Research keywords (3)：
経鼻製剤
, 神経ペプチド
, 精神・神経疾患の病態と治療
Research theme for competitive and other funds (6)：
2024 - 2027 オキシトシンに着目した遅発性産後うつ病の病態解明
2018 - 2021 A physiological role for Neuromedin U in the hippocampal neuronal network and the application
2016 - 2020 Study on the low body weight in young adult rats with neonatal dopamine depletion
2015 - 2018 Pharmacological and translational studies of centrally-acting peptide derivatives specialized in the delivery to the brain by the intranasal administration
2012 - 2015 Pharmacological research on antidepressant-like effects of GLP-2 on refractory depression.
2007 - 2008 Clarification of epileptic mechanism in thalamocortical circuit
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Papers (36)：
Sachie Sasaki-Hamada, Arisa Hara, Yume Tainaka, Sho Satoh, Jun-Ichiro Oka, Hitoshi Ishibashi. Isoform-specific distribution of 14-3-3 proteins in the hippocampus of streptozotocin-induced diabetic rats. Neuroscience letters. 2024. 843. 138027-138027
Junpei Takahashi, Yudai Ueta, Daisuke Yamada, Sachie Sasaki-Hamada, Takashi Iwai, Tomomi Akita, Chikamasa Yamashita, Akiyoshi Saitoh, Jun-Ichiro Oka. Intracerebroventricular administration of oxytocin and intranasal administration of the oxytocin derivative improve β-amyloid peptide (25-35)-induced memory impairment in mice. Neuropsychopharmacology reports. 2022
Sachie Sasaki-Hamada, Emi Sanai, Mariko Kanemaru, Gaku Kamanaka, Jun-Ichiro Oka. Long-term exposure to high glucose induces changes in the expression of AMPA receptor subunits and glutamate transmission in primary cultured cortical neurons. Biochemical and biophysical research communications. 2022. 589. 48-54
Sachie Sasaki-Hamada, Yoshimichi Maeno, Mizuki Yabe, Hitoshi Ishibashi. Neuromedin U modulates neuronal excitability in rat hippocampal slices. Neuropeptides. 2021. 89. 102168-102168
