Miwa Hideki

Affiliation and department：
Job title： Section chief
Homepage URL (1)： https://nrid.nii.ac.jp/nrid/1000080468488/

Research field (4)： Clinical pharmacy , Physiology , Neuroscience - general , Neuroscience - general

Research keywords (27)： Parvalbumin , hallucination/delusion , attention , RDoC , schizophrenia , sleep , spindle , TRN , GAD67 , GAD65 , GABA作動性ニューロン , 情動 , 行動学 , 電気生理学 , 学習 , 記憶 , マウス , グルタミン酸受容体 , fear extinction , fear conditioning , LTP , 海馬 , GABA , NMDA受容体 , シナプス可塑性 , シナプス , 扁桃体

Research theme for competitive and other funds (5)：

2019 - 2022 Neural basis of "Hallucination and delusion" using schizophrenia mouse models
2019 - 2021 Neural mechanisms underlying attention deficits in schizophrenia
2017 - 2019 「スピンドル波発生とその生理的意義」
2015 - 2016 「レトロウィルスを用いた成体海馬新生ニューロンの機能解析」
2014 - 2015 「極微細内視鏡による深部脳部位の細胞活動イメージング」

Papers (18)：

上條諭志, 山田光彦, 三輪秀樹. マウス発達期小脳プルキンエ細胞の活動抑制による自閉症スペクトラム障害様表現型の探索. 国立精神・神経医療研究センター精神保健研究所年報. 2023. 36. 213-213
Sayaka Hirai, Hideki Miwa, Hiroko Shimbo, Keisuke Nakajima, Masahiro Kondo, Tomoko Tanaka, Chiaki Ohtaka-Maruyama, Shinobu Hirai, Haruo Okado. Normal cortical laminar formation in RP58+/- mice. Molecular Psychiatry. 2023. 28. 6. 2173-2173
Sayaka Hirai, Hideki Miwa, Hiroko Shimbo, Keisuke Nakajima, Masahiro Kondo, Tomoko Tanaka, Chiaki Ohtaka-Maruyama, Shinobu Hirai, Haruo Okado. The mouse model of intellectual disability by ZBTB18/RP58 haploinsufficiency shows cognitive dysfunction with synaptic impairment. Molecular psychiatry. 2023
Tomoyuki Fujiyama, Henri Takenaka, Fuyuki Asano, Kazuya Miyanishi, Noriko Hotta-Hirashima, Yukiko Ishikawa, Satomi Kanno, Patricia Seoane-Collazo, Hideki Miwa, Mikio Hoshino, et al. Mice Lacking Cerebellar Cortex and Related Structures Show a Decrease in Slow-Wave Activity With Normal Non-REM Sleep Amount and Sleep Homeostasis. Frontiers in Behavioral Neuroscience. 2022. 16
Yukiko U. Inoue, Hideki Miwa, Kei Hori, Ryosuke Kaneko, Yuki Morimoto, Eriko Koike, Junko Asami, Satoshi Kamijo, Mitsuhiko Yamada, Mikio Hoshino, et al. Targeting Neurons with Functional Oxytocin Receptors: A Novel Set of Simple Knock-In Mouse Lines for Oxytocin Receptor Visualization and Manipulation. eneuro. 2022. 9. 1. ENEURO.0423-21.2022

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MISC (13)：

三輪秀樹, 山田光彦. GABA仮説に基づく統合失調症モデルマウスにおける海馬歯状回顆粒細胞の未成熟化について. 国立精神・神経医療研究センター精神保健研究所研究報告会プログラム・抄録集(Web). 2021. 32nd
Hideki Miwa, Radhika Basheer, James T. McKenna, James M. McNally, Robert W. McCarley, Ritchie E Brown. Roles of GAD67 in the thalamic reticular nucleus for regulating sleep spindle generation. Sleep. 2017. 40 (Suppl.1). A48-A49
Tomomi Fujieda, Tomoaki Shirao, Hideki Miwa, Yuko Sekino. New pathway of feed-forward inhibition to the lateral amygdala uncovered by optical imaging. JOURNAL OF PHYSIOLOGICAL SCIENCES. 2013. 63. S128-S128
Kojiro Hara, Tomomi Fujieda, Tomohiko Irie, Hideki Miwa, Jun-ichiro Oka, Tomoaki Shirao, Ruri Kikura-Hanajiri, Yukihiro Goda, Yuko Sekino. Effects of cannabinoid CB1 receptor activation on the neuronal responses in the mouse amygdala analyzed by voltage-sensitive dye imaging. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2013. 121. 174P-174P
Tomomi Fujieda, Tomoaki Shirao, Hideki Miwa, Yuko Sekino. Modulation of neuronal circuits by GABA(B) receptor activity in the mouse lateral amygdala. NEUROSCIENCE RESEARCH. 2011. 71. E212-E212

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Education (3)：

2003 - 2007 The University of Tokyo Graduate School of Medicine Neuroscience
2001 - 2003 東京大学大学院医学系研究科医科学専攻修士課程
1997 - 2001 Tokyo Institute of Technology School of Bioscience and Biotechnology

Professional career (1)：

Ph.D.

Work history (6)：

2018/04 - 現在 National Institute of Mental Health, National center of Neurology and Psychiatry Molecular Neuropharmacology section, Department of Neuropsychopharmacology Section chief
2019/10 - 2020/03 Massachusetts Institute of Technology Department of Brain and Cognitive Sciences Short Scholar
2015/09 - 2018/03 Harvard medical school/VA Boston Healthcare System Laboratory of Neuroscience, Department of Psychiatry Visiting assistant professor
2008/06 - 2016/07 群馬大学大学院医学系研究科遺伝発達行動学助教
2007/05 - 2008/05 慶應義塾大学医学部薬理学教室博士研究員

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Awards (4)：

2017/01 - 株式会社リバネス第33回リバネス研究費L-RAD賞
2016 - 公益財団法人中谷医工計測技術振興財団平成27年度技術交流助成
2016 - 公益財団法人中山人間科学振興財団平成27年度「社会脳のヒューマンサイエンス」国際交流助成
2015/04 - 公益財団法人上原記念生命科学財団平成26年度海外留学助成リサーチフェローシップ

Association Membership(s) (3)：

Society for Neuroscience , Physiological Society of Japan , THE JAPAN NEUROSCIENCE SOCIETY

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