Research theme for competitive and other funds (16):
2020 - 2022 Development of Human Disease Model of Arrhythmogenic Right Ventricular Cardiomyopathy for Personalized Medicine
2019 - 2022 Therapeutic development targeting molecular basis of dilated-phase hypertrophic cardiomyopathy
2018 - 2021 Clarification of molecular pathophysiology and identification of therapeutic target in desmosome-related cardiomyopathy
2018 - 2020 Development of upstream therapy targeting molecular basis of refractory cardiomyopathy
2017 - 2020 Usefulness of risk stratification of the patients with heart failure with preserved ejection fraction by multiple biomarkers
2016 - 2019 Therapeutic Application of Genome Editing for Advanced Heart Failure
2015 - 2018 Integrated analyses of mitochondria degradation system as a novel therapeutic target of heart failure
2015 - 2018 Regulatory mechanism of mitochondria dynamics during progression of cardiac reverse remodeling
2014 - 2017 Clarification of the role of regulatory mechanism of mitochondria DNA in heart and the application to treatment of heart failure
2011 - 2014 Elucidation of mechanism of chronic inflammation originated from mitochondria, and the application for the treatment of heart failure
2009 - 2011 Role of intracellular degradation systems in genesis of heart failure
2008 - 2009 The investigation of the role of protein degradation pathway during progression to heart failure, and the application to heart failure treatment.
2007 - 2008 Elucidation of molecular mechanisms underlying cell death in heart failure
2006 - 2007 心筋TNF-αの産生制御機構の心不全発症における役割の解明と治療への応用
心不全の分子生物学的機構に関する研究
Study on the molecularbiological mechanism of heart failure
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Papers (221):
Yuki Matsuoka, Yohei Sotomi, Shungo Hikoso, Akihiro Sunaga, Daisaku Nakatani, Katsuki Okada, Tomoharu Dohi, Taiki Sato, Hirota Kida, Daisuke Sakamoto, et al. Extensive ablation for elderly patients with persistent atrial fibrillation: insights from the EARNEST-PVI prospective randomized trial. Journal of cardiology. 2024
Masami Nishino, Yasuyuki Egami, Hiroaki Nohara, Shodai Kawanami, Kohei Ukita, Akito Kawamura, Koji Yasumoto, Naotaka Okamoto, Yasuharu Matsunaga-Lee, Masamichi Yano, et al. Impact of 12-Month Angioscopic Thrombi and Yellow Plaque After Drug-Eluting Stent Implantation. Circulation journal : official journal of the Japanese Circulation Society. 2024
Yohei Sotomi, Toshiyuki Nagai, Shungo Hikoso, Tsutomu Yoshikawa, Yoshihiko Saito, Kazuhiro Yamamoto, Yoshio Yasumura, Takahisa Yamada, Toshihisa Anzai, Yasushi Sakata. Phenotypic Characteristics of Acute Decompensated Heart Failure With Preserved Ejection Fraction in Japanese Population. JACC. Asia. 2024. 4. 7. 566-568
Akihiro Sunaga, Yuki Matsuoka, Daisaku Nakatani, Katsuki Okada, Hirota Kida, Daisuke Sakamoto, Tetsuhisa Kitamura, Nobuaki Tanaka, Masaharu Masuda, Tetsuya Watanabe, et al. Extensive ablation for persistent atrial fibrillation patients with mitral regurgitation: Insights from the EARNEST-PVI prospective randomized trial. International journal of cardiology. 2024. 132231-132231
Yasuharu Matsunaga-Lee, Koichi Inoue, Nobuaki Tanaka, Masaharu Masuda, Tetsuya Watanabe, Nobuhiko Makino, Yasuyuki Egami, Takafumi Oka, Hitoshi Minamiguchi, Miwa Miyoshi, et al. Appropriate Selection of Substrate Ablation for Persistent Atrial Fibrillation Using Intraprocedural Assessment. Circulation journal : official journal of the Japanese Circulation Society. 2024
Impact of Hospital Scale and Region on Outcomes in Heart Failure with Preserved Ejection Fraction: Insight from the PURSUIT-HFpEF Registry(タイトル和訳中)
(日本循環器学会学術集会抄録集 2023)
The Prognostic Impact of Super-acute Phase Bleeding and Thrombotic Events after Percutaneous Coronary Intervention for Acute Myocardial Infarction(タイトル和訳中)
(日本循環器学会学術集会抄録集 2023)