Art

J-GLOBAL ID：201002220912169718   Reference number：10A0854469

PD-1 deficiency results in the development of fatal myocarditis in MRL mice

MRLマウスではPD-1が欠損すると致死性心筋炎が発症する

Author (11)： WANG Jian (Kyoto Univ., Kyoto, JPN) ,  OKAZAKI Il-mi (Kyoto Univ., Kyoto, JPN) ,  OKAZAKI Il-mi (Univ. Tokushima, Tokushima, JPN) ,  YOSHIDA Taku (Kyoto Univ., Kyoto, JPN) ,  CHIKUMA Shunsuke (Kyoto Univ., Kyoto, JPN) ,  KATO Yu (Kyoto Univ., Kyoto, JPN) ,  NAKAKI Fumio (Kyoto Univ., Kyoto, JPN) ,  HIAI Hiroshi (Shiga Medical Center Res. Inst., Shiga, JPN) ,  HONJO Tasuku (Kyoto Univ., Kyoto, JPN) ,  OKAZAKI Taku (Kyoto Univ., Kyoto, JPN) ,  OKAZAKI Taku (Univ. Tokushima, Tokushima, JPN)
Material： International Immunology  (Int Immunol)
Volume： 22  Issue： 6  Page： 443-452  Publication year： Jun. 2010 
JST Material Number： W0116A  ISSN： 0953-8178  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *protein ,...
Semi thesaurus term： T lymphocyte ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=10A0854469&from=J-GLOBAL&jstjournalNo=W0116A") }}

JST classification (2)： Immunologic diseases,allergic diseases in general.  (GD04010C) ,  Cardiovascular system diseases  (GJ03000C)

Reference (39)：

• Okazaki, T. and Honjo, T. 2006. The PD-1-PD-L pathway in immunological tolerance. Trends Immunol. 27:195.
• Greenwald, R. J., Freeman, G. J. and Sharpe, A. H. 2005. The B7 family revisited. Annu. Rev. Immunol. 23:515.
• Day, C. L., Kaufmann, D. E., Kiepiela, P. et al. 2006. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443:350.
• Trautmann, L., Janbazian, L., Chomont, N. et al. 2006. Upregulation of PD-1 expression on HIV-specific CD8 + T cells leads to reversible immune dysfunction. Nat. Med. 12:1198.
• Thompson, R. H., Gillett, M. D., Cheville, J. C. et al. 2004. Costimulatory B7-H1 in renal cell carcinoma patients: indicator of tumor aggressiveness and potential therapeutic target. Proc. Nati Acad. Sci. USA 101:17174.

Terms in the title (6)： マウス ,  PD-1 ,  欠損 ,  致死性 ,  心筋炎 ,  発症