Rchr
J-GLOBAL ID:201101025343013271
Update date: Nov. 16, 2024
Asai Teigo
アサイ テイゴ | Asai Teigo
Affiliation and department:
Research field (3):
Applied microbiology
, Bioorganic chemistry
, Environmental and pharmaceutical development resources
Research theme for competitive and other funds (13):
- 2023 - 2028 アフリカでの薬剤耐性マラリア封じ込め戦略構築のための先進的国際共同フィールド研究
- 2022 - 2026 合成生物学的手法を基盤とする活性天然物の構造展開研究
- 2021 - 2024 大規模ゲノム再編成を基盤とする革新的天然物創製法の開発
- 2020 - 2023 -
- 2019 - 2022 Development of therapeutics for intractable infections using diverse natural products combined with stress-inductive biosynthesis and chemical modification
- 2019 - 2021 糸状菌未開拓マクロライド生合成経路の再構築と再設計による新規抗生物質シーズの開拓
- 2018 - 2021 Discovery of novel peptide natural product with anti bacterial activities
- 2017 - 2021 Post-genomic natural discovery focused on unique polyketide synthase genes
- 2017 - 2019 麹菌異種発現系を基盤とする人工代謝経路の構築と抗がん活性擬天然物の創生研究
- 2016 - 2019 Novel screenings for unmet medical needs with innovative new natural product derived compounds
- 2014 - 2017 Generation of new drug seed natural products from entomopathogenic microorganism by activating silent biosynthetic gene clusters
- 2013 - 2015 新規生合成マシナリー開拓を志向した未利用遺伝子活性化による天然物構造多様性の創出
- 2011 - 2012 Production of novel fungal secondary metabolites by epigenetically activating the silent biosynthetic gene clusters.
Show all
Papers (54):
-
Soya Koremura, Akihiro Sugawara, Yohei Morishita, Taro Ozaki, Teigo Asai. Semi-synthesis of a DNA-Tagged Polyketide-Peptide Hybrid Macrocycle Using a Biosynthetically Prepared Fungal Macrolide as a Synthetic Component. Organic letters. 2024. 26. 42. 9151-9156
-
Fumito Sato, Terutaka Sonohara, Shunta Fujiki, Akihiro Sugawara, Yohei Morishita, Taro Ozaki, Teigo Asai. Genome mining of labdane-related diterpenoids: Discovery of the two-enzyme pathway leading to (-)-sandaracopimaradiene in the fungus Arthrinium sacchari. Beilstein Journal of Organic Chemistry. 2024
-
Yue Shi, Taro Ozaki, Akihiro Sugawara, Yohei Morishita, Yu Pei Tan, Roger G. Shivas, Rohan A. Davis, Teigo Asai. A new 3,6-dialkyl-α-pyrone produced by the heterologous expression of a PKS-NRPS hybrid enzyme derived from a Pestalotiopsis endophyte. Tetrahedron Letters. 2024. 134. 154865-154865
-
Sho Furumura, Taro Ozaki, Akihiro Sugawara, Yohei Morishita, Kento Tsukada, Tatsuya Ikuta, Asuka Inoue, Teigo Asai. Identification and Functional Characterization of Fungal Chalcone Synthase and Chalcone Isomerase. Journal of Natural Products. 2023. 86. 2. 398-405
-
Yuto Homma, Akihiro Sugawara, Yohei Morishita, Kento Tsukada, Taro Ozaki, Teigo Asai. Discovery of a Cyclic Depsipeptide from Chaetomium mollipilium by the Genome Mining Approach. Organic letters. 2022. 24. 19. 3504-3509
more...
MISC (59):
-
根岸透子, 尾崎太郎, 菅原章公, 森下陽平, 浅井禎吾. Heterologous production of the amatoxin precursor in Aspergillus oryzae. 日本薬学会年会要旨集(Web). 2024. 144th
-
岡本春太, 尾崎太郎, 森下陽平, 菅原章公, 浅井禎吾. Functional analysis of UstYa family proteins in the biosynthesis of cyclochlorotine derivatives. 日本薬学会年会要旨集(Web). 2024. 144th
-
長谷川智哉, 森下陽平, 菅原章公, 尾崎太郎, 浅井禎吾. Genome mining-based discovery of resorcinolic macrolides from Cytospora sp. 日本薬学会年会要旨集(Web). 2024. 144th
-
惟村壮哉, 菅原章公, 森下陽平, 尾崎太郎, 浅井禎吾. Synthesis of polyketide-peptide hybrid-like macrocyclic compounds on DNA aimed at constructing DNA-encoded libraries. 日本薬学会年会要旨集(Web). 2024. 144th
-
関谷光留, 佐藤史都, 菅原章公, 森下陽平, 尾崎太郎, 浅井禎吾. Chemoenzymatic synthesis of the fluorinated dolabellane skeleton for expanding functional diversity. 日本薬学会年会要旨集(Web). 2024. 144th
more...
Professional career (1):
Work history (3):
- 2019/10 - 現在 Tohoku University Graduate School of Pharmaceutical Sciences Professor
- 2016/03 - 2019/09 The University of Tokyo Department of Life Sciences, Graduate School of Arts and Sicences
- 2009/07 - 2016/02 Tohoku University Graduate School of Pharmaceutical Sciences Assistant Professor
Association Membership(s) (1):
Return to Previous Page