Art

J-GLOBAL ID：201002295150298060   Reference number：10A1754754

Low-molecular Weight Amines Have Marked Potential to Promote Colitis in a Mouse Experimental Model: A Possible Proposal of in vivo Formation of Their Chloramines

低分子量アミンはマウス実験モデルにおいて大腸炎を促進する顕著な能力を有する:それらのクロラミン類のin vivo生成に関する可能な提案

Author (7)： URANO Atsushi (Environmental Toxicology and Carcinogenesis Res. Unit, Nihon Univ. School of Pharmacy) ,  URANO Atsushi (Dep. of Pharmacy, Toho Univ. Sakura Medical Center) ,  NISHIYAMA Kotaro (Environmental Toxicology and Carcinogenesis Res. Unit, Nihon Univ. School of Pharmacy) ,  KATO Koichi (Environmental Toxicology and Carcinogenesis Res. Unit, Nihon Univ. School of Pharmacy) ,  MASAKA Toru (Dep. of Pharmacy, Toho Univ. Sakura Medical Center) ,  TACHIKAWA Mariko (Environmental Toxicology and Carcinogenesis Res. Unit, Nihon Univ. School of Pharmacy) ,  YAMANAKA Kenzo (Environmental Toxicology and Carcinogenesis Res. Unit, Nihon Univ. School of Pharmacy)
Material： Journal of Health Science  (J Health Sci)
Volume： 56  Issue： 6  Page： 690-698 (J-STAGE)  Publication year： 2010 
JST Material Number： S0030A  ISSN： 1344-9702  CODEN： JHSCFD  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *colitis (large intestine) ,...

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JST classification (1)： Digestive system diseases  (GH03000W)

Substance index (1)： Methanamine

Reference (29)：

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• 2) Baumgart, D. C. and Sandborn, W. J. (2007) Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet, 369, 1641-1657.
• 3) Baumgart, D. C. and Carding, S. R. (2007) Inflammatory bowel disease: cause and immunobiology. Lancet, 369, 1627-1640.
• 4) O'Morain, C., Smethurst, P., Levi, A. J. and Peters, T. J. (1983) Biochemical analysis of enzymatic markers of inflammation in rectal biopsies from patients with ulcerative colitis and Crohn's disease. J. Clin. Pathol., 36, 1312-1316.
• 5) Wirtz, S. and Neurath, M. F. (2007) Mouse models of inflammatory bowel disease. Adv. Drug Deliv. Rev., 59, 1073-1083.

Terms in the title (9)： 低分子量 ,  アミン ,  マウス ,  実験モデル ,  大腸炎 ,  促進 ,  能力 ,  クロラミン類 ,  提案