Art

J-GLOBAL ID：201002252359831791   Reference number：10A0994531

Advanced Research on Dopamine Signaling to Develop Drugs for the Treatment of Mental Disorders: Regulation of Dopaminergic Neural Transmission by Tyrosine Hydroxylase Protein at Nerve Terminals

精神疾患治療薬開発のためのドーパミンシグナルに関する先端研究:神経終末においてチロシン水酸化酵素蛋白によるドーパミン作動性神経伝達の制御

Author (5)： SUMI-ICHINOSE Chiho (Dep. of Pharmacology, School of Medicine, Fujita Health Univ., JPN) ,  ICHINOSE Hiroshi (Dep. of Life Sci., Graduate School of Bioscience and Biotechnology, Tokyo Inst. of Technol., JPN) ,  IKEMOTO Kazuhisa (Dep. of Pharmacology, School of Medicine, Fujita Health Univ., JPN) ,  NOMURA Takahide (Dep. of Pharmacology, School of Medicine, Fujita Health Univ., JPN) ,  KONDO Kazunao (Dep. of Pharmacology, School of Medicine, Fujita Health Univ., JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 114  Issue： 1  Page： 17-24 (J-STAGE)  Publication year： 2010 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： nerve ending ,...
Semi thesaurus term： GTP Cyclohydrolase ,...

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JST classification (2)： Basic neurology  (GN01020W) ,  Gene manipulation  (EC02050B)

Substance index (2)： Tetrahydrobiopterin ,  6-Pyruvoyltetrahydropterin

Reference (38)：

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• KWON, NS. Reduced biopterin as a cofactor in the generation of nitrogen oxides by marine macrophages. J Biol Chem. 1989, 264, 20496-20501
• GARTHWAITE, J. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain. Nature. 1988, 336, 385-388
• BOGDAN, C. Nitric oxide and the immune response. Nat Immunol. 2001, 2, 907-916
• FORSTERMANN, U. Endothelial nitric oxide synthase in vascular disease : from marvel to menace. Circulation. 2006, 113, 1708-1714

Terms in the title (8)： 精神疾患 ,  治療薬開発 ,  研究 ,  神経終末 ,  チロシン水酸化酵素 ,  蛋白 ,  ドーパミン ,  神経伝達