Rchr
J-GLOBAL ID：201101049311559600   Update date: Apr. 09, 2026

Hirabayashi Yusuke

Hirabayashi Yusuke
Affiliation and department：
The University of Tokyo The Graduate School of Engineering

About The University of Tokyo The Graduate School of Engineering


Homepage URL  (2)： http://www.chembio.t.u-tokyo.ac.jp/department/lab/hirabayashi.html ,  http://www.chembio.t.u-tokyo.ac.jp/e/department/lab/hirabayashi.html
Research field  (3)： Neuroscience - general ,  Cell biology ,  Developmental biology
Research keywords  (4)： 包括脳ネットワーク ,  統合脳・分子脳科学 ,  脳・神経 ,  発生分化
Research theme for competitive and other funds  (22)：
  • 2024 - 2027 超解像度高速一分子イメージングによるオルガネラ繋留因子の動態解析
  • 2024 - 2026 タンパク質天然変性領域によるミトコンドリアの細胞内局在制御機構の解明
  • 2024 - 2026 ミトコンドリアー小胞体接触の形態と大きさの制御機構の解明
  • 2024 - 2025 ミトコンドリアを介したアミノ酸生合成がシナプスの多様性に果たす役割
  • 2022 - 2025 ミトコンドリアを介したアミノ酸生合成がシナプスの多様性に果たす役割
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Papers (49)：
  • Isshin Shiiba, Yuto Ishikawa, Hijiri Oshio, Naoki Ito, Fuya Yamaguchi, Shun Nagashima, Hideya Ando, Keitaro Umezawa, Yuri Miura, Yuhei Araiso, et al. STIM1-Mitofusin2 interactions tether mitochondria and melanosome contacts that promote melanosome maturation. Nature Communications. 2026
  • Christian Hoffmann, Takahiro Nagao, Taka A Tsunoyama, Johannes Vincent Tromm, Chinyere Logan, Koki Nakamura, Han Wang, Frans Bianchi, Geert van den Bogaar, Akihiro Kusumi, et al. Membrane-protein-mediated phase separation orchestrates organelle contact sites. Molecular cell. 2026. 86. 1. 135-149
  • Nakamura Koki, Hirabayashi Yusuke. Mechanism and function of mitochondria-endoplasmic reticulum contact site formation by the PDZD8-FKBP8 complex in mammalian cells. 2025. 97. 2. 236-240
  • Koki Nakamura, Saeko Aoyama-Ishiwatari, Takahiro Nagao, Mohammadreza Paaran, Christopher J Obara, Yui Sakurai-Saito, Jake Johnston, Yudan Du, Shogo Suga, Masafumi Tsuboi, et al. Mitochondrial complexity is regulated at ER-mitochondria contact sites via PDZD8-FKBP8 tethering. Nature communications. 2025. 16. 1. 3401-3401
  • Masahiro Wakano, Masaya Tsunoda, Keiji Murayama, Jumpei Morimoto, Ryosuke Ueki, Saeko Aoyama-Ishiwatari, Yusuke Hirabayashi, Hiroyuki Asanuma, Shinsuke Sando. Reversible Optical Control of Receptor Tyrosine Kinase Activity and ERK Dynamics Using Azobenzene-Carrying DNA Aptamer Agonist. Journal of the American Chemical Society. 2025. 147. 13. 11477-11484
ｍore...
MISC (5)：
Books (1)：
  • BRAIN SCIENCE REVIEW 2022
    2022 ISBN:9784910513065
Lectures and oral presentations  (68)：
  • Properties and functions of axonal mitochondria in cortical pyramidal neurons
    (APPW2025 2025)
  • 大脳皮質ニューロンにおけるミトコンドリアを介した神経伝達物質産生制御
    (量子医学研究所セミナー 2025)
  • Direct conversion of glucose into neurotransmitter glutamate via neuronal mitochondria
    (AMED脳統合・精神疾患関連モデル・トランスレーショナル研究会議 2025)
  • Across the membranes: to yield potential of limited carbon source in neurons
    (DZNE-Berlin Seminar 2025)
  • Direct conversion of glucose into neurotransmitter glutamate via neuronal mitochondria
    (Symposium on Life Science Technologies 2025)
ｍore...
Professional career (1)：
  • PhD
Work history (9)：
  • 2018/10 - 現在 The University of Tokyo Department of Chemistry and Biotechnology, School of Engineering Associate Professor
  • 2016/10 - 2018/09 Columbia University Department of Neuroscience JST PRESTO Researcher
  • 2015/03 - 2016/09 Columbia University Department of Neuroscience Research Associate
  • 2013/11 - 2015/02 Columbia University Department of Neuroscience JSPS fellow
  • 2013/03 - 2013/10 The Scripps Research Institute Department of Cell Biology JSPS fellow
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