Art

J-GLOBAL ID：201002229851134816   Reference number：10A0216663

Dopamine facilitates α-synuclein oligomerization in human neuroblastoma SH-SY5Y cells

ドーパミンはヒト神経芽腫SH-SY5Y細胞におけるα-シヌクレインのオリゴマー化を促進する

Author (10)： YAMAKAWA Kentaro (Clinical Res. Center, Utano National Hospital, National Hospital Organization, Kyoto 616-8255, JPN) ,  IZUMI Yasuhiko (Dep. of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto Univ., Kyoto, JPN) ,  TAKEUCHI Hiroki (Dep. of Neurology, Graduate School of Medicine, Kyoto Univ., Kyoto, JPN) ,  YAMAMOTO Noriyuki (Dep. of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto Univ., Kyoto, JPN) ,  KUME Toshiaki (Dep. of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto Univ., Kyoto, JPN) ,  AKAIKE Akinori (Dep. of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto Univ., Kyoto, JPN) ,  TAKAHASHI Ryosuke (Dep. of Neurology, Graduate School of Medicine, Kyoto Univ., Kyoto, JPN) ,  SHIMOHAMA Shun (Dep. of Neurology, Graduate School of Medicine, Kyoto Univ., Kyoto, JPN) ,  SHIMOHAMA Shun (Dep. of Neurology, School of Medicine, Sapporo Medical Univ., Hokkaido, JPN) ,  SAWADA Hideyuki (Clinical Res. Center, Utano National Hospital, National Hospital Organization, Kyoto 616-8255, JPN)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 391  Issue： 1  Page： 129-134  Publication year： Jan. 01, 2010 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： cultured cell ,  *protein ,  *oligomerization ,  Parkinson's disease ,  molecular sieve ,  neuron ,  cytotoxicity ,  Lewy body ,  substantia nigra ,  catecholamine ,  primary amine
Semi thesaurus term： SH-SY5Y cell ,  *alpha-Synuclein ,  Dopaminergic neuron

JST classification (1)： Function of cell components  (EF03060C)

Substance index (1)： Dopamine

Terms in the title (7)： ドーパミン ,  ヒト ,  神経芽腫 ,  SH-SY5Y細胞 ,  α-シヌクレイン ,  オリゴマー化 ,  促進