Art

J-GLOBAL ID：201002246630507709   Reference number：10A0504863

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

TIMP3の近くの遺伝的バリアントと高密度リタンパク質関連遺伝子座は加齢黄斑変性症に対する感受性に影響する

Author (40)： CHEN Wei (Univ. Michigan, MI) ,  STAMBOLIAN Dwight (Univ. Pennsylvania, PA) ,  EDWARDS Albert O. (Mayo Clinic, MN) ,  BRANHAM Kari E. (Univ. Michigan, MI) ,  OTHMAN Mohammad (Univ. Michigan, MI) ,  JAKOBSDOTTIR Johanna (Univ. Pittsburgh, PA) ,  TOSAKULWONG Nirubol (Mayo Clinic, MN) ,  PERICAK-VANCE Margaret A. (Univ. Miami Miller School of Medicine, FL) ,  CAMPOCHIARO Peter A. (Johns Hopkins Univ. School of Medicine, MD) ,  KLEIN Michael L. (Oregon Health and Sci. Univ., OR) ,  TAN Perciliz L. (Johns Hopkins Univ. School of Medicine, MD) ,  CONLEY Yvette P. (Univ. Pittsburgh, PA) ,  KANDA Atsuhiro (National Eye Inst., MD) ,  KOPPLIN Laura (Case Western Reserve Univ., OH) ,  LI Yanming (Univ. Michigan, MI) ,  AUGUSTAITIS Katherine J. (Univ. Michigan, MI) ,  KAROUKIS Athanasios J. (Univ. Michigan, MI) ,  SCOTT William K. (Univ. Miami Miller School of Medicine, FL) ,  AGARWAL Anita (Vanderbilt Univ. Medical Center, TN) ,  KOVACH Jaclyn L. (Univ. Miami Miller School of Medicine, FL) ,  SCHWARTZ Stephen G. (Univ. Miami Miller School of Medicine, FL) ,  POSTEL Eric A. (Duke Univ. Medical Center, NC) ,  BROOKS Matthew (National Eye Inst., MD) ,  BARATZ Keith H. (Mayo Clinic, MN) ,  BROWN William L. (Mayo Clinic, MN) ,  BRUCKER Alexander J. (Univ. Pennsylvania, PA) ,  ORLIN Anton (Univ. Pennsylvania, PA) ,  BROWN Gary (Mid-Atlantic Retina, NJ) ,  BROWN Gary (Thomas Jefferson Univ., PA) ,  HO Allen (Mid-Atlantic Retina, NJ) ,  HO Allen (Thomas Jefferson Univ., PA) ,  REGILLO Carl (Mid-Atlantic Retina, NJ) ,  REGILLO Carl (Thomas Jefferson Univ., PA) ,  DONOSO Larry (Philadelphia Retina Endowment Fund, PA) ,  TIAN Lifeng (Univ. Pennsylvania, PA) ,  KADERLI Brian (Univ. Pennsylvania, PA) ,  HADLEY Dexter (Univ. Pennsylvania, PA) ,  HAGSTROM Stephanie A. (Case Western Reserve Univ., OH) ,  HAGSTROM Stephanie A. (Cleveland Clinical Foundation, OH) ,  PEACHEY Neal S. (Case Western Reserve Univ., OH)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 107  Issue： 16  Page： 7401-7406  Publication year： Apr. 20, 2010 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： *retinal degeneration ,  *senile change ,  proteinase inhibitor ,  HDL ,  gene locus ,  *statistical analysis ,  extracellular matrix ,  lipid metabolism ,  sterol ,  allele ,  single nucleotide polymorphism ,  HDL cholesterol
Semi thesaurus term： *age related macular degeneration ,  TIMP-3 ,  *association analysis

JST classification (2)： Metabolism in general  (EB05030X) ,  Eye diseases  (GP03000U)

Terms in the title (7)： TIMP3 ,  遺伝的バリアント ,  高密度 ,  タンパク質 ,  遺伝子座 ,  加齢黄斑変性症 ,  感受性