Art

J-GLOBAL ID：201002226532683190   Reference number：10A0243654

Upregulation of Monocyte Tissue Factor Activity Is Significantly Associated With Low-Grade Chronic Inflammation and Insulin Resistance in Patients With Metabolic Syndrome

単球組織因子活性のアップレギュレーションはメタボリックシンドローム患者の軽度慢性炎症及びインシュリン抵抗性と顕著に関連する

Author (8)： NAKAGOMI Akihiro (Dep. of Internal Medicine and Cardiology, Tama-Nagayama Hospital, Nippon Medical School) ,  SASAKI Mihoko (Dep. of Pharmaceutical, Tokyo Univ. of Pharmacy and Life Sci.) ,  ISHIKAWA Youhei (Dep. of Pharmaceutical, Tokyo Univ. of Pharmacy and Life Sci.) ,  MORIKAWA Masako (Dep. of Pharmaceutical, Tokyo Univ. of Pharmacy and Life Sci.) ,  SHIBUI Toshiyuki (Dep. of Internal Medicine and Cardiology, Tama-Nagayama Hospital, Nippon Medical School) ,  KUSAMA Yoshiki (Dep. of Internal Medicine and Cardiology, Tama-Nagayama Hospital, Nippon Medical School) ,  ATARASHI Hirotsugu (Dep. of Internal Medicine and Cardiology, Tama-Nagayama Hospital, Nippon Medical School) ,  MIZUNO Kyoichi (Div. of Cardiology, Hepatology, Geriatrics, and Integrated Medicine, Dep. of Internal Medicine, Nippon Medical School)
Material： Circulation Journal  (Circ J)
Volume： 74  Issue： 3  Page： 572-577 (J-STAGE)  Publication year： 2010 
JST Material Number： F0908A  ISSN： 1346-9843  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： monocyte ,...
Semi thesaurus term： *insulin resistance ,...

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JST classification (3)： Biological function  (EB03040U) ,  Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Cardiovascular system diseases  (GJ03000C)

Reference (27)：

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• TAKENO, M. Impact of metabolic syndrome on the long-term survival of patients with acute myocardial infarction : Potential association with C-reactive protein. Circ J. 2008, 72, 415-419
• MATSUO, Y. Metabolic syndrome is strongly associated with chronic subclinical inflammation in patients achieving optimal low-density lipoprotein-cholesterol levels in secondary prevention of cardiovascular disease. Circ J. 2008, 72, 2046-2050
• GUSTAFSON, B. Inflamed adipose tissue : A culprit underlying the metabolic syndrome and atherosclerosis. Arterioscler Thromb Vasc Biol. 2007, 27, 2276-2283
• DIAMANT, M. Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus. Circulation. 2002, 106, 2442-2447

Terms in the title (9)： 単球 ,  組織因子 ,  活性 ,  アップレギュレーション ,  メタボリックシンドローム ,  患者 ,  軽度 ,  慢性炎症 ,  インシュリン抵抗性