REI Yoshimoto

Affiliation and department：
Homepage URL (2)： https://www.setsudai-las.com , https://www.researchgate.net/profile/Rei-Yoshimoto

Research field (2)： Applied molecular and cellular biology , Molecular biology

Research keywords (3)：ノンコーディングRNA , スプライシング , 4.5SH

Research theme for competitive and other funds (10)：

2024 - 2029 Elucidation of the Mechanism of Action of srRNA Controlling Splicing and Identification of Novel srRNAs
2024 - 2027 深部イントロン変異をもつ福山型筋ジストロフィー(FCMD)に対する新規治療法の開発
2023 - 2027 植物病原糸状菌が分泌する細胞外小胞による物質輸送の分子基盤
2022 - 2025 未知の核外輸送機構を短い環状RNAから解明する
2020 - 2023 植物と病原菌間における細胞間コミュニケーションの分子機構の解明

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Papers (24)：

Rei Yoshimoto, Yuta Nakayama, Ikuko Nomura, Ikuko Yamamoto, Yumeka Nakagawa, Shigeyuki Tanaka, Misuzu Kurihara, Yu Suzuki, Takehiko Kobayashi, Hiroko Kozuka-Hata, et al. 4.5SH RNA counteracts deleterious exonization of SINE B1 in mice. Molecular Cell. 2023
Kazuhiro Fukumura, Luca Sperotto, Stefanie Seuß, Hyun-Seo Kang, Rei Yoshimoto, Michael Sattler, Akila Mayeda. SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns. Cell reports. 2023. 113534-113534
Tadahiro Shimazu#, Rei Yoshimoto#, Kaoru Kotoshiba, Takehiro Suzuki, Shogo Matoba, Michiko Hirose, Mai Akakabe, Yoshihiro Sohtome, Mikiko Sodeoka, Atsuo Ogura, et al. Histidine N1-position-specific methyltransferase CARNMT1 targets C3H zinc finger proteins and modulates RNA metabolism. Genes & Development. 2023
Rei Yoshimoto, Shinichi Nakagawa. SINE-derived short noncoding RNAs: their evolutionary origins, molecular mechanisms, and physiological significance. Frontiers in RNA Research. 2023. 1
Daisuke Kaida, Takayuki Satoh, Ken Ishida, Rei Yoshimoto, Kanae Komori. A Truncated Form of the p27 Cyclin-Dependent Kinase Inhibitor Translated from Pre-mRNA Causes G2-Phase Arrest. Molecular and cellular biology. 2022. e0021722

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MISC (4)：

芳本玲, 谷口一郎, 大野睦人, 前田明. 環状RNA(circRNA)の核外輸送機構の解析. 日本RNA学会年会要旨集. 2018. 20th
芳本玲, 谷口一郎, 大野睦人, 前田明. 環状RNA(circRNA)の核外輸送機構の解明. 日本生化学会大会(Web). 2017. 90th
芳本玲, 甲斐田大輔, 古野正朗, 鈴木治和, 林崎良英, 前田明, 中川真一, 吉田稔. RNA制御のケミカルバイオロジースプライシング阻害剤Spliceostatin Aの感受性を決定づけるイントロンの特徴とは?. 日本生化学会大会・日本分子生物学会年会合同大会講演要旨集. 2015. 88回・38回. [4W10-p
芳本玲, 片岡直行, 大川克也, 大野睦人. スプライシング反応後のイントロン-タンパク質複合体の分離と同定. 日本RNA学会年会要旨集. 2009. 11th

Books (2)：

Lectures and oral presentations (21)：

Subsets of human introns using general splicing factors: U2AF-dependent and SPF45-dependent introns as paradigms.
(The 25th Annual Meeting of the RNA Society (online meeting) 2020)
SPF-45 / RBM17 is a novel constitutive splicing factor for a subset of human short introns.
(2019)
A subset of human circRNAs are biosynthesized using mammalian-wide interspersed repeats(MIRs) and exported to cytoplasm via TAP/p15 pathway.
(Eukaryotic mRNA Processing Meeting 2019)
A distinct subset of human short introns with weak pyrimidine tract: U2AF heterodimer is replaced by SPF45/RBM17 as general splicing factor.
(The 24th Annual Meeting of the RNA Society 2019)
U2AF is replaced by SPF45 as general splicing factor to recognize short pyrimidine tract and promotes splicing of human short introns.
(The 20th Takeda Science Foundation Symposium on Bioscience / RNA Neobiology 2019)

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Education (2)：

Professional career (1)：

Work history (4)：

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