Rchr
J-GLOBAL ID：201001098777049223
Update date: Feb. 01, 2024
Kimura Keiji
キムラ ケイジ | Kimura Keiji
Affiliation and department：
University of Tsukuba Faculty of Life and Environmental Sciences
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Detailed information
Job title：
Associate Professor
Research field (4)：
Cell biology
, Molecular biology
, Morphology, anatomy
, Genetics
Research keywords (5)：
Mitosis
, SMC protein
, Chromatin structure
, Cell Cycle
, condensin
Research theme for competitive and other funds (9)：
2022 - 2025 RNAと染色体骨格タンパク質群による液-液相分離現象が促すM期染色体制御
2021 - 2022 Regulation of mitotic chromosomes via liquid-liquid phase separation between RNAs and condensin I
2019 - 2022 Analysis of a novel regulatory system of mitosis through nucleolar dynamics
2013 - 2016 Analysis of nucleolar RNA-protein network that regulates mitotic chromosome dynamics
2011 - 2012 核小体因子を介したM期染色体ダイナミクスの制御
2010 - 2012 Regulation of gene expression by chromosome condensation protein, condensin
2010 - 2011 ホスファターゼの新規機能を介した染色体動態制御
2008 - 2009 コンデンシンによる細胞周期特異的なクロマチン構造の制御
2006 - 2007 Analysis of the molecular mechanism and structural basis of the chromosome condensation protein, condensin
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Papers (42)：
Kato, Kazashi, Udagawa, Rina, Hayashi, Yuki, Maki, Masayoshi, Yanagida, Makiko, Higashiura, Sae, Yagishita, Reina, Shimamoto, Haruka, Kimura, Keiji. SF3B14 is involved in the centrosome regulation through splicing of TUBGCP6 pre-mRNA. Biochem Biophys Res Commun. 2022. 588. 133-139
Fujimura, Akiko, Hayashi, Yuki, Kato, Kazashi, Kogure, Yuichiro, Kameyama, Mutsuro, Shimamoto, Haruka, Daitoku, Hiroaki, Fukamizu, Akiyoshi, Hirota, Toru, Kimura, Keiji. Identification of a novel nucleolar protein complex required for mitotic chromosome segregation through centromeric accumulation of Aurora B. Nucleic acids research. 2020. 48. 12. 6583-6596
Lu, Weizhe, Kim, Jun-Dal, Tabara, Saori, Kwon, Chulwon, Mizukami, Hayase, Kimura, Keiji, Fukamizu, Akiyoshi. The N-terminal sequence of murine PRMT5 variant 2 is required for Hsp70 interaction and CHIP ligase-mediated degradation. Biochemical and Biophysical Research Communications. 2019. 514. 4. 1185-1191
Masayoshi Ohkuro, Jun-Dal Kim, Yoshikazu Kuboi, Yuki Hayashi, Hayase Mizukami, Hiroko Kobayashi-Kuramochi, Kenzo Muramoto, Manabu Shirato, Fumiko Michikawa-Tanaka, Jun Moriya, et al. Calreticulin and integrin alpha dissociation induces anti-inflammatory programming in animal models of inflammatory bowel disease. Nature Communications. 2018. 9. 1. 1982
Yuki Hayashi, Akiko Fujimura, Kazashi Kato, Rina Udagawa, Toru Hirota, Keiji Kimura. Nucleolar integrity during interphase supports faithful Cdk1 activation and mitotic entry. Science Advances. 2018. 4. 6. eaap7777
ｍore...
Books (9)：
M期を制御するホスファターゼとその新規機能
細胞工学 2011
染色体凝縮因子コンデンシンの活性を抑制する新たな制御機構
実験医学、羊土社、Vol. 25, No. 4 2007
ヒト培養細胞からのトポイソメラーゼの精製
タンパク質実験マニュアル、朝倉書店 2006
染色体凝縮因子コンデンシンのアフィニティー精製法
タンパク質実験マニュアル、朝倉書店 2006
ヒストンのリン酸化
わかる実験医学シリーズ 注目のエピジェネティクスがわかる 2004
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Lectures and oral presentations (35)：
PP2AとコンデンシンIIの特異的結合の解析
(第40回染色体ワークショップ・第21回核ダイナミクス研究会)
DONSONおよびsororinのpre-mRNAの適切なスプライシングを介した細胞分裂期制御の解明
(第45回日本分子生物学会年会)
SMC5/6複合体の新規サブ複合体の解析
(第45回日本分子生物学会年会)
PP2AとコンデンシンIIの相互作用部位の特定と生理的意義の解明
(第95回日本生化学会大会)
コンデンシンIとRNAによる液-液相分離は分裂期染色体の構造に寄与する
(第39回染色体ワークショップ・第20回核ダイナミクス研究会 2021)
ｍore...
Association Membership(s) (4)：
THE PHARMACEUTICAL SOCIETY OF JAPAN
, The Japanese Cancer Association
, Japan Society for Cell Biology
, The Molecular Biology Society of Japan
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