Rchr
J-GLOBAL ID:201101025343013271
Update date: Jul. 19, 2024
Asai Teigo
アサイ テイゴ | Asai Teigo
Affiliation and department:
Research field (3):
Applied microbiology
, Bioorganic chemistry
, Environmental and pharmaceutical development resources
Research theme for competitive and other funds (13):
- 2023 - 2028 アフリカでの薬剤耐性マラリア封じ込め戦略構築のための先進的国際共同フィールド研究
- 2022 - 2026 合成生物学的手法を基盤とする活性天然物の構造展開研究
- 2021 - 2024 大規模ゲノム再編成を基盤とする革新的天然物創製法の開発
- 2020 - 2023 -
- 2019 - 2022 Development of therapeutics for intractable infections using diverse natural products combined with stress-inductive biosynthesis and chemical modification
- 2019 - 2021 糸状菌未開拓マクロライド生合成経路の再構築と再設計による新規抗生物質シーズの開拓
- 2018 - 2021 Discovery of novel peptide natural product with anti bacterial activities
- 2017 - 2021 Post-genomic natural discovery focused on unique polyketide synthase genes
- 2017 - 2019 麹菌異種発現系を基盤とする人工代謝経路の構築と抗がん活性擬天然物の創生研究
- 2016 - 2019 Novel screenings for unmet medical needs with innovative new natural product derived compounds
- 2014 - 2017 Generation of new drug seed natural products from entomopathogenic microorganism by activating silent biosynthetic gene clusters
- 2013 - 2015 新規生合成マシナリー開拓を志向した未利用遺伝子活性化による天然物構造多様性の創出
- 2011 - 2012 Production of novel fungal secondary metabolites by epigenetically activating the silent biosynthetic gene clusters.
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Papers (53):
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Fumito Sato, Terutaka Sonohara, Shunta Fujiki, Akihiro Sugawara, Yohei Morishita, Taro Ozaki, Teigo Asai. Genome mining of labdane-related diterpenoids: Discovery of the two-enzyme pathway leading to (-)-sandaracopimaradiene in the fungus Arthrinium sacchari. Beilstein Journal of Organic Chemistry. 2024
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Yue Shi, Taro Ozaki, Akihiro Sugawara, Yohei Morishita, Yu Pei Tan, Roger G. Shivas, Rohan A. Davis, Teigo Asai. A new 3,6-dialkyl-α-pyrone produced by the heterologous expression of a PKS-NRPS hybrid enzyme derived from a Pestalotiopsis endophyte. Tetrahedron Letters. 2024. 134. 154865-154865
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Sho Furumura, Taro Ozaki, Akihiro Sugawara, Yohei Morishita, Kento Tsukada, Tatsuya Ikuta, Asuka Inoue, Teigo Asai. Identification and Functional Characterization of Fungal Chalcone Synthase and Chalcone Isomerase. Journal of Natural Products. 2023. 86. 2. 398-405
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Yuto Homma, Akihiro Sugawara, Yohei Morishita, Kento Tsukada, Taro Ozaki, Teigo Asai. Discovery of a Cyclic Depsipeptide from Chaetomium mollipilium by the Genome Mining Approach. Organic letters. 2022. 24. 19. 3504-3509
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Yohei Morishita, Kento Tsukada, Kazuma Murakami, Kazuhiro Irie, Teigo Asai. Synthetic Biology-Based Discovery of Diterpenoid Pyrones from the Genome of Eupenicillium shearii. Journal of natural products. 2022. 85. 2. 384-390
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MISC (46):
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SHI Yue, 菅原章公, 尾崎太郎, 浅井禎吾. Biosynthetic study of pestalactams. 日本薬学会年会要旨集(Web). 2023. 143rd
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松井洸人, 塚田健人, 菅原章公, 尾崎太郎, 浅井禎吾. Biosynthetic study on chaetophenols produced by a fungus Chaetomium indicum. 日本薬学会年会要旨集(Web). 2023. 143rd
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LI Yi, 菅原章公, 尾崎太郎, 浅井禎吾. Genome mining-based discovery of fungal macrolides from Aspergillus petrakii. 日本薬学会年会要旨集(Web). 2023. 143rd
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廣川瑞樹, 森下陽平, 塚田健人, 菅原章公, 尾崎太郎, 浅井禎吾. Biosynthetic study of hymeglusin. 日本薬学会年会要旨集(Web). 2023. 143rd
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本間悠人, 菅原章公, 森下陽平, 塚田健人, 尾崎太郎, 浅井禎吾. Structure elucidation and biosynthetic study of chaetodepsipeptins. 日本薬学会年会要旨集(Web). 2023. 143rd
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Professional career (1):
Work history (3):
- 2019/10 - 現在 Tohoku University Graduate School of Pharmaceutical Sciences Professor
- 2016/03 - 2019/09 The University of Tokyo Department of Life Sciences, Graduate School of Arts and Sicences
- 2009/07 - 2016/02 Tohoku University Graduate School of Pharmaceutical Sciences Assistant Professor
Association Membership(s) (1):
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