2020 - 2023 Measuring molecular properties of membrane proteins using a synthetic cell micro-environment conposed of a model cell membrane and a nanometric space
2020 - 2022 Microdomain dynamics in the inner leaflet of plasma membranes as revealed by super-resolution microscopy and single-molecule imaging
2015 - 2018 Integrative understanding of linkage between molecular structures and functions of glycosphingolipids in signal regulation
2015 - 2018 Study for elucidation of the structures and functions of nano-sized membrane domains using glycolipid probes
2017 - 2018 ガングリオシドによる受容体活性制御機構の解明
2016 - 2018 アミロイドベータ毒性発現機構の高精度1分子観察による研究
2016 - 2018 リポクオリティとラフト構造・機能の相関の高精度1分子観察による解明
2015 - 2018 高精度1分子観察による基本ユニットラフト仮説の検証
2016 - 2017 脂質ラフトを介したシグナル伝達機構の1分子観察による解明
2015 - 2017 細胞膜上のディジタル式シグナル変換システムの解明
2014 - 2017 パターン化人工膜を用いた膜タンパク質のラフト親和性と機能の解析
2011 - 2016 Molecular mechanisms for maintenance of the integrity of nervous tissues by glycosphingolipids
2011 - 2015 Study on the molecular basis underlyng neurite outgrowth promotion by gangliosides
2012 - 2015 高精度1分子観察によるラフトシグナル機構の解明
2011 - 2015 統合的神経機能の制御を標的とした糖鎖の作動原理解明
2011 - 2013 Spatio-temporal analysis of cell membrane molecules involved in the enhancement of malignant properties by glycosphingolipids
2008 - 2012 1分子追跡によるラフト量子化信号システムの解明
2008 - 2011 1分子観察・操作による細胞膜ラフト上の情報伝達機構の解明
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Papers (113):
Haruka Kemmoku, Kanoko Takahashi, Kojiro Mukai, Toshiki Mori, Koichiro M. Hirosawa, Fumika Kiku, Yasunori Uchida, Yoshihiko Kuchitsu, Yu Nishioka, Masaaki Sawa, et al. Single-molecule localization microscopy reveals STING clustering at the trans-Golgi network through palmitoylation-dependent accumulation of cholesterol. Nature Communications. 2024. 15. 220
Takahiro K Fujiwara, Shinji Takeuchi, Ziya Kalay, Yosuke Nagai, Taka A Tsunoyama, Thomas Kalkbrenner, Kokoro Iwasawa, Ken P Ritchie, Kenichi G N Suzuki, Akihiro Kusumi. Development of ultrafast camera-based single fluorescent-molecule imaging for cell biology. The Journal of cell biology. 2023. 222. 8
Takahiro K Fujiwara, Taka A Tsunoyama, Shinji Takeuchi, Ziya Kalay, Yosuke Nagai, Thomas Kalkbrenner, Yuri L Nemoto, Limin H Chen, Akihiro C E Shibata, Kokoro Iwasawa, et al. Ultrafast single-molecule imaging reveals focal adhesion nano-architecture and molecular dynamics. The Journal of cell biology. 2023. 222. 8
Ayaka Isogami, Sayuri L. Higashi, Bioru Okumura, Aya Shibata, Koichiro M. Hirosawa, Kenichi G. N. Suzuki, Shinya Tsukiji, Kazunori Matsuura, Masato Ikeda. Hierarchical supramolecular structure comprising reduction-responsive DNA microspheres and semi-artificial glycopeptide-based micro-asters. Polymer Journal. 2023
Kenichi G. N. Suzuki, Naoko Komura, Hiromune Ando. Recently developed glycosphingolipid probes and their dynamic behavior in cell plasma membranes as revealed by single-molecule imaging. Glycoconjugate Journal. 2023
花島慎弥, 花島慎弥, 安田智一, 樺山一哉, 廣澤幸一朗, 鈴木健一. Modification of membrane properties of small extracellular vesicle exosomes using lipid exchange. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
Kenichi G, N. Suzuki, Koichiro M. Hirosawa, Tatsuki Isogai. Dynamics of extracellular vesicles as revealed by single-molecule imaging and super-resolution microscopy. 2021. 39. 20. 156-162
Kenichi Suzuki. Unraveling of raft organization and function by single-molecule imaging. The Lipid. 2020. 31. 1. 4-9
Protein-lipid interactions: from membrane domains to cellular networks
Wiley 2005
Lectures and oral presentations (96):
Unraveling of regulation mechanisms of Ras signaling by single-molecule imaging and super-resolution microscopy
(The 82nd Annual Meeting of the Japanese Cancer Association 2023)
Digging into caveolae by lipid and protein interactions
(The 75th annual meeting of the Japan Society for Cell Biology 2023)
Visualization analysis of signal transduction in inner leaflet of cell plasma membranes by single-moelcule imaging and super-resolution microscopy
(2023)
Regulation mechanisms of receptor activity by gangliosides as revealed by single-molecule imaging
(Canadian glycomics Symposium 2023 2023)
1993 - 1996 Kyoto University Graduate School of Engineering Department of Synthetic Chemistry and Biological Chemistry
1991 - 1993 Kyoto University Graduate School of Engineering Department of Polymer Chemistry
1987 - 1991 Kyoto University Faculty of Engineering
Professional career (1):
博士(工学) (京都大学)
Work history (10):
2023/04 - 現在 National Cancer Center Research Institute
2021/01 - 現在 Gifu University
2017/04 - 現在 Gifu University
2011/04 - 2017/03 The National Centre for Biological Sciences (NCBS)/Institute for Stem Cell Biology and Regenerative Medicine (inStem) Visiting Associate Professor
2011/04 - 2017/03 Kyoto University Institute for Integrated Cell-Material Sciences Associate Professor
2008/10 - 2012/03 JST-PRESTO
2010/04 - 2011/03 Kyoto University Institute for Frontier Medical Sciences Research Senior Lecturer
2005/04 - 2010/03 Kyoto University Institute for Frontier Medical Sciences Research Assistant Professor
1999/02 - 2005/03 科学技術振興機構ERATO楠見膜組織能プロジェクト 研究員
1996/11 - 1999/01 Duke University Medical Center
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Committee career (3):
2023/06 - 2027/06 The japanese Conference on the Biochemistry of Lipids Secretary