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J-GLOBAL ID：201002220974662895   Reference number：10A1376553

MicroRNAs and Their Therapeutic Potential for Human Diseases: Aberrant MicroRNA Expression in Alzheimer’s Disease Brains

マイクロRNAs及びヒト疾患に対するその治療可能性:Alzheimer病脳における異常マイクロRNA発現

Author (1)： SATOH Jun-ichi (Dep. of Bioinformatics and Molecular Neuropathology, Meiji Pharmaceutical Univ., JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 114  Issue： 3  Page： 269-275 (J-STAGE)  Publication year： 2010 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Alzheimer Disease ,...
Semi thesaurus term： miRNA

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JST classification (2)： Nervous system diseases  (GN03000O) ,  Molecular genetics in general  (EC02010J)

Reference (28)：

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• 2 Selbach M, Schwanhäusser B, Thierfelder N, Fang Z, Khanin R, Rajewsky N. Widespread changes in protein synthesis induced by microRNAs. Nature. 2008;455:58–63.
• 3 Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet. 2008;9:102–114.
• 4 Vasudevan S, Tong Y, Steitz JA. Switching from repression to activation: microRNAs can up-regulate translation. Science. 2007;318:1931–1934.
• 5 Place RF, Li LC, Pookot D, Noonan EJ, Dahiya R. MicroRNA-373 induces expression of genes with complementary promoter sequences. Proc Natl Acad Sci U S A. 2008;105:1608–1613.

Terms in the title (7)： ヒト疾患 ,  治療 ,  可能性 ,  Alzheimer病 ,  脳 ,  マイクロRNA ,  発現