Rchr
J-GLOBAL ID：201101023360726793
Update date: Sep. 25, 2024
Hayashi Kumiko
ハヤシ クミコ | Hayashi Kumiko
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
https://www.issp.u-tokyo.ac.jp/
Research field (2)：
Biophysics
, Mathematical physics and basic theory
Research keywords (2)：
Non-equilibrium statistical physics
, Biophysics
Research theme for competitive and other funds (20)：
- 2023 - 2027 Functional expressions of nano-particles in cells by building block assembly methods
- 2023 - 2027 Force measurement for axonal transport by motor proteins using nano-spring and non-equilibrium statistical physics
- 2022 - 2024 Calculation of transport coefficients using a theoretical models of axonal transport in neurons
- 2022 - 2024 Application of extreme value analysis to neuronal cargo transport
- 2022 - 2023 Non-invasive force measurement method applied to axonal transport in human iPSC derived neurons
- 2018 - 2022 Image analysis of axonal transport based on non-equilibrium statistical mechanics toward medical application
- 2021 - Non-invasive force measurement method applied to axonal transport by KIF1A in human iPSC derived neurons
- 2017 - 2020 Optical control and fluctuation measurement of the number of motor proteins transporting mitochondria
- 2018 - 2019 Development and commercialization of molecular motor counter software
- 2015 - 2019 Non-invasive force measurement using fluctuation applied to organelle transport in neurons
- 2016 - 2018 柔らかな分子のゆらぎと外場応答:非平衡統計力学関係式の応用
- 2014 - 2018 非平衡確率過程模型の恒等式群と医療・美容
- 2017 - 2018 複数のタンパク質モーターによる協同的な軸索輸送と軸索成長・再生 (原文: Quantal modes of organelle transport by motor proteins during axonal growth and regeneration)
- 2014 - 2016 少数のタンパク質モーターによる神経細胞オルガネラ輸送の協同的メカニズムの解明
- 2014 - 2016 タンパク質モーターによるオルガネラ輸送への非平衡統計力学関係式の応用
- 2012 - 2014 非平衡統計力学による細胞内ゆらぎ測定
- 2011 - 2013 統計力学基礎論•非平衡統計力学のブレークスルーによる一分子測定理論の創出
- 2007 - 2010 粗視化タンパク質モデルの数値実験による細胞機能の再現と定量的統計理論の構築
- 2010 - 粗視化タンパク質モデルの数値実験による細胞機能の再現と定量的統計理論の構築
- 2005 - 2007 局所平衡を大きく破る現象に対する統計理論の測定量関係式からの構築
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Papers (34)：
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Kumiko Hayashi, Nobumichi Takamatsu, Shunki Takaramoto. Extreme-value analysis in nano-biological systems: Applications and Implications. Biophysical Reviews. 2024
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T. Naoi, Y. Kagawai, K. Nagino, S. Niwa, K. Hayashi. Extreme Value Analysis of Intracellular Cargo Transport by Motor Proteins. Communications Physics. 2024
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Kumiko Hayashi, Kazuo Sasaki. Number of kinesins engaged in axonal cargo transport: A novel biomarker for neurological disorders. Neuroscience Research. 2023. 197. 25-30
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Ryota Kameda, Taisei Suzuki, Ikumi Kato, Keishi Suga, Kanako Watanabe, Kimiko Nagino, Kumiko Hayashi, Satoshi Arai, Daisuke Nagao. Intracellular Magnetic Control over the Reversible Assembly of Silica-Based Magnetic Composite Particles for Photothermal Therapy. ACS Applied Nano Materials. 2023. 6. 3873-3883
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Y. Anazawa, T. Kita, R. Iguchi, K. Hayashi, S. Niwa. De novo disease-associated mutations in KIF1A dominant negatively inhibit axonal transport of synaptic vesicle precursors. Proceedings of the National Academy of Science of the United States of America. 2021. 119. 2113795119
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MISC (10)：
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Kumiko Hayashi, Chun-Biu Li. Commentary to “Application of Non-equilibrium physics”: a session of the 21th IUPAB Congress 2024, Kyoto, Japan. Biophysical Reviews. 2024
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Tomohiro Shima, Kumiko Hayashi. The third Japan-U.S. symposium on motor proteins and associated single-molecule biophysics. Biophysics and Physicobiology. 2023
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Kumiko Hayashi. Axonal transport by multiple kinesins. Medical Science Digest. 2023. 49. 52-53
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K. Hayashi, J. J. Keya. Japan-US symposium on motor proteins and associated single-molecule biophysics. Biophysics and Physicobiology. 2022. 19. e190030
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K. Hayashi, S. Niwa. Japan-US symposium on cytoskeletal motor proteins and their associated proteins. Biophysics and Physicobiology. 2021. 18. 241-243
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Professional career (1)：
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