Art

J-GLOBAL ID：201002290360189644   Reference number：10A0004440

Pancreatic Exocrine Duct Cells Give Rise to Insulin-Producing β Cells during Embryogenesis but Not after Birth

膵外分泌管細胞は胚形成中にインシュリン産生β細胞を生じるが生後は同細胞を生じない

Author (23)： SOLAR Myriam (Genomic Programming of Beta Cells Lab., Inst. d’Investigacions Biomediques August Pi i Sunyer, 08036 Barcelona, ESP) ,  SOLAR Myriam (CIBER de Diabetes y Enfermedades Metabolicas Asociadas (CIBERDEM), 08036 Barcelona, ESP) ,  CARDALDA Carina (Genomic Programming of Beta Cells Lab., Inst. d’Investigacions Biomediques August Pi i Sunyer, 08036 Barcelona, ESP) ,  CARDALDA Carina (CIBER de Diabetes y Enfermedades Metabolicas Asociadas (CIBERDEM), 08036 Barcelona, ESP) ,  HOUBRACKEN Isabelle (Diabetes Res. Center, Vrije Universiteit Brussel, Brussels 1090, BEL) ,  HOUBRACKEN Isabelle (JDRF Center for Beta Cell Therapy in Diabetes, Brussels 1090, BEL) ,  MARTIN Merce (Genomic Programming of Beta Cells Lab., Inst. d’Investigacions Biomediques August Pi i Sunyer, 08036 Barcelona, ESP) ,  MARTIN Merce (CIBER de Diabetes y Enfermedades Metabolicas Asociadas (CIBERDEM), 08036 Barcelona, ESP) ,  MAESTRO Miguel Angel (Genomic Programming of Beta Cells Lab., Inst. d’Investigacions Biomediques August Pi i Sunyer, 08036 Barcelona, ESP) ,  MAESTRO Miguel Angel (CIBER de Diabetes y Enfermedades Metabolicas Asociadas (CIBERDEM), 08036 Barcelona, ESP) ,  DE MEDTS Nele (Diabetes Res. Center, Vrije Universiteit Brussel, Brussels 1090, BEL) ,  DE MEDTS Nele (JDRF Center for Beta Cell Therapy in Diabetes, Brussels 1090, BEL) ,  XU Xiaobo (Diabetes Res. Center, Vrije Universiteit Brussel, Brussels 1090, BEL) ,  XU Xiaobo (JDRF Center for Beta Cell Therapy in Diabetes, Brussels 1090, BEL) ,  GRAU Vanessa (Genomic Programming of Beta Cells Lab., Inst. d’Investigacions Biomediques August Pi i Sunyer, 08036 Barcelona, ESP) ,  GRAU Vanessa (CIBER de Diabetes y Enfermedades Metabolicas Asociadas (CIBERDEM), 08036 Barcelona, ESP) ,  HEIMBERG Harry (Diabetes Res. Center, Vrije Universiteit Brussel, Brussels 1090, BEL) ,  HEIMBERG Harry (JDRF Center for Beta Cell Therapy in Diabetes, Brussels 1090, BEL) ,  BOUWENS Luc (Diabetes Res. Center, Vrije Universiteit Brussel, Brussels 1090, BEL) ,  BOUWENS Luc (JDRF Center for Beta Cell Therapy in Diabetes, Brussels 1090, BEL) ,  FERRER Jorge (Genomic Programming of Beta Cells Lab., Inst. d’Investigacions Biomediques August Pi i Sunyer, 08036 Barcelona, ESP) ,  FERRER Jorge (CIBER de Diabetes y Enfermedades Metabolicas Asociadas (CIBERDEM), 08036 Barcelona, ESP) ,  FERRER Jorge (Endocrinology, Hospital Clinic de Barcelona, 08036 Barcelona, ESP)
Material： Developmental Cell  (Dev Cell)
Volume： 17  Issue： 6  Page： 849-860  Publication year： Dec. 15, 2009 
JST Material Number： W1692A  ISSN： 1534-5807  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *Langerhans islet ,  *embryogenesis ,  *morphogenesis ,  gastrin ,  DNA binding protein ,  nuclear protein ,  transcription factor ,  transgenic mouse ,  epithelium ,  pancreatic duct ,  embryo ,  recombinase ,  endothelial cell ,  acinar cell ,  beta-galactosidase ,  intraperitoneal administration ,  adult(development) ,  growth factor ,  ketone ,  lactam ,  urea compound ,  olefin compound ,  phenol ether ,  tertiary amine ,  phenolic compound
Semi thesaurus term： *beta cell ,  *Organogenesis ,  HNF-1 beta ,  Cre recombinase ,  pancreatic acinar cell ,  Endothelial Growth Factors

JST classification (2)： Development(=generation)and differentiation  (EJ16020W) ,  Pancreas  (EJ06050Y)

Substance index (3)： Alloxan ,  Tamoxifen ,  4-Hydroxytamoxifen

Terms in the title (5)： 膵外分泌 ,  胚形成 ,  インシュリン ,  β細胞 ,  細胞