Art

J-GLOBAL ID：201002251226874394   Reference number：10A0108485

Mesenchymal stem cells cultured under hypoxia escape from senescence via down-regulation of p16 and extracellular signal regulated kinase

p16と細胞外シグナル調節キナーゼのダウンレギュレーションを介した老化からの低酸素エスケープ下で培養した間葉幹細胞

Author (16)： JIN Yonghui (Dep. of Tissue Regeneration, Inst. for Frontier Medical Sciences, Kyoto Univ., JPN) ,  KATO Tomohisa (Dep. of Tissue Regeneration, Inst. for Frontier Medical Sciences, Kyoto Univ., JPN) ,  FURU Moritoshi (Dep. of Tissue Regeneration, Inst. for Frontier Medical Sciences, Kyoto Univ., JPN) ,  NASU Akira (Dep. of Tissue Regeneration, Inst. for Frontier Medical Sciences, Kyoto Univ., JPN) ,  NASU Akira (Dep. of Orthopaedic Surgery, Graduate School of Medicine, Kyoto Univ., JPN) ,  KAJITA Yoichiro (Dep. of Tissue Regeneration, Inst. for Frontier Medical Sciences, Kyoto Univ., JPN) ,  KAJITA Yoichiro (Dep. of Urology, Graduate School of Medicine, Kyoto Univ., JPN) ,  MITSUI Hiroto (Dep. of Tissue Regeneration, Inst. for Frontier Medical Sciences, Kyoto Univ., JPN) ,  MITSUI Hiroto (Dep. of Musculoskeletal Medicine, Graduate School of Medical Sciences, Nagoya City Univ., JPN) ,  UEDA Michiko (Dep. of Tissue Regeneration, Inst. for Frontier Medical Sciences, Kyoto Univ., JPN) ,  AOYAMA Tomoki (Human Health Sciences, Graduate School of Medicine, Kyoto Univ., JPN) ,  NAKAYAMA Tomitaka (Dep. of Orthopaedic Surgery, Graduate School of Medicine, Kyoto Univ., JPN) ,  NAKAMURA Takashi (Dep. of Orthopaedic Surgery, Graduate School of Medicine, Kyoto Univ., JPN) ,  TOGUCHIDA Junya (Dep. of Tissue Regeneration, Inst. for Frontier Medical Sciences, Kyoto Univ., JPN) ,  TOGUCHIDA Junya (Dep. of Orthopaedic Surgery, Graduate School of Medicine, Kyoto Univ., JPN) ,  TOGUCHIDA Junya (Center for iPS Cell Res. and Application, Inst. for Integrated Cell - Material Sciences, Kyoto Univ., JPN)
Material： Biochemical and Biophysical Research Communications  (BBRC)
Volume： 391  Issue： 3  Page： 1471-1476  Publication year： Jan. 15, 2010 
JST Material Number： B0118A  ISSN： 0006-291X  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： enzyme inhibitor ,  Proteins ,  ERK ,  *senile change ,  *oxygen deficiency ,  *mesenchymal cell ,  fat cell ,  Cell Differentiation ,  osteogenesis ,  MAP kinase ,  Cyclin-Dependent Kinase Inhibitor p16 ,  differentiation (biology) ,  developmental physiology
Semi thesaurus term： p16 protein

JST classification (1)： Cell components in general  (EF03010Z)

Terms in the title (7)： p16 ,  細胞外シグナル調節キナーゼ ,  ダウンレギュレーション ,  老化 ,  低酸素 ,  培養 ,  間葉幹細胞