Art

J-GLOBAL ID：201002236581860435   Reference number：10A0213472

Inactivation of Peroxiredoxin I by Phosphorylation Allows Localized H₂O₂ Accumulation for Cell Signaling

リン酸化によるペルオキシレドキシンIの不活性化は細胞シグナリングの局在型H₂O₂蓄積を可能にする

Author (6)： WOO Hyun Ae (Div. of Life and Pharmaceutical Sciences, Ewha Womans Univ., Seoul 120-750, KOR) ,  YIM Sun Hee (Div. of Life and Pharmaceutical Sciences, Ewha Womans Univ., Seoul 120-750, KOR) ,  SHIN Dong Hae (Div. of Life and Pharmaceutical Sciences, Ewha Womans Univ., Seoul 120-750, KOR) ,  KANG Dongmin (Div. of Life and Pharmaceutical Sciences, Ewha Womans Univ., Seoul 120-750, KOR) ,  YU Dae-yeul (Aging Res. Center, Korea Res. Inst. of Bioscience and Biotechnology, Daejeon 305-333, KOR) ,  RHEE Sue Goo (Div. of Life and Pharmaceutical Sciences, Ewha Womans Univ., Seoul 120-750, KOR)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 140  Issue： 4  Page： 517-528  Publication year： Feb. 19, 2010 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： Proteins ,  phosphorylation ,  *enzyme inhibition ,  *Hydrogen Peroxide ,  amino acid residue ,  Wound Healing ,  subcellular distribution ,  cytotoxicity ,  enzyme activity ,  EGF ,  PDGF ,  knockout mouse ,  enzyme inhibitor ,  tumor cell ,  cultured cell ,  injury ,  skin disease ,  peroxidation ,  post-translational modification ,  coenzyme ,  adenine nucleotide ,  nicotinamide mononucleotide ,  A431 cell ,  cysteine residue ,  tyrosine phosphorylation ,  tyrosine residue ,  Protein Kinase Inhibitors ,  Skin injury ,  *peroxiredoxin 1 ,  *Oxidoreductases ,  Signal Transduction ,  *enzyme deactivation ,  laboratory animal ,  Mus musculus ,  damage and injury
Semi thesaurus term： *oxidoreductase ,  cellular signal transduction ,  *enzyme inactivation

JST classification (2)： Cell physiology in general  (EF02010S) ,  Enzyme in general  (EB09010D)

Substance index (3)： AG-1478 ,  NADPH ,  PP1

Terms in the title (6)： リン酸化 ,  ペルオキシレドキシンI ,  不活性化 ,  細胞シグナリング ,  H2O2 ,  蓄積