Rchr
J-GLOBAL ID:201101005381999252   Update date: Apr. 17, 2024

Fujita Kyota

Fujita Kyota
Affiliation and department:
Other affiliations (1):
Research field  (6): Cell biology ,  Neuropathology ,  Neuroscience - general ,  Neuroanatomy and physiology ,  Pharmacology ,  Pharmaceuticals - health and biochemistry
Research keywords  (7): 自閉スペクトラム症 ,  発達障がい ,  ポリグルタミン病 ,  前頭側頭葉変性症 ,  アルツハイマー病 ,  神経変性疾患 ,  中枢神経系
Research theme for competitive and other funds  (9):
  • 2024 - 2026 神経細胞発生と成熟を運命づけるMARCKSL1の機能解明
  • 2022 - 2025 新規動的分子ネットワーク解析で紐解く小脳失調症の超早期病態
  • 2023 - 2025 疾患脳の個性を疑似再現する生体マテリアルの創生
  • 2021 - 2024 神経変性疾患横断的に適応可能な新規中分子医薬品7-Histidine開発
  • 2023 - 2024 脳発達に貢献するMARCKSファミリーの生理学的・病態学的機能探索
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Papers (56):
  • Hidenori Homma, Yuki Yoshioka, Kyota Fujita, Shinichi Shirai, Yuka Hama, Hajime Komano, Yuko Saito, Ichiro Yabe, Hideyuki Okano, Hidenao Sasaki, et al. Dynamic molecular network analysis of iPSC-Purkinje cells differentiation delineates roles of ISG15 in SCA1 at the earliest stage. Communications biology. 2024. 7. 1. 413-413
  • Hidenori Homma, Hikari Tanaka, Kyota Fujita, Hitoshi Okazawa. Necrosis Links Neurodegeneration and Neuroinflammation in Neurodegenerative Disease. International journal of molecular sciences. 2024. 25. 7
  • Yuki Yoshioka, Juliana Bosso Taniguchi, Hidenori Homma, Takuya Tamura, Kyota Fujita, Maiko Inotsume, Kazuhiko Tagawa, Kazuharu Misawa, Naomichi Matsumoto, Masanori Nakagawa, et al. AAV-mediated editing of PMP22 rescues Charcot-Marie-Tooth disease type 1A features in patient-derived iPS Schwann cells. Communications medicine. 2023. 3. 1. 170-170
  • Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A Fischer, Kyota Fujita, Amit L Deshmukh, Rachel J Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, et al. Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability. Cell. 2023. 186. 22. 4898-4919
  • Kyota Fujita, Hidenori Homma, Meihua Jin, Yuki Yoshioka, Xiaocen Jin, Yuko Saito, Hikari Tanaka, Hitoshi Okazawa. Mutant α-synuclein propagates via the lymphatic system of the brain in the monomeric state. Cell reports. 2023. 112962-112962
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MISC (16):
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Lectures and oral presentations  (17):
  • DNA damage repair and neurodegeneration
    (64th Annual Meeting of the Japanese Society of Neurology 2023)
  • 脊髄小脳失調症1型の遺伝子治療
    (第62回日本神経学会学術大会 2021)
  • Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology
    (60th Annual Meeting of the Japanese Society of Neurology 2019)
  • A novel form of necrosis, TRIAD, in Huntington’s disease
    (2018)
  • Developmental YAPdeltaC determines adult pathology in a mouse model of spinocerebellarataxia type 1.
    (第59回日本神経学会学術大会 2018)
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Professional career (1):
  • 博士
Work history (8):
  • 2022/04 - 現在 Kanazawa University Research Center for Child Mental Development
  • 2022/04 - 現在 Tokyo Medical and Dental University
  • 2021/04 - 2022/03 東京医科歯科大学難治疾患研究所 神経病理学分野 講師
  • 2016/04 - 2021/03 Tokyo Medical and Dental University Medical Research Institute
  • 2012/04 - 2016/03 Tokyo Medical and Dental University Medical Research Institute
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Awards (8):
  • 2019/10 - 東京医科歯科大学 優秀研究賞
  • 2019/05 - The Japanese Society of Neurology Best Free Paper Oral Presentation (Basic Research) for JSN members Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology
  • 2019/03 - 東京医科歯科大学難治疾患研究所 最優秀論文賞
  • 2018/03 - 東京医科歯科大学難治疾患研究所 優秀論文賞
  • 2013/03 - 東京医科歯科大学難治疾患研究所 優秀論文賞
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Association Membership(s) (3):
日本神経化学会 ,  THE JAPAN NEUROSCIENCE SOCIETY ,  JAPANESE SOCIETY OF NEUROLOGY
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