Art

J-GLOBAL ID：201002256676527114   Reference number：10A0445253

Local Administration of a Synthetic Cell-Penetrating Peptide Antagonizing TrkA Function Suppresses Inflammatory Pain in Rats

TrkA拮抗合成細胞膜貫通ペプチドの局所投与は,ラットにおいて炎症性疼痛を抑制する

Author (7)： UEDA Koyo (Dep. of Anesthesiology and Reanimatology, Fac. of Medical Sciences, Univ. of Fukui, JPN) ,  HIROSE Munetaka (Dep. of Anesthesiology and Reanimatology, Fac. of Medical Sciences, Univ. of Fukui, JPN) ,  MURATA Eri (Dep. of Anesthesiology and Reanimatology, Fac. of Medical Sciences, Univ. of Fukui, JPN) ,  TAKATORI Mayumi (Dep. of Anesthesiology, Kyoto Prefectural Univ. of Medicine, JPN) ,  UEDA Masashi (Dep. of Anesthesiology and Reanimatology, Fac. of Medical Sciences, Univ. of Fukui, JPN) ,  IKEDA Hiroshi (Dep. of Human and Artificial Intelligence Systems, Graduate School of Engineering, Univ. of Fukui, JPN) ,  SHIGEMI Kenji (Dep. of Anesthesiology and Reanimatology, Fac. of Medical Sciences, Univ. of Fukui, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 112  Issue： 4  Page： 438-443 (J-STAGE)  Publication year： 2010 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *receptor tyrosine kinase ,...
Semi thesaurus term： *NGF receptor ,...

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JST classification (1)： Basic research of antipyretic analgesics  (GW03040H)

Reference (26)：

• HEFTI, FF. Novel class of pain drugs based on antagonism of NGF. Trends Pharmacol Sci. 2006, 27, 85-91
• XIAN, CJ. Treating skeletal pain : limitations of conventional anti-inflammatory drugs, and anti-neurotrophic factor as a possible alternative. Nat Clin Pract Rheumatol. 2009, 5, 92-98
• UEDA, M. Nerve growth factor induces systemic hyperalgesia after thoracic burn injury in the rat. Neurosci Lett. 2002, 328, 97-100
• SUMMER, GJ. TrkA and PKC-epsilon in thermal burn-induced mechanical hyperalgesia in the rat. J Pain. 2006, 7, 884-891
• WU, C. Nerve growth factor expression after plantar incision in the rat. Anesthesiology. 2007, 107, 128-135

Terms in the title (6)： TrkA ,  拮抗 ,  細胞膜貫通ペプチド ,  局所投与 ,  ラット ,  炎症性疼痛