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J-GLOBAL ID：201002279725261494   Reference number：10A0088429

Decreased Subepithelial Microvasculature Observed by High Magnification Bronchovideoscope in the Large Airways of Smokers

高倍率気管支ビデオ内視鏡により喫煙者の太い気道に確認された減少した上皮下微小血管系

Author (7)： YAMADA Gen (The Third Dep. of Internal Medicine, Sapporo Medical Univ. School of Medicine) ,  SHIJUBO Noriharu (Dep. of Respiratory Medicine, Sapporo Hospital of Hokkaido Railway Co.) ,  KITADA Junya (The Third Dep. of Internal Medicine, Sapporo Medical Univ. School of Medicine) ,  TAKAHASHI Mamoru (The Third Dep. of Internal Medicine, Sapporo Medical Univ. School of Medicine) ,  OTSUKA Mitsuo (The Third Dep. of Internal Medicine, Sapporo Medical Univ. School of Medicine) ,  FUJII Masaru (The Third Dep. of Internal Medicine, Sapporo Medical Univ. School of Medicine) ,  TAKAHASHI Hiroki (The Third Dep. of Internal Medicine, Sapporo Medical Univ. School of Medicine)
Material： Internal Medicine (Web)  (Intern Med (Web))
Volume： 47  Issue： 18  Page： 1579-1583 (J-STAGE)  Publication year： 2008 
JST Material Number： U0033A  ISSN： 1349-7235  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： *smoker ,...

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JST classification (3)： Tobacco(=cigarette)  (FJ07000D) ,  Clinical medicine on respiratory system in general  (GI01030S) ,  Clinical medicine on cardiovascular system in general  (GJ01030V)

Reference (15)：

• 1. Koyama S, Sato E, Haniuda M, Numanami H, Nagai S, Izumi T. Decreased level of vascular endothelial growth factor in bronchoalveolar lavage fluid of normal smokers and patients with pulmonary fibrosis. Am J Respir Crit Care Med 166: 382-385, 2002.
• 2. Nagai K, Betsuyaku T, Itoh Y, Nasuhara Y, Nishimura M. Decrease of vascular endothelial growth factor in macrophages from long-term smokers. Eur Respir J 25: 626-633, 2005.
• 3. Su Y, Cao W, Han Z, Block ER. Cigarette smoke extract inhibits angiogenesis of pulmonary artery endothelial cells: the role of calpain. Am J Physiol Lung Cell Mol Physiol 287: L794-L800, 2007.
• 4. Kondo T, Hayashi M, Takeshita K, et al. Smoking cessation rapidly increases circulating progenitor cells in peripheral blood in chronic smokers. Arterioscler Thromb Vasc Bior 24: 1442-1427, 2004.
• 5. Hiroshima K, Iyoda A, Shibuya K, et al. Evidence of neoanginogenesis and an increase in the number of proliferating cells within the bronchial epithelium of smokers. Cancer 95: 1539-1545, 2002.

Terms in the title (7)： 高倍率 ,  気管支 ,  ビデオ内視鏡 ,  喫煙者 ,  気道 ,  上皮 ,  微小血管系