Rchr
J-GLOBAL ID:201101024180670923   Update date: Mar. 21, 2024

Yamaguchi Yoshiki

ヤマグチ ヨシキ | Yamaguchi Yoshiki
Affiliation and department:
Job title: 教授
Research field  (2): Pharmaceuticals - chemistry and drug development ,  Pharmaceuticals - analytical and physicochemistry
Research keywords  (13): データベース ,  質量分析 ,  構造生物学 ,  レクチン ,  ダイナミクス ,  生物物理 ,  脳神経疾患 ,  安定同位体標識 ,  分子認識 ,  糖タンパク質 ,  薬学 ,  NMR ,  糖鎖
Research theme for competitive and other funds  (39):
  • 2022 - 2025 Elucidation of molecular mechanism for IgG levels regulated by L-fucose
  • 2019 - 2024 Biology of sugar-alcohol modification in glycan
  • 2019 - 2022 Study on structure and interaction of branched glycans
  • 2018 - 2021 新規リビトールリン酸糖鎖の修飾機序の解明と生理活性の治療応用
  • 2016 - 2021 Chemical Biology of ER Related Glycan Modifications
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Papers (322):
  • Shiho Ohno, Noriyoshi Manabe, Jun Uzawa, Yoshiki Yamaguchi. Comparative Conformational Analysis of Acyclic Sugar Alcohols Ribitol, Xylitol and d-Arabitol by Solution NMR and Molecular Dynamics Simulations. Molecules. 2024. 29. 5. 1072-1072
  • Ryoka Kokubu, Shiho Ohno, Noriyoshi Manabe, Yoshiki Yamaguchi. Solution NMR Analysis of O-Glycopeptide-Antibody Interaction. Methods in Molecular Biology. 2024. 321-327
  • Ryoka Kokubu, Shiho Ohno, Noriyoshi Manabe, Yoshiki Yamaguchi. Molecular Dynamics Simulation and Docking of MUC1 O-Glycopeptide. Methods in Molecular Biology. 2024. 373-379
  • Shunli Pan, Noriyoshi Manabe, Shiho Ohno, Sachiko Komatsu, Tsutomu Fujimura, Yoshiki Yamaguchi. Each N-glycan on human IgA and J-chain uniquely affects oligomericity and stability. Biochimica et Biophysica Acta (BBA) - General Subjects. 2024. 1868. 2. 130536-130536
  • Shiho Ohno, Noriyoshi Manabe, Yoshiki Yamaguchi. Prediction of protein structure and AI. Journal of Human Genetics. 2024
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MISC (126):
  • 西原祥子, 木下聖子, 栂谷内晶, 細田正恵, 伊藤和義, 山口芳樹, 真鍋法義, 大野詩歩, 稲森啓一郎, 井ノ口仁一, et al. Comprehensive extraction and analysis of the whole human glycan-related gene variant. 日本糖質学会年会要旨集. 2021. 40th
  • 大野 礼一, 田中 誠太郎, 伴 郁穂, 勝田 奈那, 富永 悠幹, 谷口 直之, 山口 芳樹, 伊藤 恵実, 永井 竜児. 糖尿病ラット水晶体におけるポリオール経路由来新規AGEsの蓄積評価. 日本抗加齢医学会総会プログラム・抄録集. 2020. 20回. 196-196
  • 真鍋良幸, 真鍋良幸, MARCHETTI Roberta, 高倉陽平, 長崎政裕, 二瓶渉, 武部智之, 田中克典, 田中克典, 樺山一哉, et al. Identification of core fucose containing N-glycan recognition lectin. 日本糖質学会年会要旨集. 2020. 39th
  • 大野詩歩, 真鍋法義, 山口拓実, 鵜澤洵, 山口芳樹, 山口芳樹. 非環状の糖鎖成分リビトールの動的構造の解析. 日本薬学会東北支部大会講演要旨集. 2020. 59th
  • 大野詩歩, 真鍋法義, 山口拓実, 鵜澤洵, 山口芳樹, 山口芳樹. Conformational analysis of acyclic sugar ribitol by NMR and molecular dynamics simulation. 日本糖質学会年会要旨集. 2020. 39th
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Books (19):
  • Adv. Chem. Res. : Mannose as a component of glycans : Structure, dynamics and interaction.
    2020
  • Curr Top Microbiol Immunol. : Structural Aspects of Carbohydrate Recognition Mechanisms of C-Type Lectins.
    2019
  • Glycoscience: Basic Science to Applications
    2019 ISBN:9789811358555
  • Glycoscience: Basic Science to Applications
    2019 ISBN:9789811358555
  • Glycoscience: Basic Science to Applications
    2019 ISBN:9789811358555
more...
Work history (7):
  • 2021/04 - 現在 Tohoku Medical and Pharmaceutical University Division of Structural Glycobiology Professor
  • 2019/04 - 2021/03 Tohoku Medical and Pharmaceutical University Faculty of Pharmaceutical Sciences
  • 2018/04 - 2019/03 理化学研究所 伊藤細胞制御化学研究室 研究員
  • 2007/10 - 2018/03 理化学研究所 糖鎖構造生物学研究チーム チームリーダー
  • 2001/06 - 2007/09 Nagoya City University Graduate School of Pharmaceutical Sciences
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Association Membership(s) (11):
Society for Glycobiology ,  ASBMB ,  THE BIOPHYSICAL SOCIETY OF JAPAN ,  PROTEIN SCIENCE SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  THE SPECTROSCOPICAL SOCIETY OF JAPAN ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE BIOCHEMICAL SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE NUCLEAR MAGNETIC RESONANCE SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH
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