Art

J-GLOBAL ID：201002220105105544   Reference number：10A0471626

C₂-ceramide inhibits the prostaglandin E₂-induced accumulation of cAMP in human gingival fibroblasts

C₂-セラミドは,ヒト歯肉線維芽細胞におけるcAMPのプロスタグランジンE₂誘発蓄積を阻害する

Author (5)： NAKAO Sumi (Dep. of Oral Molecular Pharmacology, Nihon Univ. School of Dentistry at Matsudo) ,  MORIYAMA Seiko (Dep. of Physiology, Nihon Univ. School of Dentistry at Matsudo) ,  SEGAWA Masaomi (Dep. of Physiology, Nihon Univ. School of Dentistry at Matsudo) ,  GUO Ming-yu (Dep. of Physiology, Nihon Univ. School of Dentistry at Matsudo) ,  SUGIYA Hiroshi (Dep. of Physiology, Nihon Univ. School of Dentistry at Matsudo)
Material： Biomedical Research  (Biomed Res)
Volume： 31  Issue： 2  Page： 97-103 (J-STAGE)  Publication year： 2010 
JST Material Number： Z0236B  ISSN： 0388-6107  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： fibroblast ,...
Semi thesaurus term： agonist

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JST classification (2)： Biological function  (EB05020M) ,  Mouth(=oral cavity),esophagus  (EJ06020R)

Substance index (3)： cAMP ,  N-Acetylsphingosine ,  Dinoprostone

Reference (37)：

• 1. Arai H, Nomura Y, Kinoshita M, Nishimura F, Takigawa M, Takahashi K, Washio N, Takashiba S and Murayama Y (1998) The inhibition of DNA synthesis by prostaglandin E₂ in human gingival fibroblasts is independent of the cyclic AMP-protein kinase A signal transduction pathway. J Periodontal Res 33, 33-39.
• 2. Barrantes FJ (2007) Cholesterol effects on nicotinic acetylcholine receptor. J Neurochem 103, 72-80.
• 3. Bastien L, Sawyer N, Grygorczyk R, Met ters KM and Adam M (1994) Cloning, functional expression, and characterization of the human prostaglandin E2 receptor EP2 subtype. J Biol Chem 269, 11873-11877.
• 4. Björkqvist YJ, Nyholm TK, Slotte JP and Ramstedt B (2005) Domain formation and stability in complex lipid bilayers as reported by cholestatrienol. Biophys J 88, 4054-4063.
• 5. Borroni V, Baier CJ, Lang T, Bonini I, White MM, Garbus I and Barrantes FJ (2007) Cholesterol depletion activates rapid internalization of submicron-sized acetylcholine receptor domains at the cell membrane. Mol Membr Biol 24, 1-15.

Terms in the title (8)： C2-セラミド ,  ヒト ,  歯肉線維芽細胞 ,  cAMP ,  プロスタグランジンE2 ,  誘発 ,  蓄積 ,  阻害