J-GLOBAL ID:201101033614192854   Update date: Oct. 17, 2019

Yukiko Gotoh

ゴトウ ユキコ | Yukiko Gotoh
Affiliation and department:
Homepage URL  (1): http://kaken.nii.ac.jp/ja/r/70252525
Research field  (7): Cell biology ,  Neurochemistry/Neuropharmacology ,  Genome biology ,  Basic genome science ,  Developmental biology ,  Cell biology ,  Neurochemistry/Neuropharmacology
Research keywords  (17): JNK ,  Scratch ,  MST1 ,  MAPKK ,  p38 ,  Bax ,  PDK1 ,  Mdm2 ,  SEKI ,  XMEK2 ,  Ras ,  MST ,  Cdc42 ,  Rho ,  actin, ,  AKT ,  PAK
Research theme for competitive and other funds  (9):
  • 2019 - 2025 Regulation of embryonic neural stem cells and its relation to postnatal brain development and autism spectrum disorder
  • 2014 - 2020 Homeostatic Regulation and Dysregulation of Neural Stem Cells under Physiological and Pathological Challenges
  • 2005 - 2009 Functions of protein kinases in tumorigenesis
  • 2006 - 2007 Regulation of neocortical neuronal migration by the PDKl-Akt pathway
  • 2004 - 2005 Activation and functions of the PDK1-Akt pathway in regulation of cell motility
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Papers (148):
  • Tanaka H, Okazaki T, Aoyama S, Yokota M, Koike M, Okada Y, Fujiki Y, Gotoh Y. Peroxisomes control mitochondrial dynamics and the mitochondrion-dependent apoptosis pathway. Journal of cell science. 2019. 132. 11
  • Tsuboi M, Kishi Y, Yokozeki W, Koseki H, Hirabayashi Y, Gotoh Y. Ubiquitination-Independent Repression of PRC1 Targets during Neuronal Fate Restriction in the Developing Mouse Neocortex. Developmental Cell. 2018. 47. 6. 758-772.e5
  • Okazaki T, Gotoh Y. An Unexpected Calm: Mfge8 Controls Stem Cell Quiescence and Maintenance. Cell Stem Cell. 2018. 23. 3. 311-312
  • Lanjakornsiripan D, Pior BJ, Kawaguchi D, Furutachi S, Tahara T, Katsuyama Y, Suzuki Y, Fukazawa Y, Gotoh Y. Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers. Nature Communications. 2018. 9. 1. 1623
  • Kishi Y, Gotoh Y. Regulation of Chromatin Structure During Neural Development. Frontiers in Neuroscience. 2018. 12. 874
MISC (1):
  • Tomohiko Okazaki. ASK family in infection and inflammatory disease. Advances in Biological Regulation. 2017. 66. 37-45
Lectures and oral presentations  (321):
  • 成体マウスにおけるニューロン新生の制御
    (第85回日本内分泌学会学術総会Endocrine Forum on Women's Health 2012)
  • Gene Regulation by Polycomb Group Proteins in the Neocortical Neural Precursor Cells.
    (International Symposium on genetic and epigenetic control of cell fate 2012)
  • The role of heterochromatin protein in neurite arborization during neocortical development.
    (遺伝研研究会 (Circuit construction in the mammalian cerebral cortex: genetic and imaging approaches) 2012)
  • Chromatin regulation during neuronal differentiation
    (NIG symposium, Circuit construction in the mammalian cerebral cortex: Genetic and imaging approaches 2012)
  • The specific subcellular localization of IPS-1 is important for its function to induce apoptosis in response to viral infection
    (第85回日本生化学会大会 2012)
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