Rchr
J-GLOBAL ID:201101025343013271
Update date: Dec. 09, 2025
Asai Teigo
アサイ テイゴ | Asai Teigo
Affiliation and department:
Research field (2):
Environmental and pharmaceutical development resources
, Bioorganic chemistry
Research theme for competitive and other funds (17):
- 2023 - 2028 アフリカでの薬剤耐性マラリア封じ込め戦略構築のための先進的国際共同フィールド研究
- 2024 - 2027 天然物探索に利用可能な大規模ゲノム再編成を鍵とする休眠遺伝子活性化法の開発
- 2022 - 2026 合成生物学的手法を基盤とする活性天然物の構造展開研究
- 2021 - 2024 大規模ゲノム再編成を基盤とする革新的天然物創製法の開発
- 2020 - 2023 -
- 2019 - 2022 Development of therapeutics for intractable infections using diverse natural products combined with stress-inductive biosynthesis and chemical modification
- 2021 - 2022 合成生物学を基盤とする革新的天然物創製研究
- 2019 - 2021 糸状菌未開拓マクロライド生合成経路の再構築と再設計による新規抗生物質シーズの開拓
- 2018 - 2021 Discovery of novel peptide natural product with anti bacterial activities
- 2017 - 2021 Post-genomic natural discovery focused on unique polyketide synthase genes
- 2017 - 2019 麹菌異種発現系を基盤とする人工代謝経路の構築と抗がん活性擬天然物の創生研究
- 2016 - 2019 Novel screenings for unmet medical needs with innovative new natural product derived compounds
- 2014 - 2017 Generation of new drug seed natural products from entomopathogenic microorganism by activating silent biosynthetic gene clusters
- 2013 - 2015 新規生合成マシナリー開拓を志向した未利用遺伝子活性化による天然物構造多様性の創出
- 2011 - 2012 Production of novel fungal secondary metabolites by epigenetically activating the silent biosynthetic gene clusters.
- 2011 - 2011 低分子阻害剤を用いたエピジェネティック制御による新規有用二次代謝物の創出
- 2010 - 2010 エピジェネティックな遺伝子発現制御を利用した新規有用天然物の創出法の開発
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Papers (61):
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Kento Tsukada, Fumito Sato, Taro Matsuyama, Ryo Matsuda, Taro Ozaki, Yohei Morishita, Sho Furumura, Yuto Homma, Hikaru Sekiya, Akihiro Sugawara, et al. Vinigrol Tricyclic Scaffold Biosynthesis Employs an Atypical Terpene Cyclase and a Multipotent Cyclization Cascade. Journal of the American Chemical Society. 2025
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Yue Shi, Taro Ozaki, Yohei Morishita, Tohru Taniguchi, Hiroyasu Sato, Yoshitaka Aoyama, Akihiro Sugawara, Kaho Numata, Tomoya Fuse, Ryo Matsuda, et al. Genome Mining-Based Discovery of Pyrano[2,3-c]pyrrole Type Natural Products Possessing Alkyl Side Chain with Branched Methyl Groups. Organic letters. 2025. 27. 31. 8580-8585
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Mizuki Hirokawa, Taro Ozaki, Kento Tsukada, Akihiro Sugawara, Yohei Morishita, Teigo Asai. Ketosynthase Domain Catalyzes β-Lactonization in the Biosynthesis of the HMG-CoA Synthase Inhibitor Hymeglusin. Journal of the American Chemical Society. 2025. 147. 29. 25136-25141
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Yura Sato, Yohei Morishita, Yuto Homma, Akihiro Sugawara, Ashaimaa Y Moussa, Ahmed M Elissawy, Abdel Nasser B Singab, Taro Ozaki, Teigo Asai. Biosynthesis of Circumdatins Employs an Anthranilate Tailoring Pathway for NRPS Substrate Supplies. Organic letters. 2025. 27. 26. 7170-7175
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Chihiro Kadooka, Kosuke Izumitsu, Teigo Asai, Kentaro Hiramatsu, Kazuki Mori, Kayu Okutsu, Yumiko Yoshizaki, Kazunori Takamine, Masatoshi Goto, Hisanori Tamaki, et al. Overexpression of the RNA-binding protein NrdA affects global gene expression and secondary metabolism in Aspergillus species. mSphere. 2025. 10. 2. e0084924
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MISC (182):
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浅井禎吾. Genome mining-based Natural product research. 日本薬学会年会要旨集(Web). 2025. 145th
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関谷光留, 佐藤史都, 菅原章公, 菅原章公, 尾崎太郎, 森下陽平, 浅井禎吾. Enzyme reaction of diterpene cyclases using fluorinated GGPP and analysis of reaction products. 日本薬学会年会要旨集(Web). 2025. 145th
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佐藤柚良, 森下陽平, 菅原章公, 尾崎太郎, 浅井禎吾. Identification and functional investigation of the circumdatin biosynthetic gene cluster. 日本薬学会年会要旨集(Web). 2025. 145th
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布施智也, 小此木亮介, 森下陽平, 尾崎太郎, 菅原章公, 浅井禎吾. The heterologous expression in Aspergillus oryzae and the metabolites analysis to achieve the heterologous production of the antitumor polyketides, colletofragarones. 日本薬学会年会要旨集(Web). 2025. 145th
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平林薫歩, 尾崎太郎, 森下陽平, 菅原章公, 浅井禎吾. Heterologous production of glycyrrhizin in Aspergillus oryzae. 日本薬学会年会要旨集(Web). 2025. 145th
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Professional career (1):
Work history (3):
- 2019/10 - 現在 Tohoku University Graduate School of Pharmaceutical Sciences Professor
- 2016/03 - 2019/09 The University of Tokyo Department of Life Sciences, Graduate School of Arts and Sicences
- 2009/07 - 2016/02 Tohoku University Graduate School of Pharmaceutical Sciences Assistant Professor
Association Membership(s) (2):
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