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J-GLOBAL ID：201002201750806994   Reference number：10A0932091

Oncogenic Ras-mediated downregulation of Clast1/LR8 is involved in Ras-mediated neoplastic transformation and tumorigenesis in NIH3T3 cells

Clast1/LR8の腫瘍性Ras介在性下方調節はNIH3T3細胞におけるRas介在性悪性形質転換と腫瘍形成に関与する

Author (10)： RYU Sun-Hyo (Chosun Univ. School of Medicine, Gwangju) ,  KIM Ki Hwan (Seoul National Univ., Seoul) ,  KIM Hong-Beum (Chosun Univ. School of Medicine, Gwangju) ,  KIM Mi-Hwa (Chosun Univ. School of Medicine, Gwangju) ,  KIM Na-Hee (Chosun Univ. School of Medicine, Gwangju) ,  KANG Yoonsung (Chosun Univ. School of Medicine, Gwangju) ,  HYUN Jin Won (Cheju National Univ., Jeju) ,  SEO Hong Joo (Dep. of Thoracic and Cardiovascular Surgery, Gwangju) ,  JUN Jae-Yeul (Chosun Univ. School of Medicine, Gwangju, KOR) ,  YOU Ho Jin (Chosun Univ. School of Medicine, Gwangju)
Material： Cancer Science  (Cancer Sci)
Volume： 101  Issue： 9  Page： 1990-1996  Publication year： Sep. 2010 
JST Material Number： W1423A  ISSN： 1347-9032  Document type： Article
Article type： 原著論文  Country of issue： Australia (AUS)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *tumorigenesis ,...

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JST classification (1)： Carcinogenic mechanisms and factors  (GE02020C)

Reference (33)：

• LOWY, DR. Function and regulation of ras. Annu Rev Biochem. 1993, 62, 851-891
• CAMPBELL, SL. Increasing complexity of Ras signaling. Oncogene. 1998, 17, 1395-1413
• WHITE, MA. Multiple Ras functions can contribute to mammalian cell transformation. Cell. 1995, 80, 533-541
• SCHUBBERT, S. Hyperactive Ras in developmental disorders and cancer. Nat Rev Cancer. 2007, 7, 295-308
• BARDEESY, N. Pancreatic cancer biology and genetics. Nat Rev Cancer. 2002, 2, 897-909

Terms in the title (5)： 腫瘍性 ,  下方調節 ,  NIH3T3細胞 ,  悪性形質転換 ,  腫瘍形成