Art

J-GLOBAL ID：201002209250763050   Reference number：10A0454845

Structural requirements of penetratin absorption enhancement efficiency for insulin delivery

インシュリンデリバリーに対するペネトラチン吸収増強効率の構造条件

Author (6)： KHAFAGY El-sayed (Dep. of Pharmaceutics, Hoshi Univ., Ebara 2-4-41, Shinagawa, Tokyo 142-8501, JPN) ,  MORISHITA Mariko (Dep. of Pharmaceutics, Hoshi Univ., Ebara 2-4-41, Shinagawa, Tokyo 142-8501, JPN) ,  IDA Nobuo (New Frontiers Res. Labs., Toray Industries, Inc., Tebiro 6-10-1, Kamakura, Kanagawa 248-8555, JPN) ,  NISHIO Reiji (New Frontiers Res. Labs., Toray Industries, Inc., Tebiro 6-10-1, Kamakura, Kanagawa 248-8555, JPN) ,  ISOWA Koichi (The Center of Japan Biological Chemistry Co. Ltd., Fukue 52, Kaizu-gun, Gifu 503-0628, JPN) ,  TAKAYAMA Kozo (Dep. of Pharmaceutics, Hoshi Univ., Ebara 2-4-41, Shinagawa, Tokyo 142-8501, JPN)
Material： Journal of Controlled Release  (J Control Release)
Volume： 143  Issue： 3  Page： 302-310  Publication year： May. 10, 2010 
JST Material Number： C0308D  ISSN： 0168-3659  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： peptide ,...
Semi thesaurus term： cell physiology ,...

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JST classification (4)： Pharmaceutical preparations in general  (GY02010Z) ,  Basic biopharmacy  (GY01021U) ,  Basic research of drugs acting on carbohydrate metabolism  (GW13020Q) ,  Bioactive peptides  (EB08100U)

Substance index (1)： Penetratin

Reference (41)：

• C. Foged, H.M. Nielsen, Cell-penetrating peptides for drug delivery across membrane barriers, Expert Opin. Drug Deliv. 5 (2008) 105-117.
• L.N. Patel, J.L. Zaro, W.C. Shen, Cell penetrating peptides: intracellular pathways and pharmaceutical perspectives, Pharm. Res. 24 (2007) 1977-1992.
• S. Pujals, J. Fernández-Carneado, C. López-Iglesias, M.J. Kogan, E. Giralt, Mechanistic aspects of CPP-mediated intracellular drug delivery: relevance of CPP self-assembly, Biochim. Biophys. Acta 1758 (2006) 264-279.
• R. Tréhin, H.P. Merkle, Chances and pitfalls of cell penetrating peptides for cellular drug delivery, Eur. J. Pharm. Biopharm. 58 (2004) 209-223.
• K.M. Wagstaff, D.A. Jans, Protein transduction: cell penetrating peptides and their therapeutic applications, Curr. Med. Chem. 13 (2006) 1371-1387.

Terms in the title (4)： インシュリン ,  デリバリー ,  ペネトラチン ,  増強