Art

J-GLOBAL ID：201002279816597746   Reference number：10A0216980

In-vivo visualization of key molecular processes involved in Alzheimer’s disease pathogenesis: Insights from neuroimaging research in humans and rodent models

Alzheimer病病理に関係する主要な分子過程のIn-vivo可視化:ヒトおよび齧歯類モデルでの神経画像研究からの見識

Author (8)： HIGUCHI Makoto (Molecular Imaging Center, National Inst. of Radiological Sciences, Chiba 263-8555, JPN) ,  MAEDA Jun (Molecular Imaging Center, National Inst. of Radiological Sciences, Chiba 263-8555, JPN) ,  JI Bin (Molecular Imaging Center, National Inst. of Radiological Sciences, Chiba 263-8555, JPN) ,  MARUYAMA Masahiro (Molecular Imaging Center, National Inst. of Radiological Sciences, Chiba 263-8555, JPN) ,  OKAUCHI Takashi (Molecular Imaging Center, National Inst. of Radiological Sciences, Chiba 263-8555, JPN) ,  TOKUNAGA Masaki (Molecular Imaging Center, National Inst. of Radiological Sciences, Chiba 263-8555, JPN) ,  ONO Maiko (Molecular Imaging Center, National Inst. of Radiological Sciences, Chiba 263-8555, JPN) ,  SUHARA Tetsuya (Molecular Imaging Center, National Inst. of Radiological Sciences, Chiba 263-8555, JPN)
Material： Biochimica et Biophysica Acta  (BBA. Biomembranes)
Volume： 1802  Issue： 4  Page： 373-388  Publication year： Apr. 2010 
JST Material Number： B0207A  ISSN： 0005-2728  CODEN： BBBMBS  Document type： Article
Article type： 文献レビュー  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Alzheimer disease ,  *pathological state ,  *visualization ,  animal test ,  *human(primates) ,  *Rodentia ,  medical image ,  amyloid beta-protein ,  tau protein ,  aggregation ,  deposition ,  chain reaction ,  gene ,  mutagenesis ,  gene amplification ,  consecutive reaction ,  transgenic mouse ,  gene manipulation ,  cell death ,  time series ,  biomarker ,  molecule ,  PET(tomography) ,  probe ,  neurotoxin ,  microglia ,  neurotransmitter ,  signal transduction receptor ,  therapeutic planning ,  microscopy ,  biodistribution
Semi thesaurus term： tau gene ,  amyloidogenesis ,  amyloid precursor protein gene ,  cascade reaction ,  knock-in mouse ,  imaging ,  autoagglutination ,  neuroimaging ,  neuronal cell death ,  Models, Animal ,  target molecule

JST classification (4)： Research methods in biological sciences in general  (EA03010K) ,  Central nervous system  (EJ12030F) ,  Proteins and peptides in general  (EB03010N) ,  Nervous system diseases  (GN03000O)

Terms in the title (9)： Alzheimer病 ,  病理 ,  分子過程 ,  可視化 ,  ヒト ,  齧歯類 ,  モデル ,  神経画像 ,  研究