCE. 2022. 40. 12. 1568-1570
Taira Matsuo, Rie Komori, Minami Nakatani, Shiori Ochi, Aya Yokota-Nakatsuma, Junichi Matsumoto, Fuyuko Takata, Shinya Dohgu, Yasuhiro Ishihara, Kouichi Itoh. Levetiracetam Suppresses the Infiltration of Neutrophils and Monocytes and Downregulates Many Inflammatory Cytokines during Epileptogenesis in Pilocarpine-Induced Status Epilepticus Mice. International journal of molecular sciences. 2022. 23. 14

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MISC (3)：

Kousuke Matsumoto, Shinya Dohgu, Fuyuko Takata, Junichi Matsumoto, Natsuko Ichiki, Sayaka Tao, Haruki Miyaji, Tsuyoshi Nishioku, Hideki Shuto, Atsushi Yamauchi, et al. Reactive oxygen species (ROS)-mediated regulation of MMP-9 expression in the brain pericytes. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2010. 112. 189P-189P
Koji Sueishi, Kayoko Fujishita, Kaoru Nasu-Tada, Fuyuko Takata, Yasufumi Kataoka, Schuichi Koizumi. Release of matrix metalloproteinase-9 from pericytes via ATP/P2 receptor-mediated signals. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2007. 103. 192P-192P
小泉修一, 藤下加代子, 末石浩二, 末石浩二, 道具伸也, 高田芙友子, DELI Maria A., DELI Maria A., 井上和秀, 片岡泰文, et al. 血液脳関門(BBB)を標的とした創薬 ATP. 生体機能と創薬シンポジウム. 2006. 2006

Books (2)：

Inflammatory Mediators Released by Brain Pericytes as Sensors and Effectors in Blood-Brain Barrier Dysfunction
Humana Press 2021
Biochemical Approaches for Glutamatergic Neurotransmission Measurement of Astrocytic Glutamate Release Using Genetically Encoded Probe Combined with TIRF Microscopy
Humana Press 2018 ISBN:9781493972272

Lectures and oral presentations (142)：

加熱式たばこPloom TECH®抽出物が脳血管内皮細胞のトランスポーター発現と細胞内情報伝達におよぼす影響
(日本薬学会第142年会 2022)
BMP拮抗物質nogginは頭部外傷によるfibrinogen脳内漏出を抑制する
(日本薬学会第142年会 2022)
Aging-induced changes in mRNA expression of dopaminergic neuronrelated genes in C57BL/6 mouse brain
(第95回日本薬理学会年会 2022)
Senescent brain pericytes induced BBB dysfunction by their senescence associated secretory phenotype
(第95回日本薬理学会年会 2022)
Decreased brain uptake of cyclosporin A and tacrolimus in the inflammatory bowel disease mice.
(第95回日本薬理学会年会 2022)

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Education (1)：

2004 - 2007 Fukuoka University Graduate School, Division of Pharmaceutical Sciences

Professional career (1)：

博士(薬学) (福岡大学)

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