Art

J-GLOBAL ID：201002254753057794   Reference number：10A0060446

Immunohistochemical Detection of 13(R)-hydroxyoctadecadienoic Acid in Atherosclerotic Plaques of Human Carotid Arteries Using a Novel Specific Antibody

新規特異抗体を用いたヒト頸動脈のアテローム性動脈硬化性プラークにおける13(R)-ヒドロキシオクタデカジエン酸の免疫組織化学的検出

Author (10)： SHIBATA Noriyuki (Dep. of Pathology, Tokyo Women’s Medical Univ.) ,  TOI Sono (Dep. of Neurology, Tokyo Women’s Medical Univ.) ,  SHIBATA Takahiro (Lab. of Food and Biodynamics, Nagoya Univ. Graduate School of Bioagricultural Sciences) ,  UCHIDA Koji (Lab. of Food and Biodynamics, Nagoya Univ. Graduate School of Bioagricultural Sciences) ,  ITABE Hiroyuki (Dep. of Biological Chemistry, Showa Univ. School of Pharmaceutical Sciences) ,  SAWADA Tatsuo (Dep. of Pathology, Tokyo Women’s Medical Univ.) ,  KAWAMATA Takakazu (Dep. of Neurosurgery, Yachiyo Medical Center) ,  OKADA Yoshikazu (Dep. of Neurosurgery, Tokyo Women’s Medical Univ.) ,  UCHIYAMA Shinichiro (Dep. of Neurology, Tokyo Women’s Medical Univ.) ,  KOBAYASHI Makio (Dep. of Pathology, Tokyo Women’s Medical Univ.)
Material： Acta Histochemica et Cytochemica  (Acta Histochem Cytochem)
Volume： 42  Issue： 6  Page： 197-203 (J-STAGE)  Publication year： 2009 
JST Material Number： Z0149B  ISSN： 0044-5991  CODEN： ACHCBO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *Carotid artery atheroma ,...

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JST classification (3)： Clinical medicine on cardiovascular system in general  (GJ01030V) ,  Vasculature  (EJ04030O) ,  Production and application of antigens,antibodies,complements  (ED04030W)

Substance index (1)： (R)-13-Hydroxyoctadeca-9,11-dienoic acid

Reference (25)：

• 1. Baer, A. N., Costello, P. B. and Green, F. A. (1991) Stereospecificity of the hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids produced by cultured bovine endothelial cells. Biochim. Biophys. Acta 1085; 45-52.
• 2. Birukov, K. G. (2006) Oxidized lipids: the two faces of vascular inflammation. Curr. Atheroscler. Rep. 8; 223-231.
• 3. Buchanan, M. R., Haas, T. A., Lagarde, M. and Guichardant, M. (1985) 13-Hydroxyoctadecadienoic acid is the vessel wall chemorepellant factor, LOX. J. Biol. Chem. 260; 16056-16059.
• 4. Buchanan, M. R., Bertomeu, M. C., Haas, T. A., Orr, W. and Eltringham-Smith, L. L. (1993) Localization of 13-hydroxyoctadecadienoic acid and the vitronectin receptor in human endothelial cells and endothelial cell/platelet interactions in vitro. Blood 81; 3303-3312.
• 5. Fearon, I. M. and Faux, S. P. (2009) Oxidative stress and cardiovascular disease: novel tools give (free) radical insight. J. Mol. Cell. Cardiol. 47; 372-381.

Terms in the title (7)： 特異抗体 ,  ヒト ,  頸動脈 ,  アテローム性動脈硬化 ,  プラーク ,  酸 ,  免疫組織化学