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J-GLOBAL ID：201002298871918254   Reference number：10A0660537

Roles of Oral Bacteria in Cardiovascular Diseases - From Molecular Mechanisms to Clinical Cases: Porphyromonas gingivalis Is the Important Role of Intimal Hyperplasia in the Aorta

心血管疾患における口腔内細菌の役割-分子機序から臨床例まで:Porphyromonas gingivalisは大動脈における内膜過形成の重要な役割をする

Author (2)： HOKAMURA Kazuya (Molecular Imaging Frontier Res. Center, Hamamatsu Univ. School of Medicine, JPN) ,  UMEMURA Kazuo (Dep. of Pharmacology, Hamamatsu Univ. School of Medicine, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 113  Issue： 2  Page： 110-114 (J-STAGE)  Publication year： 2010 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 解説  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Streptococcus mutans ,...
Semi thesaurus term： *Porphyromonas gingivalis ,...

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JST classification (4)： Physiology and pathogenicity of microbial infection  (EG03053T) ,  Cardiovascular system diseases  (GJ03000C) ,  Diseases of tooth and mouth(=oral cavity)  (GT03000G) ,  Infectious diseases,parasitics diseases in general.  (GD01010H)

Reference (9)：

• 1 Meurman JH, Sanz M, Janket S. Oral health, atherosclerosis, and cardiovascular disease. Crit Rev Oral Biol Med. 2004;15:403–413.
• 2 Nakano K, Inaba H, Nomura R, Nemoto H, Takeda M, Yoshioka H, et al. Detection of cariogenic Streptococcus mutans in extirpated heart valve and atheromatous plaque specimens. J Clin Microbiol. 2006;44:3313–3317.
• 3 Zaremba M, Gorska R, Suwalski P, Kowalski J. Evaluation of the incidence of periodontitis-associated bacteria in the atherosclerotic plaque of coronary blood vessels. J Periodontol. 2007;78:322–327.
• 4 Inaba H, Hokamura K, Nakano K, Nomura R, Katayama K, Nakajima A, et al. Upregulation of S100 calcium-binding protein A9 is required for induction of smooth muscle cell proliferation by a periodontal pathogen. FEBS Lett. 2008;583:128–134.
• 5 Hokamura K, Inaba H, Nakano K, Nomura R, Yoshioka H, Taniguchi K, et al. Molecular analysis of aortic intimal hyperplasia caused by Porphyromonas gingivalis infection in mice with endothelial damage. J Periodontal Res. 2010;45:337–344.

Terms in the title (8)： 心血管疾患 ,  口腔内細菌 ,  役割 ,  分子機序 ,  臨床 ,  Porphyromonas ,  大動脈 ,  内膜過形成