Rchr
J-GLOBAL ID:201101033614192854   Update date: May. 12, 2021

Gotoh Yukiko

ゴトウ ユキコ | Gotoh Yukiko
Affiliation and department:
Homepage URL  (1): http://kaken.nii.ac.jp/ja/r/70252525
Research field  (8): Cell biology ,  Neuroscience - general ,  Genomics ,  Developmental biology ,  Cell biology ,  Systems genomics ,  Genomics ,  Neuroscience - general
Research keywords  (35): 神経幹細胞 ,  アポトーシス ,  MAPキナーゼ ,  細胞運動 ,  カスペース ,  ニューロン ,  がん遺伝子 ,  神経細胞 ,  PI3キナーゼ ,  細胞生存 ,  細胞死 ,  細胞極性 ,  上皮間葉転換 ,  Scratch ,  増殖因子 ,  ニューロンサブタイプ ,  包括脳ネットワーク」 ,  JNK ,  MST1 ,  MAPKK ,  p38 ,  Bax ,  PDK1 ,  Mdm2 ,  SEKI ,  XMEK2 ,  Ras ,  MST ,  Cdc42 ,  Rho ,  actin, ,  増殖シグナル伝達 ,  PAK ,  AKT ,  生存シグナル
Research theme for competitive and other funds  (21):
  • 2019 - 2025 Regulation of embryonic neural stem cells and its relation to postnatal brain development and autism spectrum disorder
  • 2016 - 2021 神経幹細胞の発生タイマー実行因子の解析
  • 2015 - 2020 神経幹細胞の分化運命を決める統合的メカニズムの解明
  • 2014 - 2020 Homeostatic Regulation and Dysregulation of Neural Stem Cells under Physiological and Pathological Challenges
  • 2015 - 2017 神経幹細胞の発生時期特異的な運命決定機構の解明
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Papers (165):
  • Naoya Yuizumi, Yujin Harada, Takaaki Kuniya, Takehiko Sunabori, Masato Koike, Masaki Wakabayashi, Yasushi Ishihama, Yutaka Suzuki, Daichi Kawaguchi, Yukiko Gotoh. Maintenance of neural stem - progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Stem Cells. 2021
  • Hanae Omiya, Shima Yamaguchi, Tomoyuki Watanabe, Takaaki Kuniya, Yujin Harada, Daichi Kawaguchi, Yukiko Gotoh. BMP signaling suppresses Gemc1 expression and ependymal differentiation of mouse telencephalic progenitors. Scientific Reports. 2021. 11. 1
  • Hikaru Eto, Yusuke Kishi, Nayuta Yakushiji-Kaminatsui, Hiroki Sugishita, Shun Utsunomiya, Haruhiko Koseki, Yukiko Gotoh. The Polycomb group protein Ring1 regulates dorsoventral patterning of the mouse telencephalon. Nature Communications. 2020. 11. 1
  • Saeko Aoyama-Ishiwatari, Tomohiko Okazaki, Shun-ichiro Iemura, Tohru Natsume, Yasushi Okada, Yukiko Gotoh. NUDT21 Links Mitochondrial IPS-1 to RLR-Containing Stress Granules and Activates Host Antiviral Defense. The Journal of Immunology. 2020. 206. 1. 154-163
  • Naohiro Kuwayama, Yusuke Kishi, Yurie Maeda, Yurie Nishiumi, Yutaka Suzuki, Haruhiko Koseki, Yusuke Hirabayashi, Yukiko Gotoh. In utero gene transfer system for embryos before neural tube closure reveals a role for Hmga2 in the onset of neurogenesis. bioRxiv. 2020
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MISC (44):
Lectures and oral presentations  (371):
  • Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module, Secrets of stem cells underlying longevity and persistent growth in plants
    (Secrets of stem cells underlying longevity and persistent growth in plants 2021)
  • 中枢神経炎症における抗ウイルス応答使い分け機構の役割の解析
    (日本薬学会 第141年会 2021)
  • Roles of cell cycle inhibition in the genesis of adult neural stem cells.
    (2021)
  • 胎生期神経系前駆細胞の運命制御におけるリソソームの新規機能の解明
    (第14回神経発生討論会 2021)
  • リカレンスプロットを使用した胎生初期胚クロマチン構造の再構成
    (第43回日本分子生物学会年会 2020)
more...
Work history (3):
  • 2013/10 - The University of Tokyo Graduate School of Pharmaceutical Sciences
  • 2005/04 - 2013/09 The University of Tokyo Institute of Molecular and Cellular Biosciences
  • 1999/03 - 2005/03 The University of Tokyo Institute of Molecular and Cellular Biosciences
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