Gotoh Yukiko

ゴトウユキコ | Gotoh Yukiko

Affiliation and department：
Homepage URL (1)： http://kaken.nii.ac.jp/ja/r/70252525

Research field (8)： Cell biology , Neuroscience - general , Genomics , Developmental biology , Cell biology , Systems genomics , Genomics , Neuroscience - general

Research keywords (35)：神経幹細胞 , アポトーシス , MAPキナーゼ , 細胞運動 , カスペース , ニューロン , がん遺伝子 , 神経細胞 , PI3キナーゼ , 細胞生存 , 細胞死 , 細胞極性 , 上皮間葉転換 , Scratch , 増殖因子 , ニューロンサブタイプ , 包括脳ネットワーク」 , JNK , MST1 , MAPKK , p38 , Bax , PDK1 , Mdm2 , SEKI , XMEK2 , Ras , MST , Cdc42 , Rho , actin, , 増殖シグナル伝達 , PAK , AKT , 生存シグナル

Research theme for competitive and other funds (21)：

2019 - 2025 Regulation of embryonic neural stem cells and its relation to postnatal brain development and autism spectrum disorder
2016 - 2021 神経幹細胞の発生タイマー実行因子の解析
2015 - 2020 神経幹細胞の分化運命を決める統合的メカニズムの解明
2014 - 2020 Homeostatic Regulation and Dysregulation of Neural Stem Cells under Physiological and Pathological Challenges
2015 - 2017 神経幹細胞の発生時期特異的な運命決定機構の解明

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Papers (168)：

Yoshito Hirata, Yuki Kitanishi, Hiroki Sugishita, Yukiko Gotoh. Fast reconstruction of an original continuous series from a recurrence plot. Chaos: An Interdisciplinary Journal of Nonlinear Science. 2021. 31. 12. 121101-121101
Yujin Harada, Mayumi Yamada, Itaru Imayoshi, Ryoichiro Kageyama, Yutaka Suzuki, Takaaki Kuniya, Shohei Furutachi, Daichi Kawaguchi, Yukiko Gotoh. Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module. Nature Communications. 2021. 12. 1
Shun Utsunomiya, Yusuke Kishi, Masafumi Tsuboi, Daichi Kawaguchi, Yukiko Gotoh, Manabu Abe, Kenji Sakimura, Kazuma Maeda, Hiroshi Takemoto. Ezh1 regulates expression of Cpg15/Neuritin in mouse cortical neurons. Drug discoveries & therapeutics. 2021. 15. 2. 55-65
Naoya Yuizumi, Yujin Harada, Takaaki Kuniya, Takehiko Sunabori, Masato Koike, Masaki Wakabayashi, Yasushi Ishihama, Yutaka Suzuki, Daichi Kawaguchi, Yukiko Gotoh. Maintenance of neural stem - progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Stem Cells. 2021
Hanae Omiya, Shima Yamaguchi, Tomoyuki Watanabe, Takaaki Kuniya, Yujin Harada, Daichi Kawaguchi, Yukiko Gotoh. BMP signaling suppresses Gemc1 expression and ependymal differentiation of mouse telencephalic progenitors. Scientific Reports. 2021. 11. 1. 613-613

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MISC (42)：

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Lectures and oral presentations (426)：

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(2023)
Reprogramming of cortical neuron subtypes by genetic and epigenetic Manipulation
(International Symposium on Neural Development and Diseases 2023)
Regulation of neural stem cell fate
(International Symposium on Neural Development and Diseases 2023)
Reprogramming of upper layer cortical neurons into neurons with deep layer characteristics by combinatorial expression of transcription factors
(2023)
Chromatin level regulation of neural stem cell fate
(OIST workshop_ Nervous System Assembly 2023)

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Work history (3)：

2013/10 - The University of Tokyo Graduate School of Pharmaceutical Sciences
2005/04 - 2013/09 The University of Tokyo Institute of Molecular and Cellular Biosciences
1999/03 - 2005/03 The University of Tokyo Institute of Molecular and Cellular Biosciences

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