Research theme for competitive and other funds (13)：
2022 - 2025 Clarifying beneficial effects of statins to improve survival of patients with cholangiocarcinoma using the analysis of bile metabolome
2020 - 2024 Development of AI technology to detect prion activity of pathogenic proteins in nasal mucosa and its application to diagnosis of dementia
2020 - 2024 Creating a fall prevention program that the elderly can evaluate their walk-style by developing our three-dimensional acceleration sensor
2019 - 2024 A Cross-Sectional Study on Disease and Regional Diversity of Cognitive Impairment in Elderly Using Speech Analysis and Cerebral Blood Flow Activation
2020 - 2023 International cooperative study for spatial-temporal disease clustering and risk factors on emerging infectious diseases
2019 - 2022 ラクトフェリンによる炎症性腸疾患の発症予防と寛解維持および発がん予防効果
2018 - 2021 Study of two-step amyloid-beta accumulation in human brains
2017 - 2021 Simultaneous analysis of Aß oligomers, Aß fibrils and phosphrylated tau protein using fluroine-MRI
2017 - 2021 Development of online system about Advanced Directive of Living Will and its efficacy assessment
2016 - 2021 コホート・生体試料支援プラットフォーム
2017 - 2020 The research of pathological condition for clinical diagnosis of tangle only dementia
2016 - 2019 A study to elucidate mechanism, by which periodontists inducing memory impairment and to determine effect of its intervention on progression of dementia.
2018 - 2019 Verification of the sensor built-in ankle weight (Power Walk) and the effect on prevention of frailty and behavior change
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Papers (175)：
Masataka Kikuchi, Akinori Miyashita, Norikazu Hara, Kensaku Kasuga, Yuko Saito, Shigeo Murayama, Akiyoshi Kakita, Hiroyasu Akatsu, Kouichi Ozaki, Shumpei Niida, et al. Polygenic effects on the risk of Alzheimer’s disease in the Japanese population. Alzheimer's Research & Therapy. 2024. 16. 1
Mizuki Hino, Yasuto Kunii, Risa Shishido, Atsuko Nagaoka, Junya Matsumoto, Hiroyasu Akatsu, Yoshio Hashizume, Hideki Hayashi, Akiyoshi Kakita, Hiroaki Tomita, et al. Marked alteration of phosphoinositide signaling-associated molecules in postmortem prefrontal cortex with bipolar disorder. Neuropsychopharmacology Reports. 2024
Wataru Arihisa, Takeshi Kondo, Katsushi Yamaguchi, Junya Matsumoto, Hiroki Nakanishi, Yasuto Kunii, Hiroyasu Akatsu, Mizuki Hino, Yoshio Hashizume, Shumpei Sato, et al. Lipid-correlated alterations in the transcriptome are enriched in several specific pathways in the postmortem prefrontal cortex of Japanese patients with schizophrenia. Neuropsychopharmacology reports. 2023. 43. 3. 403-413
Shun Kunugi, Hiroyasu Akatsu, Kohei Watanabe. Effect of ankle weight loading and walking speed on metabolic and neuromuscular responses and lower limb kinematics during treadmill walking. Sport Sciences for Health. 2023
日本病院総合診療医学会
, THE JANPANESE SOCIETY OF INTERNAL MEDICINE
, 日本老年学会
, JAPAN SOCIETY FOR DEMENTIA RESEARCH
, 日本静脈経腸栄養学会
, THE JAPANESE SOCIETY OF NEUROPATHOLOGY
