Rchr
J-GLOBAL ID:201101006879731121   Update date: May. 11, 2021

Sekimoto Takayuki

セキモト タカユキ | Sekimoto Takayuki
Affiliation and department:
Research field  (2): Tumor diagnostics and therapeutics ,  Molecular biology
Research keywords  (10): Oncogenesis ,  Cell senescence ,  DNA repair ,  DNA damage ,  genomic instability ,  Translesion DNA synthesis ,  Y-family Polymerase ,  Heat shock response ,  DNA damage response ,  Oncogene induced replication stress
Research theme for competitive and other funds  (10):
  • 2019 - 2022 発がんシグナル誘導性複製ストレスへの応答機構を標的とする治療開発
  • 2018 - 2021 発がん性複製ストレス応答分子を標的とした新規がん治療法の開発
  • 2015 - 2018 Analysis of oncogene-induced replication stress response patyways
  • 2015 - 2018 The role of Y-family polymerase in aberrant DNA replication and genomic instability
  • 2012 - 2015 Analysis of replication stress responses caused by oncogenic signals
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Papers (8):
more...
MISC (6):
Lectures and oral presentations  (53):
  • Myc誘導性複製ストレスにおけるグアニン四重鎖構造は治療標的になり得るか
    (第43回日本分子生物学会 2020)
  • がん遺伝子誘導性複製ストレスにおけるグアニン四重鎖構造の役割
    (第42回日本分子生物学会 2019)
  • がん遺伝子誘導性Replication Stress(RS)への応答におけるRAD51を介するフォーク保護機構の役割
    (第41回日本分子生物学会年会 2018)
  • Polη, a Y-family translesion synthesis polymerase, promotes cellular tolerance of Myc-induced replication stress
    (The 4th IMCR Symposium on Endocrine and Metabolism: At the Cutting Edge of Metabolic Regulation Research 2018)
  • 53BP1はHSF1抑制で誘導される細胞老化に関与する
    (第77回日本癌学会学術総会 2018)
more...
Education (3):
  • 2002 - 2006 Kanazawa University Division of Life Sciences
  • 1999 - 2002 Kanazawa University
  • 1995 - 1999 Kanazawa University Department of Biology
Professional career (1):
  • Doctor of Science (Kanazawa University Graduate School)
Work history (3):
  • 2010/05 - 現在 Institute for Molecular and Cellular Regulation, Gunma University Laboratory of Molecular genetics Assistant Professor
  • 2008/04 - 2010/04 Institute for Molecular and Cellular Regulation, Gunma University Laboratory of Molecular genetics Postdoctoral fellow
  • 2006/07 - 2008/03 Institute for Molecular and Cellular Regulation, Gunma University Laboratory of Molecular genetics
Awards (1):
  • 2016 - 日本分子生物学会 優秀ポスター賞 Y-familyポリメラーゼPolηとエンドヌクレアーゼMus81-Eme2複合体は段階的に協調してc-MYCがん遺伝子誘導性複製ストレスを抑制する
Association Membership(s) (2):
Japanese Cancer Association ,  The Molecular Biology Society of Japan
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